Search Results - "Rhyne, Paul W."
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Pharmacodynamics of selective inhibition of γ-secretase by avagacestat
Published in The Journal of pharmacology and experimental therapeutics (01-03-2013)“…A hallmark of Alzheimer's disease (AD) pathology is the accumulation of brain amyloid β-peptide (Aβ), generated by γ-secretase-mediated cleavage of the amyloid…”
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Pharmacokinetic equivalence, comparable safety, and immunogenicity of an adalimumab biosimilar product (M923) to Humira in healthy subjects
Published in Pharmacology research & perspectives (01-02-2018)“…The aims of this randomized, double‐blind, three‐arm, single‐dose study were to demonstrate pharmacokinetic (PK) equivalence of the adalimumab biosimilar M923…”
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Analysis of apoptotic cells using Beadlyte suspension arrays
Published in BioTechniques (01-09-2003)“…Here we describe a new approach to study apoptosis pathways using multiplex suspension arrays. Apoptosis was induced in Jurkat T cells using the protein…”
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Electrochemiluminescence in bioanalysis
Published in Bioanalysis (01-08-2009)“…The discovery of electrochemiluminescence (ECL) and its development as a means of detection is truly a success story. Although studies describing ECL were…”
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Immunoassay-based measurement of clinical biomarkers for monitoring changes in nasal cavity
Published in Journal of pharmaceutical and biomedical analysis (05-12-2009)“…Many drugs for treatment of allergies, migraine headaches, inflammation, and other indications are administered into the nasal cavity providing access to the…”
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Epstein-Barr Virus Small RNAs Potentiate Tumorigenicity of Burkitt Lymphoma Cells Independently of an Effect on Apoptosis
Published in Journal of Virology (01-11-2000)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Characterization and development of a Luminex(®)-based assay for the detection of human IL-23
Published in Bioanalysis (01-09-2010)“…IL-23 is a cytokine produced by dendritic cells, T-cells and macrophages that plays a critical regulatory role in the inflammatory and autoimmune responses. We…”
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Epstein-Barr Virus Regulates c-MYC, Apoptosis, and Tumorigenicity in Burkitt Lymphoma
Published in Molecular and Cellular Biology (01-03-1999)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Isolation of Antibody to Human Placental Alkaline Phosphatase (PLAP) from Extracts of Human Placentae
Published in American journal of reproductive immunology (1989) (01-08-2001)“…PROBLEM: Human placental alkaline phosphatase (PLAP) is a unique placental antigen bound to the syncytiotrophoblast, which may be able to elicit a specific…”
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