Search Results - "Rice, KC"

Opioid receptor-mediated hyperalgesia and antinociceptive tolerance induced by sustained opiate delivery by Gardell, Luis R., King, Tamara, Ossipov, Michael H., Rice, Kenner C., Lai, Josephine, Vanderah, Todd W., Porreca, Frank

“…Opiates are commonly used to treat moderate to severe pain and can be used over prolonged periods in states of chronic pain such as those associated with…”
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Gonadal hormone modulation of mu, kappa, and delta opioid antinociception in male and female rats by Stoffel, Erin C, Ulibarri, Catherine M, Folk, John E, Rice, Kenner C, Craft, Rebecca M

“…Previous studies suggest that sex differences in morphine antinociception in rodents might be attributed to the activational effects of gonadal hormones. The…”
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Activation of G-proteins by morphine and codeine congeners: insights to the relevance of O- and N-demethylated metabolites at mu- and delta-opioid receptors by Thompson, Chad M, Wojno, Heidi, Greiner, Elisabeth, May, Everette L, Rice, Kenner C, Selley, Dana E

“…Phenotypic differences in analgesic sensitivity to codeine (3-methoxymorphine) results from polymorphisms in cytochrome P450-2D6, which catalyzes…”
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SNC 80, a selective, nonpeptidic and systemically active opioid delta agonist by Bilsky, E J, Calderon, S N, Wang, T, Bernstein, R N, Davis, P, Hruby, V J, McNutt, R W, Rothman, R B, Rice, K C, Porreca, F

“…The present study has investigated the pharmacology of SNC 80, a nonpeptidic ligand proposed to be a selective delta agonist in vitro and in vivo. SNC 80 was…”
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Delta opioid antagonist effects of buprenorphine in rhesus monkeys by Negus, S.S, Bidlack, J.M, Mello, N.K, Furness, M.S, Rice, K.C, Brandt, M.R

“…Buprenorphine is an opioid with high affinity for delta, mu and kappa opioid receptors. The delta receptor-mediated effects of buprenorphine in vivo have not…”
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Orphanin FQ inhibits capsaicin‐induced thermal nociception in monkeys by activation of peripheral ORL1 receptors by Ko, M C H, Naughton, N N, Traynor, J R, Song, M S, Woods, J H, Rice, K C, McKnight, A T

“…Orphanin FQ (OFQ), an endogenous peptide for ORL1 receptors, has been identified. Although the actions of OFQ have much in common with those of opioid peptides…”
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Studies into the direct oxidation of codeinone to 14-hydroxycodeinone by Coop, Andrew, Rice, Kenner C

“…The direct oxidation of codeinone ( 5) to 14-hydroxycodeinone ( 6) was investigated with a wide range of oxidizing agents. The majority of reagnets gave little…”
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DAT isn’t all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling by Northcutt, A L, Hutchinson, M R, Wang, X, Baratta, M V, Hiranita, T, Cochran, T A, Pomrenze, M B, Galer, E L, Kopajtic, T A, Li, C M, Amat, J, Larson, G, Cooper, D C, Huang, Y, O'Neill, C E, Yin, H, Zahniser, N R, Katz, J L, Rice, K C, Maier, S F, Bachtell, R K, Watkins, L R

“…The initial reinforcing properties of drugs of abuse, such as cocaine, are largely attributed to their ability to activate the mesolimbic dopamine system…”
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Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats by Grace, Peter M., Strand, Keith A., Galer, Erika L., Rice, Kenner C., Maier, Steven F., Watkins, Linda R.

“…•Morphine administration after peripheral nerve injury increases spinal DAMP levels.•Elevation of DAMPs persists through at least 5weeks after morphine…”
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A Stable Heroin Analogue That Can Serve as a Vaccine Hapten to Induce Antibodies That Block the Effects of Heroin and Its Metabolites in Rodents and That Cross-React Immunologically with Related Drugs of Abuse by Sulima, Agnieszka, Jalah, Rashmi, Antoline, Joshua F. G, Torres, Oscar B, Imler, Gregory H, Deschamps, Jeffrey R, Beck, Zoltan, Alving, Carl R, Jacobson, Arthur E, Rice, Kenner C, Matyas, Gary R

“…An improved synthesis of a haptenic heroin surrogate 1 (6-AmHap) is reported. The intermediate needed for the preparation of 1 was described in the route in…”
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Opioid activation of toll-like receptor 4 contributes to drug reinforcement by Hutchinson, M R, Northcutt, A L, Hiranita, T, Wang, X, Lewis, S S, Thomas, J, van Steeg, K, Kopajtic, T A, Loram, L C, Sfregola, C, Galer, E, Miles, N E, Bland, S T, Amat, J, Rozeske, R R, Maslanik, T, Chapman, T R, Strand, K A, Fleshner, M, Bachtell, R K, Somogyi, A A, Yin, H, Katz, J L, Rice, K C, Maier, S F, Watkins, L R

“…Opioid action was thought to exert reinforcing effects solely via the initial agonism of opioid receptors. Here, we present evidence for an additional novel…”
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Evidence that opioids may have toll-like receptor 4 and MD-2 effects by Hutchinson, Mark R, Zhang, Yingning, Shridhar, Mitesh, Evans, John H, Buchanan, Madison M, Zhao, Tina X, Slivka, Peter F, Coats, Benjamen D, Rezvani, Niloofar, Wieseler, Julie, Hughes, Travis S, Landgraf, Kyle E, Chan, Stefanie, Fong, Stephanie, Phipps, Simon, Falke, Joseph J, Leinwand, Leslie A, Maier, Steven F, Yin, Hang, Rice, Kenner C, Watkins, Linda R

“…Abstract Opioid-induced proinflammatory glial activation modulates wide-ranging aspects of opioid pharmacology including: opposition of acute and chronic…”
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Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study by Herkenham, M, Lynn, AB, Johnson, MR, Melvin, LS, de Costa, BR, Rice, KC

“…A potent, synthetic cannabinoid was radiolabeled and used to characterize and precisely localize cannabinoid receptors in slide-mounted sections of rat brain…”
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Exercise Reverses Nociceptive Sensitization, Upregulated Neuropeptide Signaling, Inflammatory Changes, Anxiety, and Memory Impairment in a Mouse Tibia Fracture Model by Shi, Xiaoyou, Guo, Tian-zhi, Li, Wenwu, Sahbaie, Peyman, Rice, Kenner C, Sulima, Agnieszka, Clark, J David, Kingery, Wade S

“…WHAT WE ALREADY KNOW ABOUT THIS TOPIC WHAT THIS ARTICLE TELLS US THAT IS NEW BACKGROUND:This study tested the hypothesis that ad lib running wheel exercise in…”
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Effects of acute treatments with the serotonin 2A antagonist M100907 alone or in combination with the serotonin 2C agonist WAY163909 on methamphetamine self-administration in rhesus monkeys by Odabas-Geldiay, Melis, Shields, Hannah, Berro, Lais F., Rice, Kenner C., Howell, Leonard L.

“…•Methamphetamine (METH) maintained self-administration (SA) in rhesus monkeys.•The 5-HT2A receptor (R) antagonist M100907 dose-dependently attenuated METH…”
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Targeting the Toll of Drug Abuse: The Translational Potential of Toll-Like Receptor 4 by Bachtell, Ryan, Hutchinson, Mark R, Wang, Xiaohui, Rice, Kenner C, Maier, Steven F, Watkins, Linda R

“…There is growing recognition that glial proinflammatory activation importantly contributes to the rewarding and reinforcing effects of a variety of drugs of…”
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Wistar rats acquire and maintain self-administration of 20 % ethanol without water deprivation, saccharin/sucrose fading, or extended access training by Augier, E., Flanigan, M., Dulman, R. S., Pincus, A., Schank, J. R., Rice, K.C., Kejun, C., Heilig, M., Tapocik, J. D.

“…Rationale Operant self-administration (SA) is an important model of motivation to consume ethanol (EtOH), but low rates of voluntary consumption in rats are…”
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Salvinorin A: A Potent Naturally Occurring Nonnitrogenous κ Opioid Selective Agonist by Roth, Bryan L., Baner, Karen, Westkaemper, Richard, Siebert, Daniel, Rice, Kenner C., Steinberg, SeAnna, Ernsberger, Paul, Rothman, Richard B.

“…Salvia divinorum, whose main active ingredient is the neoclerodane diterpene Salvinorin A, is a hallucinogenic plant in the mint family that has been used in…”
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Role of mu-opioid agonist efficacy on antinociceptive interactions between mu agonists and the nociceptin opioid peptide agonist Ro 64-6198 in rhesus monkeys by Cornelissen, Jeremy C., Steele, Floyd F., Tenney, Rebekah D., Obeng, Samuel, Rice, Kenner C., Zhang, Yan, Banks, Matthew L.

“…Mu-opioid receptor agonists are clinically effective analgesics, but also produce undesirable effects that limit their clinical utility. The nociceptin opioid…”
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Effects of kappa opioids in an assay of pain-depressed intracranial self-stimulation in rats by Negus, S. Stevens, Morrissey, Ember M., Rosenberg, Marisa, Cheng, K., Rice, Kenner C.

“…Rationale Selective, centrally acting kappa opioid agonists produce antinociception in a wide range of preclinical assays, but these compounds perform poorly…”
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