Search Results - "Rice, Andrew P."
-
1
The HIV-1 Tat Protein: Mechanism of Action and Target for HIV-1 Cure Strategies
Published in Current pharmaceutical design (01-01-2017)“…The general mechanism involved in Tat activation of RNA Polymerase II (RNAP II) elongation of the integrated HIV-1 was elucidated over 20 years ago. This…”
Get more information
Journal Article -
2
Emerging Theme: Cellular PDZ Proteins as Common Targets of Pathogenic Viruses
Published in Journal of Virology (01-11-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
3
miR-198 inhibits HIV-1 gene expression and replication in monocytes and its mechanism of action appears to involve repression of cyclin T1
Published in PLoS pathogens (01-01-2009)“…Cyclin T1 is a regulatory subunit of a general RNA polymerase II elongation factor known as P-TEFb. Cyclin T1 is also required for Tat transactivation of HIV-1…”
Get full text
Journal Article -
4
Regulation of Cyclin T1 and HIV-1 Replication by MicroRNAs in Resting CD4+ T Lymphocytes
Published in Journal of Virology (01-03-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
5
Unexpected Mutations in HIV-1 That Confer Resistance to the Tat Inhibitor Didehydro-Cortistatin A
Published in mBio (09-07-2019)“…Didehydro-cortistatin A (dCA) is a human immunodeficiency virus type 1 (HIV-1) Tat inhibitor that functions by selectively binding to the RNA binding domain of…”
Get full text
Journal Article -
6
Cyclin T1 and CDK9 T-Loop Phosphorylation Are Downregulated during Establishment of HIV-1 Latency in Primary Resting Memory CD4+ T Cells
Published in Journal of Virology (01-01-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
7
The Avian Influenza Virus NS1 ESEV PDZ Binding Motif Associates with Dlg1 and Scribble To Disrupt Cellular Tight Junctions
Published in Journal of Virology (01-10-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
8
Subversion of Cell Cycle Regulatory Mechanisms by HIV
Published in Cell host & microbe (10-06-2015)“…To establish a productive infection, HIV-1 must counteract cellular innate immune mechanisms and redirect cellular processes toward viral replication. Recent…”
Get full text
Journal Article -
9
The influenza A virus protein NS1 displays structural polymorphism
Published in Journal of virology (01-04-2014)“…NS1 of influenza A virus is a potent antagonist of host antiviral interferon responses. This multifunctional protein with two distinctive domains, an…”
Get full text
Journal Article -
10
Identification of celastrol as a novel HIV-1 latency reversal agent by an image-based screen
Published in PloS one (29-04-2021)“…Although current antiretroviral therapies (ART) are successful in controlling HIV-1 infection, a stable viral reservoir reactivates when ART is discontinued…”
Get full text
Journal Article -
11
Mining the human complexome database identifies RBM14 as an XPO1-associated protein involved in HIV-1 Rev function
Published in Journal of virology (01-04-2015)“…By recruiting the host protein XPO1 (CRM1), the HIV-1 Rev protein mediates the nuclear export of incompletely spliced viral transcripts. We mined data from the…”
Get full text
Journal Article -
12
The ESEV PDZ-Binding Motif of the Avian Influenza A Virus NS1 Protein Protects Infected Cells from Apoptosis by Directly Targeting Scribble
Published in Journal of Virology (01-11-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
13
Epstein-Barr virus BART9 miRNA modulates LMP1 levels and affects growth rate of nasal NK T cell lymphomas
Published in PloS one (10-11-2011)“…Nasal NK/T cell lymphomas (NKTCL) are a subset of aggressive Epstein-Barr virus (EBV)-associated non-Hodgkin's lymphomas. The role of EBV in pathogenesis of…”
Get full text
Journal Article -
14
Regulation of interferon-β by MAGI-1 and its interaction with influenza A virus NS1 protein with ESEV PBM
Published in PloS one (20-07-2012)“…The NS1 protein from avian influenza A viruses contains a PDZ binding motif (PBM) at its carboxyl terminus with the consensus sequence ESEV. The ESEV PBM…”
Get full text
Journal Article -
15
Serum IgG anti-SARS-CoV-2 Binding Antibody Level Is Strongly Associated With IgA and Functional Antibody Levels in Adults Infected With SARS-CoV-2
Published in Frontiers in immunology (08-10-2021)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in December 2019 in Wuhan, China, and then rapidly spread causing an…”
Get full text
Journal Article -
16
Characterization of Cdk9 T-loop phosphorylation in resting and activated CD4+ T lymphocytes
Published in Journal of leukocyte biology (01-12-2009)“…Low levels of Cdk9 T‐loop autophosphorylation in quiescent CD4+ T lymphocytes may limit RNA polymerase II elongation. The cellular kinase complex P‐TEFb is…”
Get full text
Journal Article -
17
Pressure Catalyzed Bond Dissociation in an Anthracene Cyclophane Photodimer
Published in Journal of the American Chemical Society (02-05-2012)“…The anthracene cyclophane bis-anthracene (BA) can undergo a [4 + 4] photocycloaddition reaction that results in a photodimer with two cyclobutane rings. We…”
Get full text
Journal Article -
18
Regulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells
Published in Virology journal (20-02-2019)“…The regulatory cyclin, Cyclin T1 (CycT1), is a host factor essential for HIV-1 replication in CD4 T cells and macrophages. The importance of CycT1 and the…”
Get full text
Journal Article -
19
Phosphatase PPM1A negatively regulates P-TEFb function in resting CD4T+ T cells and inhibits HIV-1 gene expression
Published in Retrovirology (22-06-2012)“…Doc number: 52 Abstract Background: Processive elongation of the integrated HIV-1 provirus is dependent on recruitment of P-TEFb by the viral Tat protein to…”
Get full text
Journal Article -
20
Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections
Published in mBio (15-05-2018)“…Viral pneumonias cause profound worldwide morbidity, necessitating novel strategies to prevent and treat these potentially lethal infections. Stimulation of…”
Get full text
Journal Article