Search Results - "Rice, Kacie"

Natural Variants of the KPC-2 Carbapenemase have Evolved Increased Catalytic Efficiency for Ceftazidime Hydrolysis at the Cost of Enzyme Stability by Mehta, Shrenik C, Rice, Kacie, Palzkill, Timothy

“…The spread of β-lactamases that hydrolyze penicillins, cephalosporins and carbapenems among Gram-negative bacteria has limited options for treating bacterial…”
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Natural Variants of the KPC-2 Carbapenemase have Evolved Increased Catalytic Efficiency for Ceftazidime Hydrolysis at the Cost of Enzyme Stability: e1004949 by Mehta, Shrenik C, Rice, Kacie, Palzkill, Timothy

“…The spread of β-lactamases that hydrolyze penicillins, cephalosporins and carbapenems among Gram-negative bacteria has limited options for treating bacterial…”
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Deep Sequencing of Systematic Combinatorial Libraries Reveals β-Lactamase Sequence Constraints at High Resolution by Deng, Zhifeng, Huang, Wanzhi, Bakkalbasi, Erol, Brown, Nicholas G., Adamski, Carolyn J., Rice, Kacie, Muzny, Donna, Gibbs, Richard A., Palzkill, Timothy

“…In this study, combinatorial libraries were used in conjunction with ultrahigh-throughput sequencing to comprehensively determine the impact of each of the 19…”
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Role of β‐lactamase residues in a common interface for binding the structurally unrelated inhibitory proteins BLIP and BLIP‐II by Fryszczyn, Bartlomiej G., Adamski, Carolyn J., Brown, Nicholas G., Rice, Kacie, Huang, Wanzhi, Palzkill, Timothy

“…The β‐lactamase inhibitory proteins (BLIPs) are a model system for examining molecular recognition in protein‐protein interactions. BLIP and BLIP‐II are…”
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Role of [beta]-lactamase residues in a common interface for binding the structurally unrelated inhibitory proteins BLIP and BLIP-II by Fryszczyn, Bartlomiej G, Adamski, Carolyn J, Brown, Nicholas G, Rice, Kacie, Huang, Wanzhi, Palzkill, Timothy

“…The [beta]-lactamase inhibitory proteins (BLIPs) are a model system for examining molecular recognition in protein-protein interactions. BLIP and BLIP-II are…”
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Engineering Specificity from Broad to Narrow: Design of a β‑Lactamase Inhibitory Protein (BLIP) Variant That Exclusively Binds and Detects KPC β‑Lactamase by Chow, Dar-Chone, Rice, Kacie, Huang, Wanzhi, Atmar, Robert L, Palzkill, Timothy

“…The β-lactamase inhibitory protein (BLIP) binds and inhibits a wide range of class A β-lactamases including the TEM-1 β-lactamase (K i = 0.5 nM), which is…”
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Engineering specificity from broad to narrow: Design of a BLIP variant that exclusively binds and detects KPC β-lactamase by Chow, Dar-Chone, Rice, Kacie, Huang, Wanzhi, Atmar, Robert L., Palzkill, Timothy

“…The β-lactamase inhibitory protein (BLIP) binds and inhibits a wide range of class A β-lactamases including the TEM-1 β-lactamase ( K i = 0.5 nM), which is…”
Get full text