Search Results - "Rhoden, Kerry J"
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Mutant MYO1F alters the mitochondrial network and induces tumor proliferation in thyroid cancer
Published in International journal of cancer (01-10-2018)“…Familial aggregation is a significant risk factor for the development of thyroid cancer and familial non‐medullary thyroid cancer (FNMTC) accounts for 5–7% of…”
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2
A novel missense mutation in ANO5/TMEM16E is causative for gnathodiaphyseal dyplasia in a large Italian pedigree
Published in European journal of human genetics : EJHG (01-06-2013)“…Gnathodiaphyseal dysplasia (GDD) is an autosomal dominant syndrome characterized by frequent bone fractures at a young age, bowing of tubular bones and…”
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3
Perfluorooctane sulfonic acid, a persistent organic pollutant, inhibits iodide accumulation by thyroid follicular cells in vitro
Published in Molecular and cellular endocrinology (15-09-2020)“…Poly- and perfluoroalkyl substances (PFAS) are a class of endocrine disrupting chemicals (EDCs) reported to alter thyroid function. Iodide uptake by thyroid…”
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4
Anoctamin 1 is Apically Expressed on Thyroid Follicular Cells and Contributes to ATP- and Calcium-Activated Iodide Efflux
Published in Cellular physiology and biochemistry (01-01-2014)“…Background/Aims: Iodide efflux from thyroid cells into the follicular lumen is essential for the synthesis of thyroid hormones, however, the pathways mediating…”
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Molecular pathology of thyroid tumours of follicular cells: a review of genetic alterations and their clinicopathological relevance
Published in Histopathology (01-01-2018)“…Thyroid cancer is the most common endocrine malignancy. Knowledge of the molecular pathology of thyroid tumours originating from follicular cells has greatly…”
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6
Seronegative Celiac Disease: Shedding Light on an Obscure Clinical Entity
Published in Digestive and liver disease (01-09-2016)“…Abstract Background Although serological tests are useful for identifying celiac disease, it is well established that a minority of celiacs are seronegative…”
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Features and Progression of Potential Celiac Disease in Adults
Published in Clinical gastroenterology and hepatology (01-05-2016)“…Background & Aims Individuals with potential celiac disease have serologic and genetic markers of the disease with little or no damage to the small intestinal…”
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Real-time quantitative RT-PCR identifies distinct c-RET, RET/PTC1 and RET/PTC3 expression patterns in papillary thyroid carcinoma
Published in Laboratory investigation (01-12-2004)“…RET/PTC1 and RET/PTC3 are the markers for papillary thyroid carcinoma. Their reported prevalence varies broadly. Nonrearranged c-RET has also been detected in…”
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BRAF V600E and risk stratification of thyroid microcarcinoma: a multicenter pathological and clinical study
Published in Modern pathology (01-10-2015)“…Studies from single institutions have analyzed BRAF in papillary microcarcinomas, sometimes with contradictory results. Most of them have provided limited…”
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BRAF Mutation Predicts a Poorer Clinical Prognosis for Papillary Thyroid Cancer
Published in The journal of clinical endocrinology and metabolism (01-12-2005)“…Context: Use of BRAF mutation in papillary thyroid cancer (PTC) has the potential to improve risk stratification of this cancer. Objective: The objective of…”
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RET/Papillary Thyroid Cancer Rearrangement in Nonneoplastic Thyrocytes: Follicular Cells of Hashimoto’s Thyroiditis Share Low-Level Recombination Events with a Subset of Papillary Carcinoma
Published in The journal of clinical endocrinology and metabolism (01-06-2006)“…Context: RET/papillary thyroid cancer (PTC) is a marker for papillary thyroid carcinoma, but its specificity has been questioned because of the disputed…”
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12
Prevalence of the single-nucleotide polymorphism rs11554137 (IDH1105GGT) in brain tumors of a cohort of Italian patients
Published in Scientific reports (13-03-2018)“…IDH mutational status is required for proper diagnosis according to the WHO criteria revised in 2016. The single nucleotide polymorphism (SNP) rs11554137 (…”
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13
Intracellular anion fluorescence assay for sodium/iodide symporter substrates
Published in Analytical biochemistry (01-08-2011)“…The sodium/iodide symporter (NIS) is primarily responsible for iodide accumulation in the thyroid gland for the synthesis of thyroid hormones; however, it can…”
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14
Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer
Published in International journal of cancer (15-11-2006)“…The role of aberrant tumor suppressor gene methylation in the aggressiveness of papillary thyroid cancer (PTC) has not been documented. By showing promoter…”
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15
Perchlorate transport and inhibition of the sodium iodide symporter measured with the yellow fluorescent protein variant YFP-H148Q/I152L
Published in Toxicology and applied pharmacology (15-03-2010)“…Perchlorate is an environmental contaminant that impairs thyroid function by interacting with the sodium iodide symporter (NIS), the transporter responsible…”
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BRAF(V600E) mutation and expression of proangiogenic molecular markers in papillary thyroid carcinomas
Published in European journal of endocrinology (01-09-2011)“…Tyrosine kinase inhibitors (TKIs) are evaluated for treatment of radioiodine refractory thyroid cancer. Their effects in this setting are based on blockade of…”
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17
Fluorescence quantitation of thyrocyte iodide accumulation with the yellow fluorescent protein variant YFP-H148Q/I152L
Published in Analytical biochemistry (15-02-2008)“…The thyroid gland accumulates iodide for the synthesis of thyroid hormones. The aim of the current study was to quantify iodide accumulation in cultured…”
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18
Inhibition of Vascular Smooth Muscle Tone by the H+, K+-ATPase Inhibitor SCH 28080
Published in Journal of pharmacy and pharmacology (01-07-2000)“…Vascular smooth muscle is thought to possess an H+‐K+ ATPase that contributes to the regulation of intracellular K+ concentration and pH. We have examined the…”
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Cell-based imaging of sodium iodide symporter activity with the yellow fluorescent protein variant YFP-H148Q/I152L
Published in American Journal of Physiology: Cell Physiology (01-02-2007)“…The sodium iodide symporter (NIS) mediates iodide (I(-)) transport in the thyroid gland and other tissues and is of increasing importance as a therapeutic…”
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BRAFV600E mutation and expression of proangiogenic molecular markers in papillary thyroid carcinomas
Published in European journal of endocrinology (01-09-2011)“…ObjectiveTyrosine kinase inhibitors (TKIs) are evaluated for treatment of radioiodine refractory thyroid cancer. Their effects in this setting are based on…”
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