Search Results - "Ribeck, Noah"
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Long-Term Dynamics of Adaptation in Asexual Populations
Published in Science (American Association for the Advancement of Science) (13-12-2013)“…Experimental studies of evolution have increased greatly in number in recent years, stimulated by the growing power of genomic tools. However, organismal…”
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DNA unwinding by ring-shaped T4 helicase gp41 is hindered by tension on the occluded strand
Published in PloS one (08-11-2013)“…The replicative helicase for bacteriophage T4 is gp41, which is a ring-shaped hexameric motor protein that achieves unwinding of dsDNA by translocating along…”
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Tempo and mode of genome evolution in a 50,000-generation experiment
Published in Nature (London) (11-08-2016)“…Adaptation by natural selection depends on the rates, effects and interactions of many mutations, making it difficult to determine what proportion of mutations…”
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Modeling and quantifying frequency-dependent fitness in microbial populations with cross-feeding interactions
Published in Evolution (01-05-2015)“…Coexistence of two or more populations by frequency-dependent selection is common in nature, and it often arises even in well-mixed experiments with microbes…”
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Multiplexed single-molecule measurements with magnetic tweezers
Published in Review of scientific instruments (01-09-2008)“…We present a method for performing multiple single-molecule manipulation experiments in parallel with magnetic tweezers. We use a microscope with a low…”
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Modeling and quantifying frequency-dependent fitness in microbial populations with cross-feeding interactions: BRIEF COMMUNICATION
Published in Evolution (01-05-2015)Get full text
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Sustained fitness gains and variability in fitness trajectories in the long-term evolution experiment with Escherichia coli
Published in Proceedings of the Royal Society. B, Biological sciences (22-12-2015)“…Many populations live in environments subject to frequent biotic and abiotic changes. Nonetheless, it is interesting to ask whether an evolving population's…”
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DnaB Helicase Activity Is Modulated by DNA Geometry and Force
Published in Biophysical journal (06-10-2010)“…The replicative helicase for Escherichia coli is DnaB, a hexameric, ring-shaped motor protein that encircles and translocates along ssDNA, unwinding dsDNA in…”
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DNA Unwinding By DnaB and the DnaB/TAU Complex
Published in Biophysical journal (01-01-2010)Get full text
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Investigating Hexameric Helicases: Single-Molecule Studies of DnaB and T4 Gp41
Published in Biophysical journal (01-02-2011)Get full text
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Single-molecule Measurements Of DnaB
Published in Biophysical journal (01-02-2009)Get full text
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Single-molecule and bulk approaches to the DnaB replication fork helicase
Published in Frontiers in bioscience (01-01-2013)“…Motor proteins are enzymes that accomplish mechanical work in a wide variety of biological processes. In this review we focus on bulk and single molecule…”
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Sustained fitness gains and variability in fitness trajectories in the long-term evolution experiment with Escherichia coli
Published in Proceedings of the Royal Society. B, Biological sciences (22-12-2015)“…Many populations live in environments subject to frequent biotic and abiotic changes. Nonetheless, it is interesting to ask whether an evolving population's…”
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Journal Article -
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Non-ideal Elasticity Of Single Stranded DNA At Low Forces
Published in Biophysical journal (01-02-2009)Get full text
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Single-Molecule Measurements of the Helicase DnaB with Magnetic Tweezers
Published 01-01-2011“…We present a multifaceted single-molecule strategy for quantifying the physical interactions between the helicase DnaB and the DNA at a replication fork. To…”
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Dissertation -
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Single-Molecule Measurements of the Helicase DnaB with Magnetic Tweezers
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Dissertation