Search Results - "Ribeiro, Frederico F"
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Docking Studies for Multi-Target Drugs
Published in Current drug targets (01-04-2017)“…The most basic principle of drug action is found in the lock and key model, where the highest possible affinity for a target that also avoids side effects is…”
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Multi-Target Drugs for Neglected Diseases
Published in Current pharmaceutical design (30-05-2016)“…Diseases perceived as neglected tropical infections are generally caused by parasites which reach poor, underserved populations (primarily infrastructure),…”
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Pharmacophore Modeling, Synthesis, Scaffold Hopping and Biological β- Hematin Inhibition Interaction Studies for Anti-malaria Compounds
Published in Current topics in medicinal chemistry (01-01-2019)“…Backgound: Exploring potent compounds is critical to generating multi-target drug discovery. Hematin crystallization is an important mechanism of malaria. A…”
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4
Docking of Natural Products against Neurodegenerative Diseases: General Concepts
Published in Combinatorial chemistry & high throughput screening (01-01-2018)“…Since antiquity, humanity has used medicinal plant preparations to cure its ills, and, as research has progressed, new technologies have enabled more…”
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In silico and In vivo Toxicological Evaluation of Cissampelos Sympodialis Secondary Metabolites in Rattus Norvegicus
Published in Current drug metabolism (01-06-2017)“…Cissampelos sympodialis is a plant in northeastern Brazil used by the populace for treating respiratory diseases. Several studies have shown that ethanol leaf…”
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In vitro anti-Leishmania activity and molecular docking of spiro-acridine compounds as potential multitarget agents against Leishmania infantum
Published in Bioorganic & medicinal chemistry letters (01-10-2021)“…[Display omitted] Leishmaniasis is an infectious disease with several limitations regarding treatment schemes. This work reports the anti-Leishmania activity…”
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Antileishmanial activity of new thiophene–indole hybrids: Design, synthesis, biological and cytotoxic evaluation, and chemometric studies
Published in Bioorganic & medicinal chemistry (15-09-2016)“…[Display omitted] •32 hybrid thiophene–indolyl derivatives were synthesized and characterized.•Various compounds showed good antileishmanial activity (IC50…”
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Computational and Investigative Study of Flavonoids Active Against Typanosoma cruzi and Leishmania spp
Published in Natural product communications (01-06-2015)“…Flavonoid compounds active against Trypanosoma cruzi and Leishmania species were submitted to several methodologies in silico: docking with the enzymes cruzain…”
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Antithyroglobulin antibodies in patients with differentiated thyroid carcinoma: methods of detection, interference with serum thyroglobulin measurement and clinical significance
Published in Arquivos brasileiros de endocrinologia e metabologia (01-08-2004)“…Antithyroglobulin antibodies (TgAb) were measured using a chemiluminescent immunoassay (ICMA) and an agglutination test. TgAb laboratory and clinical…”
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5 mCi pretreatment scanning does not cause stunning when the ablative dose is administered within 72 hours
Published in Arquivos brasileiros de endocrinologia e metabologia (01-06-2005)“…To determine the stunning effect of a tracer dose of 5 mCi iodine-131. We retrospectively analyzed 145 patients who received the first ablative treatment at…”
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Usefulness of radioiodine scanning in patients with moderate/high risk differentiated thyroid carcinoma in whom thyroglobulin after thyroxin withdrawal is undetectable after initial treatment
Published in Arquivos brasileiros de endocrinologia e metabologia (01-06-2004)“…We selected 92 patients without antithyroglobulin antibodies (TgAb), in whom thyroglobulin (Tg) after L-thyroxin withdrawal was undetectable (<1 ng/ml) 6-12…”
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Valor da varredura com radioiodo em pacientes com carcinoma diferenciado de tireóide de moderado / alto risco com tireoglobulina (sem tiroxina) indetectável após o tratamento inicial
Published in Arquivos brasileiros de endocrinologia e metabologia (01-06-2004)“…Avaliamos 92 pacientes sem anticorpos anti-tireoglobulina (TgAb) com nível de tireoglobulina (Tg) após suspensão de levotiroxina, indetectável (<1ng/ml) 6 a 12…”
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13
5mCi pretreatment scanning does not cause stunning when the ablative dose is administered within 72 hours
Published in Arquivos brasileiros de endocrinologia e metabologia (01-06-2005)“…OBJECTIVE: To determine the stunning effect of a tracer dose of 5mCi iodine-131. PATIENTS AND METHODS: We retrospectively analyzed 145 patients who received…”
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14
Valor da varredura com radioiodo em pacientes com carcinoma diferenciado de tireóide de moderado / alto risco com tireoglobulina (sem tiroxina) indetectável após o tratamento inicial
Published in Arquivos brasileiros de endocrinologia e metabologia (01-06-2004)“…Avaliamos 92 pacientes sem anticorpos anti-tireoglobulina (TgAb) com nível de tireoglobulina (Tg) após suspensão de levotiroxina, indetectável (<1ng/ml) 6 a 12…”
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