Search Results - "Rhun Yian Koh"
-
1
Roles of receptor‐interacting protein kinase 1 in SH‐SY5Y cells with beta amyloid‐induced neurotoxicity
Published in Journal of cellular and molecular medicine (01-03-2022)“…Alzheimer's disease (AD), the major cause of dementia, affects the elderly population worldwide. Previous studies have shown that depletion of…”
Get full text
Journal Article -
2
Association among Lifestyle and Risk Factors with SARS-CoV-2 Infection
Published in Tuberculosis and respiratory diseases (01-04-2023)“…Coronavirus disease 2019 (COVID-19) has become a major health burden worldwide, with over 600 million confirmed cases and 6 million deaths by 15 December 2022…”
Get full text
Journal Article -
3
Association among Lifestyle and Risk Factors with SARS-CoV-2 Infection
Published in Tuberculosis and respiratory diseases (2023)“…Coronavirus disease 2019 (COVID-19) has become a major health burden worldwide, with over 600 million confirmed cases and 6 million deaths by 15 December 2022…”
Get full text
Journal Article -
4
Mechanisms of action of amyloid-beta and its precursor protein in neuronal cell death
Published in Metabolic brain disease (2020)“…Extracellular senile plaques and intracellular neurofibrillary tangles are the neuropathological findings of the Alzheimer’s disease (AD). Based on the amyloid…”
Get full text
Journal Article -
5
Melatonin Induces Autophagy via Reactive Oxygen Species-Mediated Endoplasmic Reticulum Stress Pathway in Colorectal Cancer Cells
Published in Molecules (Basel, Switzerland) (20-08-2021)“…Even though an increasing number of anticancer treatments have been discovered, the mortality rates of colorectal cancer (CRC) have still been high in the past…”
Get full text
Journal Article -
6
Pharmacological Effects of Melatonin as Neuroprotectant in Rodent Model: A Review on the Current Biological Evidence
Published in Cellular and molecular neurobiology (01-01-2020)“…The progressive loss of structure and functions of neurons, including neuronal death, is one of the main factors leading to poor quality of life. Promotion of…”
Get full text
Journal Article -
7
How Do Abnormalities in the Cerebrospinal Fluid Impact Neuropsychology with Progressing Age?
Published in CNS & neurological disorders drug targets (01-01-2023)“…The behavior of an individual changes from neonate to elderly due to the development of the central nervous system (CNS). One of the important components of…”
Get more information
Journal Article -
8
Prevention of Parkinson's Disease: From Risk Factors to Early Interventions
Published in CNS & neurological disorders drug targets (01-01-2024)“…Parkinson's disease (PD) is a debilitating neurological disorder characterized by progressively worsening motor dysfunction. Currently, available therapies…”
Get more information
Journal Article -
9
Edible Bird’s Nest: Recent Updates and Industry Insights Based On Laboratory Findings
Published in Frontiers in pharmacology (01-10-2021)“…Edible bird’s nest (EBN) is a traditional Chinese delicacy made of the saliva of swiftlets found in Southeast Asia. With increasing demands for EBN, quality…”
Get full text
Journal Article -
10
Endosomal‐lysosomal dysfunctions in Alzheimer’s disease: Pathogenesis and therapeutic interventions
Published in Metabolic brain disease (01-08-2021)“…The endosomal-lysosomal system mediates the process of protein degradation through endocytic pathway. This system consists of early endosomes, late endosomes,…”
Get full text
Journal Article -
11
Recent advances in tau-directed immunotherapy against Alzheimer’s disease: an overview of pre-clinical and clinical development
Published in Metabolic brain disease (01-10-2020)“…Alzheimer’s disease (AD) has been a worldwide concern for many years now. This is due to the fact that AD is an irreversible and progressive neurodegenerative…”
Get full text
Journal Article -
12
The Role of Monoamine Oxidase B Inhibitors in the Treatment of Parkinson's Disease - An Update
Published in CNS & neurological disorders drug targets (01-01-2023)“…Parkinson's disease (PD) is a progressive neurodegenerative disease characterised by reduced dopamine levels in the substantial nigra. This may lead to typical…”
Get more information
Journal Article -
13
A Review on Medicinal Properties of Orientin
Published in Advances in Pharmacological Sciences (01-01-2016)“…Medicinal plants continue to play an important role in modern medications and healthcare as consumers generally believe that most of them cause fewer or milder…”
Get full text
Journal Article -
14
Biomedical science students’ perception of the use of role-play in learning stress and anger management skills
Published in Asia Pacific Scholar (Online) (01-04-2024)“…Introduction: People skills play a crucial role in the professional development of Biomedical Scientists. A laboratory management and professional practice…”
Get full text
Journal Article -
15
Melatonin Prevents Oxidative Stress-Induced Mitochondrial Dysfunction and Apoptosis in High Glucose-Treated Schwann Cells via Upregulation of Bcl2, NF-κB, mTOR, Wnt Signalling Pathways
Published in Antioxidants (26-06-2019)“…Neuropathy is a complication that affects more than 50% of long-standing diabetic patients. One of the causes of diabetes neuropathy (DN) is the apoptosis of…”
Get full text
Journal Article -
16
Immunotherapies for Parkinson's Disease: Progression of Clinical Development
Published in CNS & neurological disorders drug targets (2021)“…Parkinson's disease is a common neurodegenerative disease affecting the movement and well-being of most elderly. The manifestations of Parkinson's disease…”
Get more information
Journal Article -
17
Physicochemical and antimicrobial properties of natural rubber latex films in the presence of vegetable oil microemulsions
Published in Journal of applied polymer science (10-05-2017)“…ABSTRACT A series of vegetable oil microemulsions are formulated and incorporated into NR latex to study the potent antimicrobial activity of vegetable…”
Get full text
Journal Article -
18
Edible bird’s nest improves motor behavior and protects dopaminergic neuron against oxidative and nitrosative stress in Parkinson’s disease mouse model
Published in Journal of functional foods (01-09-2018)“…[Display omitted] •Sub-chronic treatment of EBN has no observable toxic effect on mice.•EBN improves motor function, locomotor activity and balancing in PD…”
Get full text
Journal Article -
19
Neuroprotective effects of orientin on hydrogen peroxide-induced apoptosis in SH-SY5Y cells
Published in Molecular medicine reports (01-03-2014)“…Neurodegenerative diseases remain a global issue which affects the ageing population. Efforts towards determining their aetiologies to understand their…”
Get full text
Journal Article -
20
Development and Evaluation of Curcumin Liquid Crystal Systems for Cervical Cancer
Published in Scientia pharmaceutica (01-03-2020)“…Curcumin is a hydrophobic compound with good anti-proliferative, anti-oxidative, and anti-cancer properties but has poor bioavailability. Liquid crystals (LC)…”
Get full text
Journal Article