Search Results - "Ribon, Matthieu"
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Modifying macrophages at the periphery has the capacity to change microglial reactivity and to extend ALS survival
Published in Nature neuroscience (01-11-2020)“…Microglia and peripheral macrophages have both been implicated in amyotrophic lateral sclerosis (ALS), although their respective roles have yet to be…”
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2
Extracellular Chromatin Triggers Release of Soluble CEACAM8 Upon Activation of Neutrophils
Published in Frontiers in immunology (14-06-2019)“…Increased concentrations of extracellular chromatin are observed in cancer, sepsis, and inflammatory autoimmune diseases like systemic lupus erythematosus…”
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3
The mouse dendritic cell marker CD11c is down-regulated upon cell activation through Toll-like receptor triggering
Published in Immunobiology (1979) (01-01-2013)“…Abstract Dendritic cells (DC) play a key role in regulating immune responses and are the best professional antigen-presenting cells. Two major DC populations…”
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Increased Concentrations of Circulating Soluble MHC Class I-Related Chain A (sMICA) and sMICB and Modulation of Plasma Membrane MICA Expression: Potential Mechanisms and Correlation With Natural Killer Cell Activity in Systemic Lupus Erythematosus
Published in Frontiers in immunology (03-05-2021)“…Systemic lupus erythematosus (SLE) is a severe autoimmune disease of unknown etiology. The major histocompatibility complex (MHC) class I-related chain A…”
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Primary blood neutrophils express a functional cell surface Toll‐like receptor 9
Published in European journal of immunology (01-08-2013)“…Polymorphonuclear leukocytes (PMNs) represent one of the first lines of defense against pathogens. TLR9 is normally expressed in endosomes/lysosomes where it…”
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6
Neutrophil extracellular traps exert both pro- and anti-inflammatory actions in rheumatoid arthritis that are modulated by C1q and LL-37
Published in Journal of autoimmunity (01-03-2019)“…Neutrophil extracellular traps (NET), produced by activated polymorphonuclear neutrophils (PMN), are supposed to play a role in the pathogenesis of rheumatoid…”
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TLR9 independent interferon α production by neutrophils on NETosis in response to circulating chromatin, a key lupus autoantigen
Published in Annals of the rheumatic diseases (01-12-2014)“…Interferon (IFN) α is a key immunoregulatory cytokine secreted by activated plasmacytoid dendritic cells (PDC) that constitute less than 1% of leucocytes. IFNα…”
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Evidence for glutamine synthetase function in mouse spinal cord oligodendrocytes
Published in Glia (01-12-2021)“…Glutamine synthetase (GS) is a key enzyme that metabolizes glutamate into glutamine. While GS is highly enriched in astrocytes, expression in other glial…”
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Deletion of the inflammatory S100-A9/MRP14 protein does not influence survival in hSOD1G93A ALS mice
Published in Neurobiology of aging (01-05-2021)“…Neuroinflammation is a hallmark of Amyotrophic Lateral Sclerosis (ALS) in hSOD1G93A mouse models where microglial cells contribute to the progressive motor…”
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Deletion of the inflammatory S100-A9/MRP14 protein does not influence survival in hSOD1 G93A ALS mice
Published in Neurobiology of aging (01-05-2021)“…Neuroinflammation is a hallmark of Amyotrophic Lateral Sclerosis (ALS) in hSOD1 mouse models where microglial cells contribute to the progressive motor neuron…”
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Effect of ultrasound-mediated blood-spinal cord barrier opening on survival and motor function in females in an amyotrophic lateral sclerosis mouse modelResearch in context
Published in EBioMedicine (01-08-2024)“…Background: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by a progressive loss of motor neurons. The limited efficacy…”
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Effect of ultrasound-mediated blood-spinal cord barrier opening on survival and motor function in females in an amyotrophic lateral sclerosis mouse model
Published in EBioMedicine (01-08-2024)“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by a progressive loss of motor neurons. The limited efficacy of recent…”
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13
Primary blood neutrophils express a functional cell surface T oll‐like receptor 9
Published in European journal of immunology (01-08-2013)“…Polymorphonuclear leukocytes ( PMN s) represent one of the first lines of defense against pathogens. TLR 9 is normally expressed in endosomes/lysosomes where…”
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