Search Results - "Rhun Yian Koh"

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  1. 1

    Roles of receptor‐interacting protein kinase 1 in SH‐SY5Y cells with beta amyloid‐induced neurotoxicity by Chan, Hong‐Hao, Leong, Chee‐Onn, Lim, Chooi‐Ling, Koh, RhunYian

    Published in Journal of cellular and molecular medicine (01-03-2022)
    “…Alzheimer's disease (AD), the major cause of dementia, affects the elderly population worldwide. Previous studies have shown that depletion of…”
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  2. 2

    Association among Lifestyle and Risk Factors with SARS-CoV-2 Infection by Ko, Yi, Ngai, Zi-Ni, Koh, Rhun-Yian, Chye, Soi-Moi

    Published in Tuberculosis and respiratory diseases (01-04-2023)
    “…Coronavirus disease 2019 (COVID-19) has become a major health burden worldwide, with over 600 million confirmed cases and 6 million deaths by 15 December 2022…”
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  3. 3

    Association among Lifestyle and Risk Factors with SARS-CoV-2 Infection by Yi Ko, Zi-ni Ngai, Rhun-yian Koh, Soi-moi Chye

    “…Coronavirus disease 2019 (COVID-19) has become a major health burden worldwide, with over 600 million confirmed cases and 6 million deaths by 15 December 2022…”
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  4. 4

    Mechanisms of action of amyloid-beta and its precursor protein in neuronal cell death by Leong, Yong Qi, Ng, Khuen Yen, Chye, Soi Moi, Ling, Anna Pick Kiong, Koh, Rhun Yian

    Published in Metabolic brain disease (2020)
    “…Extracellular senile plaques and intracellular neurofibrillary tangles are the neuropathological findings of the Alzheimer’s disease (AD). Based on the amyloid…”
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  5. 5

    Melatonin Induces Autophagy via Reactive Oxygen Species-Mediated Endoplasmic Reticulum Stress Pathway in Colorectal Cancer Cells by Chok, Kian Chung, Koh, Rhun Yian, Ng, Ming Guan, Ng, Pei Ying, Chye, Soi Moi

    Published in Molecules (Basel, Switzerland) (20-08-2021)
    “…Even though an increasing number of anticancer treatments have been discovered, the mortality rates of colorectal cancer (CRC) have still been high in the past…”
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  6. 6

    Pharmacological Effects of Melatonin as Neuroprotectant in Rodent Model: A Review on the Current Biological Evidence by Tan, Hui Ying, Ng, Khuen Yen, Koh, Rhun Yian, Chye, Soi Moi

    Published in Cellular and molecular neurobiology (01-01-2020)
    “…The progressive loss of structure and functions of neurons, including neuronal death, is one of the main factors leading to poor quality of life. Promotion of…”
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  7. 7

    How Do Abnormalities in the Cerebrospinal Fluid Impact Neuropsychology with Progressing Age? by Joshi, Gargi, Ling, Anna Pick Kiong, Chye, Soi Moi, Koh, Rhun Yian

    Published in CNS & neurological disorders drug targets (01-01-2023)
    “…The behavior of an individual changes from neonate to elderly due to the development of the central nervous system (CNS). One of the important components of…”
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  8. 8

    Prevention of Parkinson's Disease: From Risk Factors to Early Interventions by Ng, Ming Guan, Chan, Brendan Jun Lam, Koh, Rhun Yian, Ng, Khuen Yen, Chye, Soi Moi

    Published in CNS & neurological disorders drug targets (01-01-2024)
    “…Parkinson's disease (PD) is a debilitating neurological disorder characterized by progressively worsening motor dysfunction. Currently, available therapies…”
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  9. 9

    Edible Bird’s Nest: Recent Updates and Industry Insights Based On Laboratory Findings by Chok, Kian Chung, Ng, Ming Guan, Ng, Khuen Yen, Koh, Rhun Yian, Tiong, Yee Lian, Chye, Soi Moi

    Published in Frontiers in pharmacology (01-10-2021)
    “…Edible bird’s nest (EBN) is a traditional Chinese delicacy made of the saliva of swiftlets found in Southeast Asia. With increasing demands for EBN, quality…”
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  10. 10

    Endosomal‐lysosomal dysfunctions in Alzheimer’s disease: Pathogenesis and therapeutic interventions by Lai, Shereen Shi Min, Ng, Khuen Yen, Koh, Rhun Yian, Chok, Kian Chung, Chye, Soi Moi

    Published in Metabolic brain disease (01-08-2021)
    “…The endosomal-lysosomal system mediates the process of protein degradation through endocytic pathway. This system consists of early endosomes, late endosomes,…”
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  11. 11

    Recent advances in tau-directed immunotherapy against Alzheimer’s disease: an overview of pre-clinical and clinical development by Ng, Pei Ying, Chang, I Shuen, Koh, Rhun Yian, Chye, Soi Moi

    Published in Metabolic brain disease (01-10-2020)
    “…Alzheimer’s disease (AD) has been a worldwide concern for many years now. This is due to the fact that AD is an irreversible and progressive neurodegenerative…”
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  12. 12

    The Role of Monoamine Oxidase B Inhibitors in the Treatment of Parkinson's Disease - An Update by Chew, Zhi Xin, Lim, Chooi Ling, Ng, Khuen Yen, Chye, Soi Moi, Ling, Anna Pick Kiong, Koh, Rhun Yian

    Published in CNS & neurological disorders drug targets (01-01-2023)
    “…Parkinson's disease (PD) is a progressive neurodegenerative disease characterised by reduced dopamine levels in the substantial nigra. This may lead to typical…”
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  13. 13

    A Review on Medicinal Properties of Orientin by Lam, Kit Ying, Ling, Anna Pick Kiong, Koh, Rhun Yian, Wong, Ying Pei, Say, Yee How

    Published in Advances in Pharmacological Sciences (01-01-2016)
    “…Medicinal plants continue to play an important role in modern medications and healthcare as consumers generally believe that most of them cause fewer or milder…”
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  14. 14

    Biomedical science students’ perception of the use of role-play in learning stress and anger management skills by Chye, Soi Moi, Koh, Rhun Yian, Shankar, Pathiyil Ravi

    Published in Asia Pacific Scholar (Online) (01-04-2024)
    “…Introduction: People skills play a crucial role in the professional development of Biomedical Scientists. A laboratory management and professional practice…”
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  15. 15

    Melatonin Prevents Oxidative Stress-Induced Mitochondrial Dysfunction and Apoptosis in High Glucose-Treated Schwann Cells via Upregulation of Bcl2, NF-κB, mTOR, Wnt Signalling Pathways by Tiong, Yee Lian, Ng, Khuen Yen, Koh, Rhun Yian, Ponnudurai, Gnanajothy, Chye, Soi Moi

    Published in Antioxidants (26-06-2019)
    “…Neuropathy is a complication that affects more than 50% of long-standing diabetic patients. One of the causes of diabetes neuropathy (DN) is the apoptosis of…”
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  16. 16

    Immunotherapies for Parkinson's Disease: Progression of Clinical Development by Teng, Jet Shee, Ooi, Yin Yin, Chye, Soi Moi, Ling, Anna Pick Kiong, Koh, Rhun Yian

    “…Parkinson's disease is a common neurodegenerative disease affecting the movement and well-being of most elderly. The manifestations of Parkinson's disease…”
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  17. 17

    Physicochemical and antimicrobial properties of natural rubber latex films in the presence of vegetable oil microemulsions by Lee, Siang Yin, Ng, Angie, Jaswan Singh, Manroshan Singh, Liew, Yun Khoon, Gan, Seng Neon, Koh, Rhun Yian

    Published in Journal of applied polymer science (10-05-2017)
    “…ABSTRACT A series of vegetable oil microemulsions are formulated and incorporated into NR latex to study the potent antimicrobial activity of vegetable…”
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  18. 18

    Edible bird’s nest improves motor behavior and protects dopaminergic neuron against oxidative and nitrosative stress in Parkinson’s disease mouse model by Yew, Mei Yeng, Koh, Rhun Yian, Chye, Soi Moi, Othman, Iekhsan, Soga, Tomoko, Parhar, Ishwar, Ng, Khuen Yen

    Published in Journal of functional foods (01-09-2018)
    “…[Display omitted] •Sub-chronic treatment of EBN has no observable toxic effect on mice.•EBN improves motor function, locomotor activity and balancing in PD…”
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  19. 19

    Neuroprotective effects of orientin on hydrogen peroxide-induced apoptosis in SH-SY5Y cells by LAW, BENJAMIN NGEE TIING, LING, ANNA PICK KIONG, KOH, RHUN YIAN, CHYE, SOI MOI, WONG, YING PEI

    Published in Molecular medicine reports (01-03-2014)
    “…Neurodegenerative diseases remain a global issue which affects the ageing population. Efforts towards determining their aetiologies to understand their…”
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  20. 20

    Development and Evaluation of Curcumin Liquid Crystal Systems for Cervical Cancer by R David, Sheba, Akmar Binti Anwar, Nurul, Yian, Koh Rhun, Mai, Chun-Wai, Das, Sanjoy Kumar, Rajabalaya, Rajan

    Published in Scientia pharmaceutica (01-03-2020)
    “…Curcumin is a hydrophobic compound with good anti-proliferative, anti-oxidative, and anti-cancer properties but has poor bioavailability. Liquid crystals (LC)…”
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