Search Results - "Ribeiro, José M. C"
-
1
Sialome diversity of ticks revealed by RNAseq of single tick salivary glands
Published in PLoS neglected tropical diseases (13-04-2018)“…Ticks salivate while feeding on their hosts. Saliva helps blood feeding through host anti-hemostatic and immunomodulatory components. Previous transcriptomic…”
Get full text
Journal Article -
2
An Insight into the Sialome of the Lone Star Tick, Amblyomma americanum, with a Glimpse on Its Time Dependent Gene Expression
Published in PloS one (01-07-2015)“…Hard ticks feed for several days or weeks on their hosts. Blood feeding is assisted by tick saliva, which is injected in the host skin regularly, alternating…”
Get full text
Journal Article -
3
A deep insight into the sialotranscriptome of the gulf coast tick, Amblyomma maculatum
Published in PloS one (21-12-2011)“…Saliva of blood sucking arthropods contains compounds that antagonize their hosts' hemostasis, which include platelet aggregation, vasoconstriction and blood…”
Get full text
Journal Article -
4
TickSialoFam (TSFam): A Database That Helps to Classify Tick Salivary Proteins, a Review on Tick Salivary Protein Function and Evolution, With Considerations on the Tick Sialome Switching Phenomenon
Published in Frontiers in cellular and infection microbiology (24-07-2020)“…Tick saliva contains a complex mixture of peptides and non-peptides that counteract their hosts' hemostasis, immunity, and tissue-repair reactions. Recent…”
Get full text
Journal Article -
5
A Deep Insight into the Sialome of Male and Female Aedes aegypti Mosquitoes
Published in PloS one (21-03-2016)“…Only adult female mosquitoes feed on blood, while both genders take sugar meals. Accordingly, several compounds associated with blood feeding (i.e…”
Get full text
Journal Article -
6
PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum
Published in Nature (London) (11-07-2013)“…The malaria parasite Plasmodium falciparum escapes immune detection by expressing one of 60 antigenically distinct var genes at any one time during the course…”
Get full text
Journal Article -
7
A longitudinal transcriptomic analysis from unfed to post-engorgement midguts of adult female Ixodes scapularis
Published in Scientific reports (13-07-2023)“…The hematophagy behavior has evolved independently several times within the Arthropoda phylum. Interestingly, the process of acquiring a blood meal in ticks is…”
Get full text
Journal Article -
8
Revisiting the sialome of the cat flea Ctenocephalides felis
Published in PloS one (17-01-2023)“…The hematophagous behaviour emerged independently in several instances during arthropod evolution. Survey of salivary gland and saliva composition and its…”
Get full text
Journal Article -
9
Tissue- and time-dependent transcription in Ixodes ricinus salivary glands and midguts when blood feeding on the vertebrate host
Published in Scientific reports (13-03-2015)“…Ixodes ricinus is a tick that transmits the pathogens of Lyme and several arboviral diseases. Pathogens invade the tick midgut, disseminate through the…”
Get full text
Journal Article -
10
PfCDPK1 is critical for malaria parasite gametogenesis and mosquito infection
Published in Proceedings of the National Academy of Sciences - PNAS (23-01-2018)“…Efforts to knock out Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) from asexual erythrocytic stage have not been successful, indicating an…”
Get full text
Journal Article -
11
Exploring the transcriptome of immature stages of Ornithodoros hermsi, the soft-tick vector of tick-borne relapsing fever
Published in Scientific reports (30-05-2024)“…Blood-feeding behavior has independently evolved in arthropods multiple times. Unlike hard ticks, soft ticks employ a rapid-feeding strategy for hematophagy,…”
Get full text
Journal Article -
12
An insight into the sialotranscriptome and virome of Amazonian anophelines
Published in BMC genomics (04-03-2019)“…Saliva of mosquitoes contains anti-platelet, anti-clotting, vasodilatory, anti-complement and anti-inflammatory substances that help the blood feeding process…”
Get full text
Journal Article -
13
Human CD117 (cKit)+ innate lymphoid cells have a discrete transcriptional profile at homeostasis and are expanded during filarial infection
Published in PloS one (25-09-2014)“…Since innate lymphoid cells (ILCs) have been found to play a role in the immune response to helminth parasites in rodents, we sought to determine their role in…”
Get full text
Journal Article -
14
Lundep, a sand fly salivary endonuclease increases Leishmania parasite survival in neutrophils and inhibits XIIa contact activation in human plasma
Published in PLoS pathogens (01-02-2014)“…Neutrophils are the host's first line of defense against infections, and their extracellular traps (NET) were recently shown to kill Leishmania parasites. Here…”
Get full text
Journal Article -
15
A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation
Published in Blood (13-01-2011)“…Platelet aggregation and acute inflammation are key processes in vertebrate defense to a skin injury. Recent studies uncovered the mediation of 2 serine…”
Get full text
Journal Article -
16
A Deeper Insight into the Tick Salivary Protein Families under the Light of Alphafold2 and Dali: Introducing the TickSialoFam 2.0 Database
Published in International journal of molecular sciences (09-12-2022)“…Hard ticks feed for several days or weeks on their hosts and their saliva contains thousands of polypeptides belonging to dozens of families, as identified by…”
Get full text
Journal Article -
17
Genomics of Loa loa, a Wolbachia-free filarial parasite of humans
Published in Nature genetics (01-05-2013)“…Thomas Nutman and colleagues report the draft genome of the filarial pathogen Loa loa , the African eyeworm. They also report coverage of two other filarial…”
Get full text
Journal Article -
18
Identification and Mechanistic Analysis of a Novel Tick-Derived Inhibitor of Thrombin
Published in PloS one (05-08-2015)“…A group of peptides from the salivary gland of the tick Hyalomma marginatum rufipes, a vector of Crimean Congo hemorrhagic fever show weak similarity to the…”
Get full text
Journal Article -
19
Towards a semen proteome of the dengue vector mosquito: protein identification and potential functions
Published in PLoS neglected tropical diseases (15-03-2011)“…No commercially licensed vaccine or treatment is available for dengue fever, a potentially lethal infection that impacts millions of lives annually. New tools…”
Get full text
Journal Article -
20
Stage-specific proteomic expression patterns of the human filarial parasite Brugia malayi and its endosymbiont Wolbachia
Published in Proceedings of the National Academy of Sciences - PNAS (07-06-2011)“…Global proteomic analyses of pathogens have thus far been limited to unicellular organisms (e.g., protozoa and bacteria). Proteomic analyses of most eukaryotic…”
Get full text
Journal Article