Lymphocyte Levels and Morbidity and Mortality in Cardiovascular Surgery With Cardiopulmonary Bypass

Lymphocyte Levels and Morbidity and Mortality in Cardiovascular Surgery With Cardiopulmonary Bypass

A year ago, in a sample of 113 patients, our research group found that a high number of lymphocytes in the immediate postoperative period was correlated to a poor prognosis in cardiovascular surgeries. This study is an expansion of the initial study in order to confirm this finding. We analyzed the...

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Bibliographic Details
Published in:Revista brasileira de cirurgia cardiovascular Vol. 39; no. 4; p. e20230136
Main Authors: Castro, Renata Costa Café de, Costa, Paula Natividade, Rocha, Eduardo Augusto Victor, Ribeiro, Isabella Victoria da Cunha Peixoto, Parreira, Maria Paula
Format: Journal Article
Language:English
Published: Brazil Sociedade Brasileira de Cirurgia Cardiovascular 01-01-2024
Subjects:
Adult
Aged
CARDIAC & CARDIOVASCULAR SYSTEMS
Cardiopulmonary Bypass - adverse effects
Cardiopulmonary Bypass - mortality
Cardiovascular Surgical Procedures - mortality
Female
Humans
Intensive Care Units - statistics & numerical data
Length of Stay
Lymphocyte Count
Lymphocytes
Male
Middle Aged
Postoperative Complications - mortality
Postoperative Period
Prognosis
Retrospective Studies
Risk Factors
SURGERY
Lymphocyte Count
Cardiovascular Surgical Procedures
Indicators of Morbidity and Mortality
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Summary:A year ago, in a sample of 113 patients, our research group found that a high number of lymphocytes in the immediate postoperative period was correlated to a poor prognosis in cardiovascular surgeries. This study is an expansion of the initial study in order to confirm this finding. We analyzed the data of 338 consecutive patients submitted to cardiovascular surgeries with cardiopulmonary bypass performed at Hospital Universitário Ciências Médicas (Belo Horizonte/Brazil) from 2015 to 2017. We analyzed 39 variables with the outcomes death, hospital stay, and intensive care unit stay. The value of lymphocytes in the immediate postoperative period > 2175.0/mm³ was an indicator of poor prognosis in this sample (P<0.001). The variables female sex, age, high level of European System for Cardiac Operative Risk Evaluation II, increased stay in the intensive care unit and in the ward, elevation of creatinine in the preoperative period and at intensive care unit discharge, elevation of the percentage of immediate postoperative period segmented neutrophils, high immediate postoperative period neutrophil/lymphocyte ratio, fasting hyperglycemia, preoperative critical condition, reintubation, mild or transient acute renal failure, surgical infection, cardiopulmonary bypass, and aortic cross-clamping and mechanical ventilation durations also had an impact on the mortality outcome. The value of lymphocytes in the immediate postoperative period > 2175.0/mm3 was an indicator of poor prognosis in cardiovascular surgery with cardiopulmonary bypass.
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ISSN:1678-9741
1678-9741
DOI:10.21470/1678-9741-2023-0136