Search Results - "Ribeiro, M J"

Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites by Ribeiro, António J M, Holliday, Gemma L, Furnham, Nicholas, Tyzack, Jonathan D, Ferris, Katherine, Thornton, Janet M

“…Abstract M-CSA (Mechanism and Catalytic Site Atlas) is a database of enzyme active sites and reaction mechanisms that can be accessed at…”
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Application of quantum mechanics/molecular mechanics methods in the study of enzymatic reaction mechanisms by Sousa, Sérgio Filipe, Ribeiro, António J. M., Neves, Rui P. P., Brás, Natércia F., Cerqueira, Nuno M. F. S. A., Fernandes, Pedro A., Ramos, Maria João

“…Quantum mechanics/molecular mechanics (QM/MM) methods offer a very appealing option for the computational study of enzymatic reaction mechanisms, by separating…”
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Unique Triphenylphosphonium Derivatives for Enhanced Mitochondrial Uptake and Photodynamic Therapy by Hu, Zhang, Sim, Ying, Kon, Oi Lian, Ng, Wai Har, Ribeiro, António J. M, Ramos, Maria J, Fernandes, Pedro A, Ganguly, Rakesh, Xing, Bengang, García, Felipe, Yeow, Edwin K. L

“…In this study, unique methyl-functionalized derivatives (T*PP+) of the drug carrier triphenylphosphonium (TPP+) that exhibit significant enhancement of the…”
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An insight into the sialome, mialome and virome of the horn fly, Haematobia irritans by Ribeiro, J M, Debat, Humberto Julio, Boiani, M, Ures, X, Rocha, S, Breijo, M

“…The horn fly (Haematobia irritans) is an obligate blood feeder that causes considerable economic losses in livestock industries worldwide. The control of this…”
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The Catalytic Mechanism of HIV‑1 Integrase for DNA 3′-End Processing Established by QM/MM Calculations by Ribeiro, António J. M, Ramos, Maria J, Fernandes, Pedro A

“…The development of HIV-1 integrase (INT) inhibitors has been hampered by incomplete structural and mechanistic information. Despite the efforts made to…”
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Distribution of grey matter atrophy in Huntington’s disease patients: A combined ROI-based and voxel-based morphometric study by Douaud, G., Gaura, V., Ribeiro, M.-J., Lethimonnier, F., Maroy, R., Verny, C., Krystkowiak, P., Damier, P., Bachoud-Levi, A.-C., Hantraye, P., Remy, P.

“…The striatum, a subcortical structure, is the principal target of the neurodegenerative process in Huntington’s disease (HD). The measurement of striatal…”
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New Approach For Simvastatin As An Antibacterial: Synergistic Effect With Bio-Synthesized Silver Nanoparticles Against Multidrug-Resistant Bacteria by Figueiredo, E P, Ribeiro, J M, Nishio, E K, Scandorieiro, S, Costa, A F, Cardozo, V F, Oliveira, A G, Durán, N, Panagio, L A, Kobayashi, Rkt, Nakazato, G

“…Multidrug-resistant bacteria such as extended-spectrum beta-lactamase (ESBL), Enterobacteriaceae, and methicillin-resistant (MRSA) pose a challenge to the…”
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A multidisciplinary study of patients with early-onset PD with and without parkin mutations by LOHMANN, E, THOBOIS, S, POLLAK, P, AGID, Y, BRICE, A, LESAGE, S, BROUSSOLLE, E, TEZENAS DU MONTCEL, S, RIBEIRO, M.-J, REMY, P, PELISSOLO, A, DUBOIS, B, MALLET, L

“…To establish phenotype-genotype correlations in early-onset Parkinson disease (EOPD), we performed neurologic, neuropsychological, and psychiatric evaluations…”
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Benchmarking of DFT Functionals for the Hydrolysis of Phosphodiester Bonds by Ribeiro, António J. M, Ramos, Maria J, Fernandes, Pedro A

“…Phosphodiester bonds are an important chemical component of biological systems, and their hydrolysis and formation reactions are involved in major steps…”
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ABCC8 and KCNJ11 molecular spectrum of 109 patients with diazoxide-unresponsive congenital hyperinsulinism by Bellanné-Chantelot, C, Saint-Martin, C, Ribeiro, M-J, Vaury, C, Verkarre, V, Arnoux, J-B, Valayannopoulos, V, Gobrecht, S, Sempoux, C, Rahier, J, Fournet, J-C, Jaubert, F, Aigrain, Y, Nihoul-Fékété, C, de Lonlay, P

“…Congenital hyperinsulinism (CHI) is characterised by an over secretion of insulin by the pancreatic β-cells. This condition is mostly caused by mutations in…”
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Using mechanism similarity to understand enzyme evolution by Ribeiro, António J. M., Riziotis, Ioannis G., Tyzack, Jonathan D., Borkakoti, Neera, Thornton, Janet M.

“…Enzyme reactions take place in the active site through a series of catalytic steps, which are collectively termed the enzyme mechanism. The catalytic step is…”
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The Catalytic Mechanism of Protein Phosphatase 5 Established by DFT Calculations by Ribeiro, António J. M., Alberto, Marta E., Ramos, Maria J., Fernandes, Pedro A., Russo, Nino

“…In order to elucidate the catalytic mechanism of the Mn–Mn containing serine/threonine protein phosphatase 5 (PP5), we present a density functional theory…”
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Basal ganglia involvement in temporal lobe epilepsy : A functional and morphologic study by BOUILLERET, V, SEMAH, F, CHASSOUX, F, MANTZARIDEZ, M, BIRABEN, A, TREBOSSEN, R, RIBEIRO, M.-J

“…A decrease of [(18)F]fluoro-l-dopa uptake in basal ganglia was recently reported in medically refractory epilepsy. The purpose of this study was to assess the…”
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Synthesis and Hydrolytic Studies on the Air-Stable [(4-CN-PhO)(E)P(μ‑N t Bu)]2 (E = O, S, and Se) Cyclodiphosphazanes by Shi, Yan X, Liang, Rong Z, Martin, Katherine A, Weston, Nicholas, Gonzalez-Calera, Silvia, Ganguly, Rakesh, Li, Yongxin, Lu, Yunpeng, Ribeiro, António J. M, Ramos, Maria J, Fernandes, Pedro A, García, Felipe

“…Reaction of 4-CN-PhOH with [ClP­(μ-N t Bu)]2 (1) (2:1 ratio) in the presence of Et3N produced the functionalized cyclodiphosph­(III/III)­azane…”
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Improving the Biodesulfurization of Crude Oil and Derivatives: A QM/MM Investigation of the Catalytic Mechanism of NADH-FMN Oxidoreductase (DszD) by Sousa, Sérgio F, Sousa, Joana F. M, Barbosa, Ana C. C, Ferreira, Cleide E, Neves, Rui P. P, Ribeiro, António J. M, Fernandes, Pedro A, Ramos, Maria João

“…The development of biocatalytic desulfurization strategies of petroleum and its derivatives could result in more economic alternatives than the widely used…”
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Clinical science, responsibilities and society by Ribeiro, J. M., de Jaegere, P. P. T.

“…The article by van Lavieren et al. concerns an observational study with its inherent and acknowledged limitations (e.g. sample size, inclusion and exclusion…”
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PET evidence for a role of the basal ganglia in patients with ring chromosome 20 epilepsy by BIRABEN, A, SEMAH, F, RIBEIRO, M.-J, DOUAUD, G, REMY, P, DEPAULIS, A

“…Studies in animal models and epileptic patients have suggested that circuits of the basal ganglia may control epileptic seizures and that striatal dopaminergic…”
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A global analysis of function and conservation of catalytic residues in enzymes by Ribeiro, António J.M., Tyzack, Jonathan D., Borkakoti, Neera, Holliday, Gemma L., Thornton, Janet M.

“…The catalytic residues of an enzyme comprise the amino acids located in the active center responsible for accelerating the enzyme-catalyzed reaction. These…”
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Effect of Structural Variation of Dead Trunks on Passalid (Coleoptera: Passalidae) Assemblages in Central Amazonian Campinaranas by Alencar, J B. R., da Fonseca, C R. V., Baccaro, F B., Bento, M M. F., Ribeiro, J M.

“…The present study investigated the occurrence of passalids in dead trunks with structural variations. Trunks were found in areas of white sand forests, locally…”
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Influence of fish oil on ruminal biohydrogenation of C18 unsaturated fatty acids by Wąsowska, I., Maia, M. R. G., Niedźwiedzka, K. M., Czauderna, M., Ramalho Ribeiro, J. M. C., Devillard, E., Shingfield, K. J., Wallace, R. J.

“…Dietary cis-9, trans-11-conjugated linoleic acid (CLA) is generally thought to be beneficial for human health. Fish oil added to ruminant diets increases the…”
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