Search Results - "Ricaurte, G.A"

Dopamine uptake blockers protect against the dopamine depleting effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse striatum by Ricaurte, G A, Langston, J W, DeLanney, L E, Irwin, I, Brooks, J D

“…1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), a recently described neurotoxin, produces a marked dopamine (DA) depletion in the mouse striatum. In this…”
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Toxicodynamics and long-term toxicity of the recreational drug, 3,4-methylenedioxymethamphetamine (MDMA, ‘Ecstasy’) by Ricaurte, G.A, McCann, U.D, Szabo, Z, Scheffel, U

“…The recreational drug, (±)3,4-methylenedioxymethamphetamine (MDMA, ‘Ecstasy’), is a potent serotonin (5-HT) neurotoxin in animals. Whether humans who use MDMA…”
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Fluoxetine increases long-lasting neostriatal dopamine depletion after administration of d-methamphetamine and d-amphetamine by Ricaurte, G A, Fuller, R W, Perry, K W, Seiden, L S, Schuster, C R

“…Repeated administration of large doses of d-methamphetamine produce long-lasting depletion of brain dopamine (DA) and serotonin (5-HT), as well as persistent…”
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Use of MDMA and other illicit drugs by young adult males in northern Spain. A five-year study by Bobes, J, Sáiz, P A, González, M P, Bascarán, M T, Bousoño, M, Ricaurte, G A, McCann, U D

“…To measure the prevalence of 3,4-methylenedioxymethamphetamine (MDMA) and other drug use in young males entering compulsory military service in Asturias…”
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Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration by Ricaurte, G A, DeLanney, L E, Irwin, I, Langston, J W

“…This study compared the toxic effects of oral versus subcutaneous and single versus multiple doses of 3,4-methylenedioxymethamphetamine (MDMA) on central…”
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Distinct morphologic classes of serotonergic axons in primates exhibit differential vulnerability to the psychotropic drug 3,4-methylenedioxymethamphetamine by Wilson, M A, Ricaurte, G A, Molliver, M E

“…Immunohistochemical methods were used to analyse the distribution and morphology of serotonergic axons in normal macaque monkeys and in monkeys given…”
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Aging and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced degeneration of dopaminergic neurons in the substantia nigra by Ricaurte, G A, Irwin, I, Forno, L S, DeLanney, L E, Langston, E, Langston, J W

“…This study assessed the influence of aging on substantia nigra degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Extensive neuronal…”
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Dexfenfluramine neurotoxicity in brains of non-human primates by Ricaurte, G A, Molliver, M E, Martello, M B, Katz, J L, Wilson, M A, Martello, A L

“…Dexfenfluramine, a drug prescribed for appetite suppression, was evaluated in non-human primates for its potential to produce toxic effects on brain serotonin…”
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[11C]WIN-35,428 PET Imaging Reveals Decreased Dopamine Transporter Density in Abstinent Methamphetamine Users by Wong, D.F., McCann, U.D., Yokoi, F., Villemagne, V., Dannals, R.F., Ricaurte, G.A.

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Dopamine nerve terminal degeneration produced by high doses of methylamphetamine in the rat brain by Ricaurte, G A, Guillery, R W, Seiden, L S, Schuster, C R, Moore, R Y

“…Numerous recent studies indicate that when amphetamines are administered continuously or in high doses, they exert long-lasting toxic effects on dopamine (DA)…”
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Repeated administration of MDMA causes transient down-regulation of serotonin 5-HT2 receptors by Scheffel, U, Lever, J R, Stathis, M, Ricaurte, G A

“…The present study examined short- and long-term effects of MDMA (3,4-methylene-dioxymethamphetamine) on serotonin (5-HT2 and 5-HT1c) receptors in the brain of…”
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5-Hydroxyindoleacetic acid in cerebrospinal fluid reflects serotonergic damage induced by 3,4-methylenedioxymethamphetamine in CNS of non-human primates by Ricaurte, G A, DeLanney, L E, Wiener, S G, Irwin, I, Langston, J W

“…This study examined whether 5-hydroxyindoleacetic acid (5-HIAA) in cerebrospinal fluid (CSF) could be used to detect serotonergic damage induced by…”
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Further evidence that amphetamines produce long-lasting dopamine neurochemical deficits by destroying dopamine nerve fibers by Ricaurte, G A, Seiden, L S, Schuster, C R

“…Methamphetamine and amphetamine were continuously administered to rats for 3 days by means of subcutaneously implanted osmotic minipumps. The total daily dose…”
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Older dopaminergic neurons do not recover from the effects of MPTP by Ricaurte, G A, DeLanney, L E, Irwin, I, Langston, J W

“…Recent studies have shown that dopaminergic neurons in young mature mice recover fully from toxic injury induced by MPTP. The aim of the present study was to…”
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Orally administered MDMA causes a long-term depletion of serotonin in rat brain by Finnegan, K T, Ricaurte, G A, Ritchie, L D, Irwin, I, Peroutka, S J, Langston, J W

“…Recent studies suggest that 3,4-methylenedioxymethylamphetamine (MDMA), when administered subcutaneously, is toxic to central serotonergic neurons in rats…”
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3,4-Methylenedioxyethylamphetamine (MDE), a novel analogue of MDMA, produces long-lasting depletion of serotonin in the rat brain by Ricaurte, G A, Finnegan, K F, Nichols, D E, DeLanney, L E, Irwin, I, Langston, J W

“…The present study was carried out to asses possible toxic effects of 3,4-methylenedioxyethylamphetamine (MDE) on serotonergic, dopaminergic or noradrenergic…”
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Neurochemical similarities between d,l-cathinone and d-amphetamine by Wagner, G C, Preston, K, Ricaurte, G A, Schuster, C R, Seiden, L S

“…Cathinone, the principal alkaloid of Khat, was compared to the psychomotor stimulant d-amphetamine on a number of neurochemical measures. Like d-amphetamine,…”
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Evaluation of the neurotoxic potential of N,N-dimethylamphetamine: an illicit analog of methamphetamine by Ricaurte, G A, DeLanney, L E, Irwin, I, Witkin, J M, Katz, J L, Langston, J W

“…The purpose of this study was to evaluate the neurotoxic potential of N,N-dimethylamphetamine (N,N-DMA), a controlled substance analog that has recently…”
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Nerve terminal degeneration after a single injection of D-amphetamine in iprindole-treated rats: relation to selective long-lasting dopamine depletion by Ricaurte, G A, Guillery, R W, Seiden, L S, Schuster, C R

“…A single injection of D-amphetamine has recently been shown to produce long-lasting dopamine (DA) deficits in rats pretreated with iprindole, an agent which…”
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The dopamine-depleting effect of 6-hydroxydopamine does not increase with aging by Ricaurte, G A, DeLanney, L E, Finnegan, K T, Irwin, I, Langston, J W

“…The dopamine-depleting effects of intracerebroventricularly administered 6-hydroxydopamine (6-OHDA) were studied in young mature (6-8 weeks), older (8-12…”
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