Search Results - "Rice, Frank L"

TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons by Kwan, Kelvin Y, Glazer, Joshua M, Corey, David P, Rice, Frank L, Stucky, Cheryl L

“…Transient receptor potential ankyrin 1 (TRPA1) is expressed by nociceptive neurons of the dorsal root ganglia (DRGs) and trigeminal ganglia, but its roles in…”
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Loss of Inhibitory Interneurons in the Dorsal Spinal Cord and Elevated Itch in Bhlhb5 Mutant Mice by Ross, Sarah E., Mardinly, Alan R., McCord, Alejandra E., Zurawski, Jonathan, Cohen, Sonia, Jung, Cynthia, Hu, Linda, Mok, Stephanie I., Shah, Anar, Savner, Erin M., Tolias, Christos, Corfas, Roman, Chen, Suzhen, Inquimbert, Perrine, Xu, Yi, McInnes, Roderick R., Rice, Frank L., Corfas, Gabriel, Ma, Qiufu, Woolf, Clifford J., Greenberg, Michael E.

“…Itch is the least well understood of all the somatic senses, and the neural circuits that underlie this sensation are poorly defined. Here we show that the…”
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Topographically Distinct Epidermal Nociceptive Circuits Revealed by Axonal Tracers Targeted to Mrgprd by Zylka, Mark J., Rice, Frank L., Anderson, David J.

“…The brain receives sensory input from diverse peripheral tissues, including the skin, the body's largest sensory organ. Using genetically encoded axonal…”
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H3 receptors and pain modulation: peripheral, spinal, and brain interactions by Hough, Lindsay B, Rice, Frank L

“…Histamine H(3) receptors (H(3)Rs), distributed within the brain, the spinal cord, and on specific types of primary sensory neurons, can modulate pain…”
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Air-stimulated ATP release from keratinocytes occurs through connexin hemichannels by Barr, Travis P, Albrecht, Phillip J, Hou, Quanzhi, Mongin, Alexander A, Strichartz, Gary R, Rice, Frank L

“…Cutaneous ATP release plays an important role in both epidermal stratification and chronic pain, but little is known about ATP release mechanisms in…”
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Anatomy and immunochemical characterization of the non-arterial peptidergic diffuse dural innervation of the rat and Rhesus monkey: Implications for functional regulation and treatment in migraine by Rice, Frank L, Xie, Jennifer Y, Albrecht, Phillip J, Acker, Emily, Bourgeois, Justin, Navratilova, Edita, Dodick, David W, Porreca, Frank

“…Objective The interplay between neuronal innervation and other cell types underlies the physiological functions of the dura mater and contributes to…”
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CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids by Ibrahim, Mohab M, Porreca, Frank, Lai, Josephine, Albrecht, Phillip J, Rice, Frank L, Khodorova, Alla, Davar, Gudarz, Makriyannis, Alexandros, Vanderah, Todd W, Mata, Heriberto P, Malan, Jr, T Philip

“…CB 2 cannabinoid receptor-selective agonists are promising candidates for the treatment of pain. CB 2 receptor activation inhibits acute, inflammatory, and…”
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The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin by Rice, Frank L, Houk, George, Wymer, James P, Gosline, Sara J C, Guinney, Justin, Wu, Jianqiang, Ratner, Nancy, Jankowski, Michael P, La Rosa, Salvo, Dockum, Marilyn, Storey, James R, Carroll, Steven L, Albrecht, Phillip J, Riccardi, Vincent M

“…In addition to large plexiform neurofibromas (pNF), NF1 patients are frequently disfigured by cutaneous neurofibromas (cNF) and are often afflicted with…”
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Cutaneous targets for topical pain medications in patients with neuropathic pain: individual differential expression of biomarkers supports the need for personalized medicine by Albrecht, Phillip J, Liu, Yi, Houk, George, Ruggiero, Beth, Banov, Daniel, Dockum, Marilyn, Day, A J, Rice, Frank L, Bassani, Gus

“…Numerous potential cutaneous targets exist for treating chronic pain with topically applied active pharmaceutical ingredients. This preliminary human skin…”
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ASIC3, an Acid-Sensing Ion Channel, is Expressed in Metaboreceptive Sensory Neurons by Molliver, Derek C, Immke, David C, Fierro, Leonardo, Paré, Michel, Rice, Frank L, McCleskey, Edwin W

“…Background: ASIC3, the most sensitive of the acid-sensing ion channels, depolarizes certain rat sensory neurons when lactic acid appears in the extracellular…”
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Keratinocyte Biomarkers Distinguish Painful Diabetic Peripheral Neuropathy Patients and Correlate With Topical Lidocaine Responsiveness by Albrecht, Phillip J, Houk, George, Ruggiero, Elizabeth, Dockum, Marilyn, Czerwinski, Margaret, Betts, Joseph, Wymer, James P, Argoff, Charles E, Rice, Frank L

“…This study investigated quantifiable measures of cutaneous innervation and algesic keratinocyte biomarkers to determine correlations with clinical measures of…”
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Similarities and differences in the innervation of mystacial vibrissal follicle-sinus complexes in the rat and cat: A confocal microscopic study by Ebara, Satomi, Kumamoto, Kenzo, Matsuura, Tadao, Mazurkiewicz, Joseph E., Rice, Frank L.

“…Our confocal three‐dimensional analyses revealed substantial differences in the innervation to vibrissal follicle‐sinus complexes (FSCs) in the rat and cat…”
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Immunohistochemical localization of histamine H3 receptors in rodent skin, dorsal root ganglia, superior cervical ganglia, and spinal cord : Potential antinociceptive targets by CANNON, Keri E, CHAZOT, Paul L, HANN, Victoria, SHENTON, Fiona, HOUGH, Lindsay B, RICE, Frank L

“…Activation of histamine H3 receptors (H3Rs) reduces inflammation and nociception, but the existence of H3Rs on peripheral innervation has never been…”
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Endothelin-B receptor activation triggers an endogenous analgesic cascade at sites of peripheral injury by Davar, Gudarz, Khodorova, Alla, Navarro, Betsy, Jouaville, Laurence Sophie, Murphy, Jo-Ellen, Rice, Frank L, Mazurkiewicz, Joseph E, Long-Woodward, Denise, Stoffel, Markus, Strichartz, Gary R, Yukhananov, Rus

“…Endothelin-1 (ET-1) is a newly described pain mediator that is involved in the pathogenesis of pain states ranging from trauma to cancer. ET-1 is synthesized…”
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Dependence on the transcription factor Shox2 for specification of sensory neurons conveying discriminative touch by Abdo, Hind, Li, Lili, Lallemend, Francois, Bachy, Isabelle, Xu, Xiao-Jun, Rice, Frank L., Ernfors, Patrik

“…Touch sensation is mediated by specific subtypes of sensory neurons which develop in a hierarchical process from common early progenitor neurons, but the…”
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Differential hypertrophy and atrophy among all types of cutaneous innervation in the glabrous skin of the monkey hand during aging and naturally occurring type 2 diabetes by Paré, Michel, Albrecht, Phillip J., Noto, Christopher J., Bodkin, Noni L., Pittenger, Gary L., Schreyer, David J., Tigno, Xenia T., Hansen, Barbara C., Rice, Frank L.

“…Diabetic neuropathy (DN) is a common severe complication of type 2 diabetes. The symptoms of chronic pain, tingling, and numbness are generally attributed to…”
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Adaptations in the structure and innervation of follicle-sinus complexes to an aquatic environment as seen in the Florida manatee (Trichechus manatus latirostris) by Sarko, Diana K., Reep, Roger L., Mazurkiewicz, Joseph E., Rice, Frank L.

“…Florida manatees are large‐bodied aquatic herbivores that use large tactile vibrissae for several purposes. Facial vibrissae are used to forage in a turbid…”
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Manatee vibrissae: evidence for a "lateral line" function by Reep, Roger L., Gaspard III, Joseph C., Sarko, Diana, Rice, Frank L., Mann, David A., Bauer, Gordon B.

“…Aquatic mammals use vibrissae to detect hydrodynamic stimuli over a range from 5 to 150 Hz, similar to the range detected by lateral line systems in fishes and…”
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Human-like cutaneous neuropathologies associated with a porcine model of peripheral neuritis: A translational platform for neuropathic pain by Rice, Frank L, Castel, David, Ruggiero, Elizabeth, Dockum, Marilyn, Houk, George, Sabbag, Itai, Albrecht, Phillip J, Meilin, Sigal

“…Highlights • Pig peripheral neuritis trauma model mimics cutaneous human pathologies. • Pig skin anatomically similar to humans, unlike rodent. • Pig PNT model…”
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Distribution and terminal arborizations of cutaneous mechanoreceptors in the glabrous finger pads of the monkey by Paré, Michel, Smith, Allan M., Rice, Frank L.

“…Recent electrophysiological studies demonstrated that neurons in the somatosensory cortex of monkeys respond to tangential forces applied to glabrous skin. To…”
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