Search Results - "Ribeiro, Orquidea"
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Unexpected structures formed by the kinase RET C634R mutant extracellular domain suggest potential oncogenic mechanisms in MEN2A
Published in The Journal of biological chemistry (01-10-2022)“…The RET receptor tyrosine kinase plays a pivotal role in cell survival, proliferation, and differentiation, and its abnormal activation leads to cancers…”
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2
PTCHD1 Binds Cholesterol but Not Sonic Hedgehog, Suggesting a Distinct Cellular Function
Published in International journal of molecular sciences (31-01-2023)“…Deleterious mutations in the X-linked Patched domain-containing 1 (PTCHD1) gene may account for up to 1% of autism cases. Despite this, the PTCHD1 protein…”
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3
Functional and structural asymmetry suggest a unifying principle for catalysis in membrane-bound pyrophosphatases
Published in EMBO reports (13-02-2024)“…Membrane-bound pyrophosphatases (M-PPases) are homodimeric primary ion pumps that couple the transport of Na + - and/or H + across membranes to the hydrolysis…”
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4
Burnout in intensive care units - a consideration of the possible prevalence and frequency of new risk factors: a descriptive correlational multicentre study
Published in BMC anesthesiology (31-10-2013)“…The provision of Intensive Care (IC) can lead to a health care provider's physical, psychological and emotional exhaustion, which may develop into burnout. We…”
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5
A Class of Rigid Linker-bearing Glucosides for Membrane Protein Structural Study
Published in Chemical science (Cambridge) (01-03-2016)“…Membrane proteins are amphipathic bio-macromolecules incompatible with the polar environments of aqueous media. Conventional detergents encapsulate the…”
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6
Reading the Aftermath of Portuguese Colonialism: The Retorno in the Written Media of the 21st Century
Published in Societies (Basel, Switzerland) (01-11-2022)“…The purpose of this work is to undertake an exploratory pilot study on the multiplicity of texts that strive to write or analyse the memories of the displaced…”
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A population-based nationwide cross-sectional study on preventive health services utilization in Portugal--what services (and frequencies) are deemed necessary by patients?
Published in PloS one (21-11-2013)“…Most of the strategies to induce a more rational use of preventive health services are oriented to the medical side of the doctor-patient relationship…”
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The impact of healthcare-associated infection on mortality: failure in clinical recognition is related with inadequate antibiotic therapy
Published in PloS one (08-03-2013)“…To understand if clinicians can tell apart patients with healthcare-associated infections (HCAI) from those with community-acquired infections (CAI) and to…”
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9
Tandem malonate-based glucosides (TMGs) for membrane protein structural studies
Published in Scientific reports (21-06-2017)“…High-resolution membrane protein structures are essential for understanding the molecular basis of diverse biological events and important in drug development…”
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10
Patients' estimations of the importance of preventive health services: a nationwide, population-based cross-sectional study in Portugal
Published in BMJ open (05-10-2016)“…To determine, in the context of primary care preventive health services, the level of importance that Portuguese patients attribute to different preventive…”
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11
Nzinga Mbandi: from story to myth
Published in Journal of Science and Technology of the Arts (01-01-2019)“…The figure of Queen Nzinga Mbandi continues to be appreciated in fictional and/or historical narratives as a myth of postcolonial Angolan identity, allowing a…”
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12
Navigating Colonialism through Sports
Published in Motricidade (01-12-2022)“…"Navigating colonialism through Sports in Portuguese Africa" aims to present a brief review of literature on the importance of sports in the African…”
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13
Differences in microbiological profile between community-acquired, healthcare-associated and hospital-acquired infections
Published in Acta medica portuguesa (01-07-2013)“…Microbiological profiles were analysed and compared for intra-abdominal, urinary, respiratory and bloodstream infections according to place of acquisition:…”
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14
REPRESENTAÇÕES DA MULHER NAS CRÓNICAS DE JÚLIO DANTAS NA REVISTA ILUSTRAÇÃO PORTUGUESA (1913-1916)
Published in Prâksis (23-08-2023)“…Entre abril de 1913 e maio de 1916, Júlio Dantas publicou 129 crónicas na 2ª série da Ilustração Portuguesa. Iniciada em fevereiro 1906, a 2ª série assumia-se…”
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15
Additional risk factors for infection by multidrug-resistant pathogens in healthcare-associated infection: a large cohort study
Published in BMC infectious diseases (26-12-2012)“…There is a lack of consensus regarding the definition of risk factors for healthcare-associated infection (HCAI). The purpose of this study was to identify…”
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Influence of vasopressor agent in septic shock mortality. Results from the Portuguese Community-Acquired Sepsis Study (SACiUCI study)
Published in Critical care medicine (01-02-2009)“…OBJECTIVE:Guidelines for the adrenergic support of septic shock are controversial. In patients with community-acquired septic shock, we assessed the impact of…”
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17
Understanding posttraumatic stress disorder-related symptoms after critical care: The early illness amnesia hypothesis
Published in Critical care medicine (01-10-2008)“…OBJECTIVE:To assess the factual and delusional memories reported by intensive care unit survivors and its relationship with the development of Posttraumatic…”
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Reducing mortality in severe sepsis with the implementation of a core 6-hour bundle: results from the Portuguese community-acquired sepsis study (SACiUCI study)
Published in Critical care (London, England) (01-01-2010)“…To evaluate the impact of compliance with a core version of the Surviving Sepsis Campaign 6-hour bundle on 28 days mortality. Cohort, multi-centre, prospective…”
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Ethical decision making in intensive care units: a burnout risk factor? Results from a multicentre study conducted with physicians and nurses
Published in Journal of medical ethics (01-02-2014)“…Background Ethical decision making in intensive care is a demanding task. The need to proceed to ethical decision is considered to be a stress factor that may…”
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20
De-silencing the Past: Postmemory and Reparative Writing in Selected Works by African-American Women Writers
Published in Ex aequo (Oeiras, Portugal) (01-06-2023)“…Abstract Marianne Hirsch’s concept of postmemory implies a connection with the past that is indirect, mediated by the imagination and desire, transmitted to…”
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