Search Results - "Rhodes, Lyndsay V"

Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers by Strong, Amy L, Ohlstein, Jason F, Biagas, Brandi A, Rhodes, Lyndsay V, Pei, Dorothy T, Tucker, H Alan, Llamas, Claire, Bowles, Annie C, Dutreil, Maria F, Zhang, Shijia, Gimble, Jeffrey M, Burow, Matthew E, Bunnell, Bruce A

“…The steady increase in the incidence of obesity among adults has been paralleled with higher levels of obesity-associated breast cancer. While recent studies…”
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Endocrine disruptor regulation of microRNA expression in breast carcinoma cells by Tilghman, Syreeta L, Bratton, Melyssa R, Segar, H Chris, Martin, Elizabeth C, Rhodes, Lyndsay V, Li, Meng, McLachlan, John A, Wiese, Thomas E, Nephew, Kenneth P, Burow, Matthew E

“…Several environmental agents termed "endocrine disrupting compounds" or EDCs have been reported to bind and activate the estrogen receptor-α (ER). The EDCs DDT…”
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Cytokine Receptor CXCR4 Mediates Estrogen-Independent Tumorigenesis, Metastasis, and Resistance to Endocrine Therapy in Human Breast Cancer by RHODES, Lyndsay V, SHORT, Sarah P, FONSECA, Juan P, BRATTON, Melyssa R, SEGAR, Chris, TILGHMAN, Syreeta L, SOBOLIK-DELMAIRE, Tammy, HORTON, Linda W, ZAJA-MILATOVIC, Snjezana, COLLINS-BUROW, Bridgette M, WADSWORTH, Scott, BECKMAN, Barbara S, NEEL, Nicole F, WOOD, Charles E, FUQUA, Suzanne A, NEPHEW, Kenneth P, DENT, Paul, WORTHYLAKE, Rebecca A, CURIEL, Tyler J, HUNG, Mien-Chie, RICHMOND, Ann, BUROW, Matthew E, SALVO, Virgilio A, YUN ZHU, ELLIOTT, Steven, YONGKUN WEI, DIHUA YU, MENGHONG SUN, MUIR, Shannon E

“…Estrogen independence and progression to a metastatic phenotype are hallmarks of therapeutic resistance and mortality in breast cancer patients. Metastasis has…”
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Drug resistance profiling of a new triple negative breast cancer patient-derived xenograft model by Matossian, Margarite D, Burks, Hope E, Elliott, Steven, Hoang, Van T, Bowles, Annie C, Sabol, Rachel A, Wahba, Bahia, Anbalagan, Muralidharan, Rowan, Brian, Abazeed, Mohamed E, Bunnell, Bruce A, Moroz, Krzysztof, Miele, Lucio, Rhodes, Lyndsay V, Jones, Steven D, Martin, Elizabeth C, Collins-Burow, Bridgette M, Burow, Matthew E

“…Triple-negative breast cancer (TNBC) represents an aggressive subtype with limited therapeutic options. Experimental preclinical models that recapitulate their…”
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Effects of human mesenchymal stem cells on ER-positive human breast carcinoma cells mediated through ER-SDF-1/CXCR4 crosstalk by Rhodes, Lyndsay V, Antoon, James W, Muir, Shannon E, Elliott, Steven, Beckman, Barbara S, Burow, Matthew E

“…Adult human mesenchymal stem cells (hMSC) have been shown to home to sites of carcinoma and affect biological processes, including tumour growth and…”
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Glyceollin, a novel regulator of mTOR/p70S6 in estrogen receptor positive breast cancer by Bratton, Melyssa R., Martin, Elizabeth C., Elliott, Steven, Rhodes, Lyndsay V., Collins-Burow, Bridgette M., McLachlan, John A., Wiese, Thomas E., Boue, Stephen M., Burow, Matthew E.

“…•Glyceollin suppresses phosphorylation of proteins which crosstalk with ERα.•p70S6 is a novel target of glyceollin in ER+ breast cancer cell line.•The effects…”
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Preferential star strand biogenesis of pre-miR-24-2 targets PKC-alpha and suppresses cell survival in MCF-7 breast cancer cells by Martin, Elizabeth C., Elliott, Steven, Rhodes, Lyndsay V., Antoon, James W., Fewell, Claire, Zhu, Yun, Driver, Jennifer L., Jodari-Karimi, Mona, Taylor, Christopher W., Flemington, Erik K., Beckman, Barbara S., Collins-Burow, Bridgette M., Burow, Matthew E.

“…microRNAs (miRNA) are regulators of cellular pathways and alterations of normal miRNA expression levels have been shown to increase tumorigenesis. miR‐24 has…”
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MEK5/ERK5 signaling suppresses estrogen receptor expression and promotes hormone-independent tumorigenesis by Antoon, James W, Martin, Elizabeth C, Lai, Rongye, Salvo, Virgilo A, Tang, Yan, Nitzchke, Ashley M, Elliott, Steven, Nam, Seung Yoon, Xiong, Wei, Rhodes, Lyndsay V, Collins-Burow, Bridgette, David, Odile, Wang, Guandi, Shan, Bin, Beckman, Barbara S, Nephew, Kenneth P, Burow, Matthew E

“…Endocrine resistance and metastatic progression are primary causes of treatment failure in breast cancer. While mitogen activated protein kinases (MAPKs) are…”
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A new method for stranded whole transcriptome RNA-seq by Miller, David F.B., Yan, Pearlly S., Buechlein, Aaron, Rodriguez, Benjamin A., Yilmaz, Ayse S., Goel, Shokhi, Lin, Hai, Collins-Burow, Bridgette, Rhodes, Lyndsay V., Braun, Chris, Pradeep, Sunila, Rupaimoole, Rajesha, Dalkilic, Mehmet, Sood, Anil K., Burow, Matthew E., Tang, Haixu, Huang, Tim H., Liu, Yunlong, Rusch, Douglas B., Nephew, Kenneth P.

“…This report describes an improved protocol to generate stranded, barcoded RNA-seq libraries to capture the whole transcriptome. By optimizing the use of duplex…”
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Insulin-like growth factor-1 signaling regulates miRNA expression in MCF-7 breast cancer cell line by Martin, Elizabeth C, Bratton, Melyssa R, Zhu, Yun, Rhodes, Lyndsay V, Tilghman, Syreeta L, Collins-Burow, Bridgette M, Burow, Matthew E

“…In breast carcinomas, increased levels of insulin-like growth factor 1 (IGF-1) can act as a mitogen to augment tumorigenesis through the regulation of MAPK and…”
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Effects of SDF-1–CXCR4 signaling on microRNA expression and tumorigenesis in estrogen receptor-alpha (ER-α)-positive breast cancer cells by Rhodes, Lyndsay V., Bratton, Melyssa R., Zhu, Yun, Tilghman, Syreeta L., Muir, Shannon E., Salvo, Virgilio A., Tate, Chandra R., Elliott, Steven, Nephew, Kenneth P., Collins-Burow, Bridgette M., Burow, Matthew E.

“…The majority of breast cancer cases ultimately become unresponsive to endocrine therapies, and this progression of breast cancer from hormone-responsive to…”
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Pharmacological inhibition of sphingosine kinase isoforms alters estrogen receptor signaling in human breast cancer by Antoon, James W, Meacham, William D, Bratton, Melyssa R, Slaughter, Evelyn M, Rhodes, Lyndsay V, Ashe, Hasina B, Wiese, Thomas E, Burow, Matthew E, Beckman, Barbara S

“…Recently, crosstalk between sphingolipid signaling pathways and steroid hormones has been illuminated as a possible therapeutic target. Sphingosine kinase…”
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Phytoalexins, miRNAs and breast cancer: a review of phytochemical-mediated miRNA regulation in breast cancer by Tilghman, Syreeta L, Rhodes, Lyndsay V, Bratton, Melyssa R, Carriere, Patrick, Preyan, Lynez C, Boue, Stephen M, Vasaitis, Tadas Sean, McLachlan, John A, Burow, Matthew E

“…There is growing interest in the diverse signaling pathways that regulate and affect breast tumorigenesis, including the role of phytochemicals and the…”
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Targeting triple-negative breast cancer cells with the histone deacetylase inhibitor panobinostat by Tate, Chandra R, Rhodes, Lyndsay V, Segar, H Chris, Driver, Jennifer L, Pounder, F Nell, Burow, Matthew E, Collins-Burow, Bridgette M

“…Of the more than one million global cases of breast cancer diagnosed each year, approximately fifteen percent are characterized as triple-negative, lacking the…”
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Argonaute 2 Expression Correlates with a Luminal B Breast Cancer Subtype and Induces Estrogen Receptor Alpha Isoform Variation by Conger, Adrienne K, Martin, Elizabeth C, Yan, Thomas J, Rhodes, Lyndsay V, Hoang, Van T, La, Jacqueline, Anbalagan, Muralidharan, Burks, Hope E, Rowan, Brian G, Nephew, Kenneth P, Collins-Burow, Bridgette M, Burow, Matthew E

“…Estrogen receptor alpha (ERα) signaling pathways are frequently disrupted in breast cancer and contribute to disease progression. ERα signaling is multifaceted…”
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Abstract 3318: Exploring the utility of natural and synthetic resveratrol derivatives for bone regrowth following loss due to breast cancer therapies by Robert, Evan, Rhodes, Lyndsay V.

“…Abstract Many of the most widely used therapies for the treatment of breast cancer have been associated with enhanced rate of bone loss, including…”
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Resveratrol analogues surprisingly effective against triple‑negative breast cancer, independent of ERα by Horgan, Xylia J, Tatum, Hannah, Brannan, Emily, Paull, Daniel H, Rhodes, Lyndsay V

“…Resveratrol, a plant‑derived stilbene compound, has exhibited anticancerous properties, including breast cancer. Stilbenes have a molecular structure highly…”
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Human mesenchymal stem cells as mediators of breast carcinoma tumorigenesis and progression by Rhodes, Lyndsay V, Burow, Matthew E

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Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer by Rhodes, Lyndsay V, Martin, Elizabeth C, Segar, H Chris, Miller, David F B, Buechlein, Aaron, Rusch, Douglas B, Nephew, Kenneth P, Burow, Matthew E, Collins-Burow, Bridgette M

“…Epithelial to mesenchymal transition (EMT) involves loss of an epithelial phenotype and activation of a mesenchymal one. Enhanced expression of genes…”
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Suppression of triple-negative breast cancer metastasis by pan-DAC inhibitor panobinostat via inhibition of ZEB family of EMT master regulators by Rhodes, Lyndsay V., Tate, Chandra R., Segar, H. Chris, Burks, Hope E., Phamduy, Theresa B., Hoang, Van, Elliott, Steven, Gilliam, Diari, Pounder, F. Nell, Anbalagan, Muralidharan, Chrisey, Douglas B., Rowan, Brian G., Burow, Matthew E., Collins-Burow, Bridgette M.

“…Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype that lacks effective targeted therapies. The epithelial-to-mesenchymal…”
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