Search Results - "Rice, Edward"

A mechanical metamaterial made from a DNA hydrogel by Lee, Jong Bum, Peng, Songming, Yang, Dayong, Roh, Young Hoon, Funabashi, Hisakage, Park, Nokyoung, Rice, Edward J., Chen, Liwei, Long, Rong, Wu, Mingming, Luo, Dan

“…Metamaterials are artificial substances that are structurally engineered to have properties not typically found in nature. To date, almost all metamaterials…”
Get full text

Prediction of histone post-translational modification patterns based on nascent transcription data by Wang, Zhong, Chivu, Alexandra G., Choate, Lauren A., Rice, Edward J., Miller, Donald C., Chu, Tinyi, Chou, Shao-Pei, Kingsley, Nicole B., Petersen, Jessica L., Finno, Carrie J., Bellone, Rebecca R., Antczak, Douglas F., Lis, John T., Danko, Charles G.

“…The role of histone modifications in transcription remains incompletely understood. Here, we examine the relationship between histone modifications and…”
Get full text

New Approaches for Genome Assembly and Scaffolding by Rice, Edward S, Green, Richard E

“…Affordable, high-throughput DNA sequencing has accelerated the pace of genome assembly over the past decade. Genome assemblies from high-throughput, short-read…”
Get full text

Chromatin run-on and sequencing maps the transcriptional regulatory landscape of glioblastoma multiforme by Chu, Tinyi, Rice, Edward J., Booth, Gregory T., Salamanca, H. Hans, Wang, Zhong, Core, Leighton J., Longo, Sharon L., Corona, Robert J., Chin, Lawrence S., Lis, John T., Kwak, Hojoong, Danko, Charles G.

“…The human genome encodes a variety of poorly understood RNA species that remain challenging to identify using existing genomic tools. We developed chromatin…”
Get full text

Corporate tax cuts, merger activity, and shareholder wealth by Blouin, Jennifer L., Fich, Eliezer M., Rice, Edward M., Tran, Anh L.

“…We study the impact of the Domestic Production Activities Deduction (DPAD) on mergers and acquisitions. DPAD reduces corporate tax rates on income from work or…”
Get full text

RNA polymerase II dynamics shape enhancer–promoter interactions by Barshad, Gilad, Lewis, James J., Chivu, Alexandra G., Abuhashem, Abderhman, Krietenstein, Nils, Rice, Edward J., Ma, Yitian, Wang, Zhong, Rando, Oliver J., Hadjantonakis, Anna-Katerina, Danko, Charles G.

“…How enhancers control target gene expression over long genomic distances remains an important unsolved problem. Here we investigated enhancer–promoter…”
Get full text

Initiation of mtDNA transcription is followed by pausing, and diverges across human cell types and during evolution by Blumberg, Amit, Rice, Edward J, Kundaje, Anshul, Danko, Charles G, Mishmar, Dan

“…Mitochondrial DNA (mtDNA) genes are long known to be cotranscribed in polycistrones, yet it remains impossible to study nascent mtDNA transcripts…”
Get full text

Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment by Trujillo, Cleber A, Rice, Edward S, Schaefer, Nathan K, Chaim, Isaac A, Wheeler, Emily C, Madrigal, Assael A, Buchanan, Justin, Preissl, Sebastian, Wang, Allen, Negraes, Priscilla D, Szeto, Ryan A, Herai, Roberto H, Huseynov, Alik, Ferraz, Mariana S A, Borges, Fernando S, Kihara, Alexandre H, Byrne, Ashley, Marin, Maximillian, Vollmers, Christopher, Brooks, Angela N, Lautz, Jonathan D, Semendeferi, Katerina, Shapiro, Beth, Yeo, Gene W, Smith, Stephen E P, Green, Richard E, Muotri, Alysson R

“…The evolutionarily conserved splicing regulator neuro-oncological ventral antigen 1 ( ) plays a key role in neural development and function. also includes a…”
Get full text

A-MYB and BRDT-dependent RNA Polymerase II pause release orchestrates transcriptional regulation in mammalian meiosis by Alexander, Adriana K., Rice, Edward J., Lujic, Jelena, Simon, Leah E., Tanis, Stephanie, Barshad, Gilad, Zhu, Lina, Lama, Jyoti, Cohen, Paula E., Danko, Charles G.

“…During meiotic prophase I, spermatocytes must balance transcriptional activation with homologous recombination and chromosome synapsis, biological processes…”
Get full text

Characterizing RNA stability genome-wide through combined analysis of PRO-seq and RNA-seq data by Blumberg, Amit, Zhao, Yixin, Huang, Yi-Fei, Dukler, Noah, Rice, Edward J, Chivu, Alexandra G, Krumholz, Katie, Danko, Charles G, Siepel, Adam

“…The concentrations of distinct types of RNA in cells result from a dynamic equilibrium between RNA synthesis and decay. Despite the critical importance of RNA…”
Get full text

ER-positive breast cancer cells are poised for RET-mediated endocrine resistance by Horibata, Sachi, Rice, Edward J, Mukai, Chinatsu, Marks, Brooke A, Sams, Kelly, Zheng, Hui, Anguish, Lynne J, Coonrod, Scott A, Danko, Charles G

“…The RET tyrosine kinase signaling pathway is involved in the development of endocrine resistant ER+ breast cancer. However, we know little about how ER+ cells…”
Get full text

GDNF-RET signaling and EGR1 form a positive feedback loop that promotes tamoxifen resistance via cyclin D1 by Marks, Brooke A, Pipia, Ilissa M, Mukai, Chinatsu, Horibata, Sachi, Rice, Edward J, Danko, Charles G, Coonrod, Scott A

“…Rearranged during transfection (RET) tyrosine kinase signaling has been previously implicated in endocrine resistant breast cancer, however the mechanism by…”
Get full text

RNA Pol II pausing facilitates phased pluripotency transitions by buffering transcription by Abuhashem, Abderhman, Chivu, Alexandra G, Zhao, Yixin, Rice, Edward J, Siepel, Adam, Danko, Charles G, Hadjantonakis, Anna-Katerina

“…Promoter-proximal RNA Pol II pausing is a critical step in transcriptional control. Pol II pausing has been predominantly studied in tissue culture systems…”
Get full text

The immune cell landscape and response of Marek’s disease resistant and susceptible chickens infected with Marek’s disease virus by Warren, Wesley C., Rice, Edward S., Meyer, Ashley, Hearn, Cari J., Steep, Alec, Hunt, Henry D., Monson, Melissa S., Lamont, Susan J., Cheng, Hans H.

“…Genetically resistant or susceptible chickens to Marek’s disease (MD) have been widely used models to identify the molecular determinants of these phenotypes…”
Get full text

A chromosome-scale fishing cat reference genome for the evaluation of potential germline risk variants by Carroll, Rachel A., Rice, Edward S., Murphy, William J., Lyons, Leslie A., Thibaud-Nissen, Francoise, Coghill, Lyndon M., Swanson, William F., Terio, Karen A., Boyd, Tyler, Warren, Wesley C.

“…The fishing cat, Prionailurus viverrinus , faces a population decline, increasing the importance of maintaining healthy zoo populations. Unfortunately,…”
Get full text

Identification and prediction of developmental enhancers in sea urchin embryos by Arenas-Mena, César, Miljovska, Sofija, Rice, Edward J, Gurges, Justin, Shashikant, Tanvi, Wang, Zihe, Ercan, Sevinç, Danko, Charles G

“…The transcription of developmental regulatory genes is often controlled by multiple cis-regulatory elements. The identification and functional characterization…”
Get full text

Contractual revisions in compensation: Evidence from merger bonuses to target CEOs by Fich, Eliezer M., Rice, Edward M., Tran, Anh L.

“…Do merger bonuses to target CEOs facilitate a wealth transfer from target to acquirer shareholders? We test this hypothesis against an alternative that bonuses…”
Get full text

Multiple stages of evolutionary change in anthrax toxin receptor expression in humans by Choate, Lauren A., Barshad, Gilad, McMahon, Pierce W., Said, Iskander, Rice, Edward J., Munn, Paul R., Lewis, James J., Danko, Charles G.

“…The advent of animal husbandry and hunting increased human exposure to zoonotic pathogens. To understand how a zoonotic disease may have influenced human…”
Get full text

Natural selection shaped the rise and fall of passenger pigeon genomic diversity by Murray, Gemma G. R., Soares, André E. R., Novak, Ben J., Schaefer, Nathan K., Cahill, James A., Baker, Allan J., Demboski, John R., Doll, Andrew, Da Fonseca, Rute R., Fulton, Tara L., Gilbert, M. Thomas P., Heintzman, Peter D., Letts, Brandon, McIntosh, George, O’Connell, Brendan L., Peck, Mark, Pipes, Marie-Lorraine, Rice, Edward S., Santos, Kathryn M., Sohrweide, A. Gregory, Vohr, Samuel H., Corbett-Detig, Russell B., Green, Richard E., Shapiro, Beth

“…The extinct passenger pigeon was once the most abundant bird in North America, and possibly the world. Although theory predicts that large populations will be…”
Get full text

A bi-stable feedback loop between GDNF, EGR1, and ERα contribute to endocrine resistant breast cancer by Horibata, Sachi, Rice, Edward J, Zheng, Hui, Mukai, Chinatsu, Chu, Tinyi, Marks, Brooke A, Coonrod, Scott A, Danko, Charles G

“…Discovering regulatory interactions between genes that specify the behavioral properties of cells remains an important challenge. We used the dynamics of…”
Get full text