Search Results - "Riccobono, Diane"

The Protein Kinase A Inhibitor KT5720 Prevents Endothelial Dysfunctions Induced by High-Dose Irradiation by Boittin, François-Xavier, Guitard, Nathalie, Toth, Maeliss, Riccobono, Diane, Théry, Hélène, Bobe, Régis

“…High-dose irradiation can trigger numerous endothelial dysfunctions, including apoptosis, the overexpression of adhesion molecules, and alteration of adherens…”
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Autologous adipocyte derived stem cells favour healing in a minipig model of cutaneous radiation syndrome by Forcheron, Fabien, Agay, Diane, Scherthan, Harry, Riccobono, Diane, Herodin, Francis, Meineke, Viktor, Drouet, Michel

“…Cutaneous radiation syndrome (CRS) is the delayed consequence of localized skin exposure to high doses of ionizing radiation. Here we examined for the first…”
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Nano-Architecture of Persistent Focal DNA Damage Regions in the Minipig Epidermis Weeks after Acute γ-Irradiation by Scherthan, Harry, Geiger, Beatrice, Ridinger, David, Müller, Jessica, Riccobono, Diane, Bestvater, Felix, Port, Matthias, Hausmann, Michael

“…Exposure to high acute doses of ionizing radiation (IR) can induce cutaneous radiation syndrome. Weeks after such radiation insults, keratinocyte nuclei of the…”
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In Situ Identification of Both IL-4 and IL-10 Cytokine-Receptor Interactions during Tissue Regeneration by Nikovics, Krisztina, Favier, Anne-Laure, Rocher, Mathilde, Mayinga, Céline, Gomez, Johanna, Dufour-Gaume, Frédérique, Riccobono, Diane

“…Cytokines secreted by individual immune cells regulate tissue regeneration and allow communication between various cell types. Cytokines bind to cognate…”
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TRPV4 channel activation induces the transition of venous and arterial endothelial cells toward a pro‐inflammatory phenotype by Beddek, Kathia, Raffin, Florent, Borgel, Delphine, Saller, François, Riccobono, Diane, Bobe, Régis, Boittin, François‐Xavier

“…The Transient Receptor Potential Vanilloid 4 (TRPV4) of endothelial cells contributes to many important functions including the regulation of Ca2+ homeostasis,…”
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MSC-Derived Extracellular Vesicles: New Emergency Treatment to Limit the Development of Radiation-Induced Hematopoietic Syndrome? by Cavallero, Sophie, Riccobono, Diane, Drouet, Michel, François, Sabine

“…ABSTRACTNuclear accidents or acts of terrorism involving radioactive sources might lead to mass casualties irradiation. The hematopoietic system is one of the…”
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Hybridization‐chain‐reaction is a relevant method for in situ detection of M2d‐like macrophages in a mini‐pig model by Nikovics, Krisztina, Morin, Halima, Riccobono, Diane, Bendahmane, Abdelhafid, Favier, Anne‐Laure

“…Macrophages are a heterogeneous population of cells with an important role in innate immunity and tissue regeneration. Based on in vitro experiments,…”
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Comments on "Cellular Therapies for Treatment of Radiation Injury after a Mass Casualty Incident" (Radiat Res 2017; 188:242-45) by Drouet, Michel, Riccobono, Diane, François, Sabine

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Comparison of Three Antagonists of Hedgehog Pathway to Promote Skeletal Muscle Regeneration after High Dose Irradiation by Graziosi, Emmanuelle Rota, François, Sabine, Nasser, Farah, Gauthier, Michel, Oger, Myriam, Favier, Anne-Laure, Drouet, Michel, Jullien, Nicolas, Riccobono, Diane

“…The current geopolitical context has brought the radiological nuclear risk to the forefront of concerns. High-dose localized radiation exposure leads to the…”
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Characterization of macrophages, giant cells and granulomas during muscle regeneration after irradiation by Nikovics, Krisztina, Favier, Anne-Laure, Barbier, Laure, Drouet, Michel, Riccobono, Diane

“…•ASC cells play an important role in improving tissue regeneration.•Majority of the Macrophages show strong IL-6 expression.•The CD4+ cells produce IL-1β…”
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Comments on “Cellular Therapies for Treatment of Radiation Injury after a Mass Casualty Incident” (Radiat Res 2017; 188:242-45) by Drouet, Michel, Riccobono, Diane, François, Sabine

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The immunosuppressant drug Cyclosporin A aggravates irradiation effects in endothelial cells by Boittin, François-Xavier, Beddek, Kathia, Thery, Hélène, Pateux, Jérome, Cosler, Guillaume, Riccobono, Diane, Drouet, Michel, Bobe, Régis

“…The immunosuppressant drug Cyclosporin A (CsA) has been widely used to prevent the development of Graft-versus-Host Disease (GvHD) that can occur after…”
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French Policies for Victim Management During Mass Radiological Accidents/Attacks by Riccobono, Diane, Valente, Marco, Drouet, Michel, Calamai, Franck, Abriat, Amandine

“…ABSTRACTIn the current international context, emergency medical services have to be prepared for chemical, biological, radiological, and nuclear events…”
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Validation of genes for H-ARS severity prediction in leukemia patients - interspecies comparison, challenges, and promises by Schwanke, Daniel, Valente, Marco, Ostheim, Patrick, Schüle, Simone, Bobyk, Laure, Drouet, Michel, Riccobono, Diane, Magné, Nicolas, Daguenet, Elisabeth, Stewart, Samantha Jo, Muhtadi, Razan, Port, Matthias, Abend, Michael

“…In a previous baboon-study, a total of 29 genes were identified for clinical outcome prediction of the hematologic, acute, radiation, syndrome (H-ARS)…”
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Non-Specific Binding, a Limitation of the Immunofluorescence Method to Study Macrophages In Situ by Sicherre, Emma, Favier, Anne-Laure, Riccobono, Diane, Nikovics, Krisztina

“…Advances in understanding tissue regenerative mechanisms require the characterization of in vivo macrophages as those play a fundamental role in this process…”
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A New Murine Highly Localized High-Dose Muscle Radiation Model as a Tool to Develop Innovative Countermeasures to Treat Radio-Induced Muscular Lesions by Nicolas Jullien, Emmanuelle Rota Graziosi, Michel Gauthier, Michel Drouet, Sabine Francois, Diane Riccobono

“…Acute localized irradiation accidents may evolve into a musculocutaneous radiation-induced syndrome that leaves a significant underlying muscle defect despite…”
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Contribution of INTRAMUSCULAR Autologous Adipose Tissue-Derived Stem Cell Injections to Treat Cutaneous Radiation Syndrome: Preliminary Results by Riccobono, Diane, Agay, Diane, François, Sabine, Scherthan, Harry, Drouet, Michel, Forcheron, Fabien

“…ABSTRACTCutaneous radiation syndrome caused by high dose located irradiation is characterized by delayed symptoms, incomplete wound healing, and poor…”
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First Insights Into the M2 Inflammatory Response After Adipose-Tissue-Derived Stem Cell Injections in Radiation-Injured Muscles by Riccobono, Diane, Nikovics, Krisztina, François, Sabine, Favier, Anne-Laure, Jullien, Nicolas, Schrock, Gerrit, Scherthan, Harry, Drouet, Michel

“…ABSTRACTThe cutaneous radiation syndrome is the clinical consequence of local high-dose irradiation. It is characterized by extensive inflammation, necrosis,…”
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Application of Adipocyte-Derived Stem Cells in Treatment of Cutaneous Radiation Syndrome by Riccobono, Diane, Agay, Diane, Scherthan, Harry, Forcheron, Fabien, Vivier, Mylène, Ballester, Bruno, Meineke, Viktor, Drouet, Michel

“…ABSTRACTCutaneous radiation syndrome caused by local high dose irradiation is characterized by delayed outcome and incomplete healing. Recent therapeutic…”
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Bringing Radiation Exposures and Associated Health Risks into Perspective—Development of an App by Abend, Michael, Stricklin, Daniela, Flaig, Nicole, Badie, Christophe, Drouet, Michel, Foster, Crawford, Janiak, Marek K., Kuipers, Tjerk, Lista, Florigio, Nowosielska, Ewa M., Riccobono, Diane, de Sanctis, Stefania, Franchini, Valeria, Tichy, Ales, Port, Matthias

“…ABSTRACTThe NATO HFM 291 research task group (RTG) on “Ionizing Radiation Bioeffects and Countermeasures” represents a group of scientists from military and…”
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