Search Results - "Ribeiro, Fabíola Mara"
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Antidepressant-like effect of valproic acid—Possible involvement of PI3K/Akt/mTOR pathway
Published in Behavioural brain research (30-06-2017)“…•VPA revealed antidepressant-like effect in FS and TS tests in mice.•VPA increased hippocampal phospho-Akt levels in WT, but not in PI3Kγ−/− mice.•The…”
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Ion Channels-related Neuroprotection and Analgesia Mediated by Spider Venom Peptides
Published in Current protein & peptide science (01-01-2023)“…Ion channels play critical roles in generating and propagating action potentials and in neurotransmitter release at a subset of excitatory and inhibitory…”
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Chronic hyperpalatable diet induces impairment of hippocampal-dependent memories and alters glutamatergic and fractalkine axis signaling
Published in Scientific reports (29-09-2023)“…Chronic consumption of hyperpalatable and hypercaloric foods has been pointed out as a factor associated with cognitive decline and memory impairment in…”
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NVP-BEZ235 (Dactolisib) Has Protective Effects in a Transgenic Mouse Model of Alzheimer’s Disease
Published in Frontiers in pharmacology (13-11-2019)“…Alzheimer’s disease (AD) is a neurodegenerative disease and the main cause of dementia. Its major symptom is memory loss, which is a result of neuronal cell…”
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Animal models of neurodegenerative diseases
Published in Revista brasileira de psiquiatria (2013)“…The prevalence of neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD), increases with age, and the number of affected…”
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Isradipine, an L-type calcium channel blocker, attenuates cocaine effects in mice by reducing central glutamate release
Published in European journal of pharmacology (15-05-2024)“…Substance abuse disorder is a chronic condition for which pharmacological treatment options remain limited. L-type calcium channels (LTCC) have been implicated…”
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Murine model to study brain,behavior and immunity during hepatic encephalopathy
Published in World journal of hepatology (27-04-2014)“…AIM:To propose an alternative model of hepatic encephalopathy(HE) in mice,resembling the human features of the disease.METHODS:Mice received two consecutive…”
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Cannabidiol anticonvulsant effect is mediated by the PI3Kγ pathway
Published in Neuropharmacology (01-10-2020)“…The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB/Akt)/mechanistic target of rapamycin (mTOR) signaling pathway has been associated with several…”
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Sex and the Estrous-Cycle Phase Influence the Expression of G Protein-Coupled Estrogen Receptor 1 (GPER) in Schizophrenia: Translational Evidence for a New Target
Published in Molecular neurobiology (01-07-2023)“…Schizophrenia is a mental disorder with sex bias in disease onset and symptom severity. Recently, it was observed that females present more severe symptoms in…”
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Implications of VIP and PACAP in Parkinson's Disease: What do we Know So Far?
Published in Current medicinal chemistry (01-01-2021)“…Parkinson's disease is one of the most common neurodegenerative disorders and although its aetiology is not yet fully understood, neuroinflammation has been…”
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Consumption of Diet Containing Free Amino Acids Exacerbates Colitis in Mice
Published in Frontiers in immunology (20-11-2017)“…Dietary proteins can influence the maturation of the immune system, particularly the gut-associated lymphoid tissue, when consumed from weaning to adulthood…”
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Phoneutria toxin PnTx3-5 inhibits TRPV1 channel with antinociceptive action in an orofacial pain model
Published in Neuropharmacology (01-01-2020)“…Capsaicin, an agonist of TRPV1, evokes intracellular [Ca2+] transients and glutamate release from perfused trigeminal ganglion. The spider toxin PnTx3-5,…”
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Neuroprotective effects of the anticancer drug NVP-BEZ235 (dactolisib) on amyloid-β 1–42 induced neurotoxicity and memory impairment
Published in Scientific reports (04-05-2016)“…Alzheimer’s Disease (AD) is a progressive neurodegenerative disease and the main cause of dementia. Substantial evidences indicate that there is…”
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Gut microbiota from patients with COVID-19 cause alterations in mice that resemble post-COVID symptoms
Published in Gut microbes (18-12-2023)“…Long-term sequelae of coronavirus disease (COVID)-19 are frequent and of major concern. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection…”
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Molecular mechanisms underlying the neuroprotection of environmental enrichment in Parkinson's disease
Published in Neural regeneration research (01-07-2023)“…Parkinson's disease is the most common movement disorder, affecting about 1% of the population over the age of 60 years. Parkinson's disease is characterized…”
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7-Deaza-7-fluoro-2′-C-methyladenosine inhibits Zika virus infection and viral-induced neuroinflammation
Published in Antiviral research (01-08-2020)“…Zika virus (ZIKV) has gained a lot of attention in the past few years due to its rapid spread worldwide and its close association to severe neurological…”
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Muscle atrophy is associated with cervical spinal motoneuron loss in BACHD mouse model for Huntington's disease
Published in The European journal of neuroscience (01-03-2017)“…Involuntary choreiform movements are clinical hallmark of Huntington's disease, an autosomal dominant neurodegenerative disorder caused by an increased number…”
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A Neuroprotective Effect of the Glutamate Receptor Antagonist MK801 on Long-Term Cognitive and Behavioral Outcomes Secondary to Experimental Cerebral Malaria
Published in Molecular neurobiology (01-11-2017)“…Cerebral malaria (CM) is a life-threatening complication of Plasmodium falciparum infection, which can result in long-term cognitive and behavioral deficits…”
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T-lymphocytes response persists following Plasmodium berghei strain Anka infection resolution and may contribute to later experimental cerebral malaria outcomes
Published in Journal of neuroimmunology (15-05-2019)“…Several studies have proposed cerebral malaria (CM) as a CD4+ and CD8+ T lymphocyte-mediated disease. However, there are no data regarding the recruitment…”
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Changes in structure and function of diaphragm neuromuscular junctions from BACHD mouse model for Huntington's disease
Published in Neurochemistry international (01-02-2016)“…Huntington's disease (HD) is a neurodegenerative disorder characterized by a progressive decline of motor and cognitive functions. It is caused by a…”
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