Search Results - "Rice, Ann C"
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Assessment of APOE in atypical parkinsonism syndromes
Published in Neurobiology of disease (01-07-2019)“…Atypical parkinsonism syndromes are a heterogeneous group of neurodegenerative disorders that include corticobasal degeneration (CBD), Lewy body dementia…”
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2
A New Animal Model of Hemolytic Hyperbilirubinemia-Induced Bilirubin Encephalopathy (Kernicterus)
Published in Pediatric research (01-09-2008)“…Neonatal hyperbilirubinemia can cause bilirubin encephalopathy (kernicterus). Spontaneously jaundiced (jj) Gunn rats treated with sulfonamide (sulfa) to…”
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3
Cyclosporin A improves brain tissue oxygen consumption and learning/memory performance after lateral fluid percussion injury in rats
Published in Journal of neurotrauma (01-07-2002)“…Traumatic brain injury (TBI) triggers a complex pathophysiological cascade, leading to cell death. A major factor in the pathogenesis of TBI is neuronal…”
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4
Lactate administration attenuates cognitive deficits following traumatic brain injury
Published in Brain research (22-02-2002)“…Moderately head injured patients often suffer long term neurological sequelae. There is no therapy for brain trauma and current treatments aim only to minimize…”
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5
NMDA receptor activation during status epilepticus is required for the development of epilepsy
Published in Brain research (26-01-1998)“…NMDA receptor activation has been implicated in modulating seizure activity; however, its complete role in the development of epilepsy is unknown. The…”
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6
Multi-neuronal recordings in the Basal Ganglia in normal and dystonic rats
Published in Frontiers in systems neuroscience (01-01-2011)“…Classical rate-based pathway models are invaluable for conceptualizing direct/indirect basal ganglia pathways, but cannot account for many aspects of normal…”
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7
Mitochondrial DNA copy numbers in pyramidal neurons are decreased and mitochondrial biogenesis transcriptome signaling is disrupted in Alzheimer's disease hippocampi
Published in Journal of Alzheimer's disease (01-01-2014)“…Alzheimer's disease (AD) is the major cause of adult-onset dementia and is characterized in its pre-diagnostic stage by reduced cerebral cortical glucose…”
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8
Initial characterization of behavior and ketamine response in a mouse knockout of the post-synaptic effector gene Anks1b
Published in Neuroscience letters (22-02-2017)“…•Human ANKS1B was associated with psychiatric phenotypes in genome-wide studies.•Here we behaviorally characterize a knockout (KO) for the murine ortholog…”
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9
Postmortem Alzheimer's Disease Hippocampi Show Oxidative Phosphorylation Gene Expression Opposite that of Isolated Pyramidal Neurons
Published in Journal of Alzheimer's disease (01-01-2015)“…Causes of initiation and progression of sporadic Alzheimer's disease (sAD) are likely multiple and include impairment of mitochondrial bioenergetics. We…”
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10
Profile of minocycline neuroprotection in bilirubin-induced auditory system dysfunction
Published in Brain research (12-01-2011)“…Abstract Excessive hyperbilirubinemia in human neonates can cause permanent dysfunction of the auditory system, as assessed with brainstem auditory evoked…”
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11
Albumin administration protects against bilirubin-induced auditory brainstem dysfunction in Gunn rat pups
Published in Liver international (01-11-2013)“…Background Free bilirubin (Bf), the unbound fraction of unconjugated bilirubin (UCB), can induce neurotoxicity, including impairment of the auditory system,…”
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12
In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation
Published in DNA repair (01-05-2009)“…A homozygous H493R mutation in the active site of tyrosyl-DNA phosphodiesterase (TDP1) has been implicated in hereditary spinocerebellar ataxia with axonal…”
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13
Minocycline blocks acute bilirubin-induced neurological dysfunction in jaundiced Gunn rats
Published in Neonatology (Basel, Switzerland) (01-01-2007)“…Extreme hyperbilirubinemia is treated with double volume exchange transfusion, which may take hours to commence. A neuroprotective agent that could be…”
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14
A novel stereotaxic apparatus for neuronal recordings in awake head-restrained rats
Published in Journal of neuroscience methods (15-05-2011)“…► Novel stereotaxic positioner and head holder restraint system for rats ► Avoids the standard requirements for ear bars and a mouth piece ► Permits head…”
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15
Repeated mild brain injuries result in cognitive impairment in B6C3F1 mice
Published in Journal of neurotrauma (01-04-2002)“…Experimental investigations of single mild brain injury (SMI) show relatively little resultant cognitive impairment. However, repeated mild brain injuries…”
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16
Quantification of gait in dystonic Gunn rats
Published in Journal of neuroscience methods (15-06-2009)“…Spontaneously jaundiced Gunn rats exposed to sulfadimethoxine develop bilirubin encephalopathy (kernicterus) with hearing loss and dystonia, closely resembling…”
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17
NMDA channel antagonist MK-801 does not protect against bilirubin neurotoxicity
Published in Neonatology (Basel, Switzerland) (01-01-2007)“…Bilirubin encephalopathy or kernicterus is a potentially serious complication of neonatal hyperbilirubinemia. The mechanism of bilirubin-induced neurotoxicity…”
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18
Biliverdin-induced brainstem auditory evoked potential abnormalities in the jaundiced Gunn rat
Published in Brain research (30-08-2006)“…Brainstem auditory evoked potential (BAEP) abnormalities occur in jaundiced Gunn rats given sulfadimethoxine to displace bilirubin bound to serum albumin,…”
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19
Induced mitochondrial failure in the feline brain: implications for understanding acute post-traumatic metabolic events
Published in Brain research (20-07-2001)“…Objective: Recently, evidence has become available implicating mitochondrial failure as a crucial factor in the pathogenesis of acute brain damage following…”
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20
Chronic ethanol consumption transiently reduces adult neural progenitor cell proliferation
Published in Brain research (11-06-2004)“…Adult neural stem/progenitor cells proliferate throughout the life of the animal in the subependymal zone and the subgranular zone of the dentate gyrus (DG)…”
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