Search Results - "Rhodes, Johanna"
-
1
Genomic surveillance urgently needed to control wheat blast pandemic spreading across continents
Published in PLoS biology (12-04-2023)“…A new study in PLOS Biology highlights the alarming potential of a pandemic clone of wheat blast disease to evolve fungicide-insensitive variants and argues…”
Get full text
Journal Article -
2
Airway microbiome: environmental exposure–respiratory health nexus
Published in Trends in molecular medicine (01-11-2023)“…Toxicants such as smoke, biofuel, and pollutants constantly challenge our respiratory health, but little is known about the pathophysiological processes…”
Get full text
Journal Article -
3
Clinical implications of globally emerging azole resistance in Aspergillus fumigatus
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (05-12-2016)“…Aspergillus fungi are the cause of an array of diseases affecting humans, animals and plants. The triazole antifungal agents itraconazole, voriconazole,…”
Get full text
Journal Article -
4
First hospital outbreak of the globally emerging Candida auris in a European hospital
Published in Antimicrobial resistance & infection control (19-10-2016)“…is a globally emerging multidrug resistant fungal pathogen causing nosocomial transmission. We report an ongoing outbreak of in a London cardio-thoracic center…”
Get full text
Journal Article -
5
Tackling the emerging threat of antifungal resistance to human health
Published in Nature reviews. Microbiology (01-09-2022)“…Invasive fungal infections pose an important threat to public health and are an under-recognized component of antimicrobial resistance, an emerging crisis…”
Get full text
Journal Article -
6
Phenotypic Variants of Azole-Resistant Aspergillus Fumigatus that Co-exist in Human Respiratory Samples are Genetically Highly Related
Published in Mycopathologia (1975) (01-12-2022)“…Respiratory specimens obtained from patients with chronic forms of aspergillosis contain phenotypic variants of azole-resistant Aspergillus fumigatus (ARAF)…”
Get full text
Journal Article -
7
Architecture and Dynamics of the Jasmonic Acid Gene Regulatory Network
Published in The Plant cell (01-09-2017)“…Jasmonic acid (JA) is a critical hormonal regulator of plant growth and defense. To advance our understanding of the architecture and dynamic regulation of the…”
Get full text
Journal Article -
8
Long-read Sequencing and de novo Genome Assembly of Three Aspergillus fumigatus Genomes
Published in Mycopathologia (1975) (01-08-2023)“…Aspergillus fumigatus is a genetically diverse fungal species, which is near ubiquitous in its global distribution and is the major cause of the…”
Get full text
Journal Article -
9
Nonrandom Distribution of Azole Resistance across the Global Population of Aspergillus fumigatus
Published in mBio (21-05-2019)“…The emergence of azole resistance in the pathogenic fungus has continued to increase, with the dominant resistance mechanisms, consisting of a 34-nucleotide…”
Get full text
Journal Article -
10
Genomic Context of Azole Resistance Mutations in Aspergillus fumigatus Determined Using Whole-Genome Sequencing
Published in mBio (02-06-2015)“…A rapid and global emergence of azole resistance has been observed in the pathogenic fungus Aspergillus fumigatus over the past decade. The dominant resistance…”
Get full text
Journal Article -
11
Arabidopsis Defense against Botrytis cinerea: Chronology and Regulation Deciphered by High-Resolution Temporal Transcriptomic Analysis
Published in The Plant cell (01-09-2012)“…Transcriptional reprogramming forms a major part of a plant's response to pathogen infection. Many individual components and pathways operating during plant…”
Get full text
Journal Article -
12
The one health problem of azole resistance in Aspergillus fumigatus: current insights and future research agenda
Published in Fungal biology reviews (01-12-2020)“…Azole resistance is a concern for the management of diseases caused by Aspergillus fumigatus in humans. Azole fungicide use in the environment has been…”
Get full text
Journal Article -
13
Illuminating choices for library prep: a comparison of library preparation methods for whole genome sequencing of Cryptococcus neoformans using Illumina HiSeq
Published in PloS one (19-11-2014)“…The industry of next-generation sequencing is constantly evolving, with novel library preparation methods and new sequencing machines being released by the…”
Get full text
Journal Article -
14
Advances in Cryptococcus genomics: insights into the evolution of pathogenesis
Published in Memórias do Instituto Oswaldo Cruz (01-01-2018)“…Cryptococcus species are the causative agents of cryptococcal meningitis, a significant source of mortality in immunocompromised individuals. Initial work on…”
Get full text
Journal Article -
15
The human fungal pathogen Aspergillus fumigatus can produce the highest known number of meiotic crossovers
Published in PLoS biology (14-09-2023)“…Sexual reproduction involving meiosis is essential in most eukaryotes. This produces offspring with novel genotypes, both by segregation of parental…”
Get full text
Journal Article -
16
Surveillance for Azole-Resistant Aspergillus fumigatus in a Centralized Diagnostic Mycology Service, London, United Kingdom, 1998-2017
Published in Frontiers in microbiology (20-09-2018)“…is the leading cause of invasive aspergillosis. Treatment is hindered by the emergence of resistance to triazole antimycotic agents. Here, we present the…”
Get full text
Journal Article -
17
Accounting for the Biological Complexity of Pathogenic Fungi in Phylogenetic Dating
Published in Journal of fungi (Basel) (14-08-2021)“…In the study of pathogen evolution, temporal dating of phylogenies provides information on when species and lineages may have diverged in the past. When…”
Get full text
Journal Article -
18
Breaching Pathogeographic Barriers by the Bat White-Nose Fungus
Published in mBio (22-05-2018)“…Bat white-nose syndrome has become associated with unparalleled mortality in bat species across the United States since 2006. In a recent article, Drees and…”
Get full text
Journal Article -
19
A Population Genomics Approach to Assessing the Genetic Basis of Within-Host Microevolution Underlying Recurrent Cryptococcal Meningitis Infection
Published in G3 : genes - genomes - genetics (01-04-2017)“…Recurrence of meningitis due to after treatment causes substantial mortality in HIV/AIDS patients across sub-Saharan Africa. In order to determine whether…”
Get full text
Journal Article -
20
Cross-Disciplinary Genomics Approaches to Studying Emerging Fungal Infections
Published in Life (Basel, Switzerland) (28-11-2020)“…Emerging fungal pathogens pose a serious, global and growing threat to food supply systems, wild ecosystems, and human health. However, historic chronic…”
Get full text
Journal Article