Search Results - "Rhoades, Rodney"

Rho-Kinase Activation Is Involved in Hypoxia-Induced Pulmonary Vasoconstriction by Wang, Zhiqian, Jin, Najia, Ganguli, Supriya, Swartz, Darl R, Li, Liang, Rhoades, Rodney A

“…Rho-associated serine/threonine kinase (Rho-kinase) is a downstream effector of small GTPase RhoA that has recently been shown to play an important role in…”
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Heterotrimeric G proteins and the platelet-derived growth factor receptor-beta contribute to hypoxic proliferation of smooth muscle cells by Lannér, M Carita, Raper, Maggie, Pratt, Whitney M, Rhoades, Rodney A

“…Hypoxic proliferation of pulmonary arterial smooth muscle cells (PASMC) is mitogen dependent, but the signaling pathways mediating hypoxia-induced cell growth…”
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Migration of Vascular Smooth Muscle Cells Induced by Sphingosine 1-Phosphate and Related Lipids: Potential Role in the Angiogenic Response by Boguslawski, George, Grogg, Jeremy R., Welch, Zachary, Ciechanowicz, Sandra, Sliva, Daniel, Kovala, A.Thomas, McGlynn, Patrick, Brindley, David N., Rhoades, Rodney A., English, Denis

“…The bioactive lipids sphingosine 1-phosphate (SPP), sphingosylphosphorylcholine, and lysophosphatidic acid play an important role in angiogenesis as a result…”
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Augmentation of intrapericardial nitric oxide level by a prolonged-release nitric oxide donor reduces luminal narrowing after porcine coronary angioplasty by SANG HONG BAEK, HRABIE, Joseph A, KEEFER, Larry K, DONGMING HOU, FINEBERG, Naomi, RHOADES, Rodney, MARCH, Keith L

“…Nitric oxide (NO) is a potent vasodilator and antiplatelet agent that suppresses vascular smooth muscle cell proliferation. Hypothesizing that generating NO in…”
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Hypoxia Inhibits Myosin Phosphatase in Pulmonary Arterial Smooth Muscle Cells: Role of Rho-Kinase by Wang, Zhiqian, Lanner, M. Carita, Jin, Najia, Swartz, Darl, Li, Liang, Rhoades, Rodney A

“…Rho-kinase was recently found to phosphorylate the myosin-binding subunit (MBS) of myosin phosphatase (MP) and to regulate MP activity. Although myosin light…”
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Hypoxia Activates Jun-N-Terminal Kinase, Extracellular Signal-Regulated Protein Kinase, and p38 Kinase in Pulmonary Arteries by Jin, Najia, Hatton, Nathan, Swartz, Darl R, Xia, Xiao-ling, Harrington, Maureen A, Larsen, Steven H, Rhoades, Rodney A

“…Chronic alveolar hypoxia is the major cause of pulmonary hypertension. The cellular mechanisms involved in hypoxia- induced pulmonary arterial remodeling are…”
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Hydrogen Peroxide Stimulates Extracellular Signal-regulated Protein Kinases in Pulmonary Arterial Smooth Muscle Cells by Zhang, Jiahui, Jin, Najia, Liu, Yi, Rhoades, Rodney A

“…Hydrogen peroxide (H2O2) has emerged as an important intracellular signaling molecule and has been shown to stimulate the growth of vascular smooth muscle…”
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Activation of tyrosine kinases in H2O2-induced contraction in pulmonary artery by Jin, N, Rhoades, R A

“…Hydrogen peroxide (H2O2) is an important reactive oxygen species implicated in lung vascular constriction and injury. The purpose of this study was to…”
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H2O2-induced egr-1, fra-1, and c-jun gene expression is mediated by tyrosine kinase in aortic smooth muscle cells by Jin, Najia, Hatton, Nathan D, Harrington, Maureen A, Xia, Xiaolin, Larsen, Steve H, Rhoades, Rodney A

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Tıbbi fizyoloji: klinik tıbbın temelleri / Editörler, Rodney A. Rhoades, David R. Bell; çeviri editörü, Prof. Dr. Erdal Ağar; çeviri editör yardımcıları, Prof. Dr. Mustafa Ayyıldız, Prof. Dr. Mehmet Yıldırım by Rhoades, Rodney, Bell, David R, Ağar, Erdal, Ayyıldız, Mustafa, Yıldırım, Mehmet

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Heterotrimeric G Proteins and the Platelet-Derived Growth Factor Receptor-{beta} Contribute to Hypoxic Proliferation of Smooth Muscle Cells by Lanner, M. Carita, Raper, Maggie, Pratt, Whitney M, Rhoades, Rodney A

“…Hypoxic proliferation of pulmonary arterial smooth muscle cells (PASMC) is mitogen dependent, but the signaling pathways mediating hypoxia-induced cell growth…”
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Communication between tyrosine kinase pathway and myosin light chain kinase pathway in smooth muscle by Jin, N, Siddiqui, R A, English, D, Rhoades, R A

“…Two separate signal transduction pathways exist in vascular smooth muscle: one for cell growth, proliferation, and differentiation and the other for…”
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H 2O 2-induced egr-1, fra-1, and c-jun gene expression is mediated by tyrosine kinase in aortic smooth muscle cells by Jin, Najia, Hatton, Nathan D, Harrington, Maureen A, Xia, Xiaolin, Larsen, Steve H, Rhoades, Rodney A

“…Hydrogen peroxide (H 2O 2) has recently been shown to have a dual effect on cell growth by stimulating proliferation and triggering apoptosis. Apoptosis…”
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The response of lung tissue and surfactant to nitrogen dioxide exposure by Williams, R A, Rhoades, R A, Adams, W S

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Hypoxia-induced pulmonary arterial contraction appears to be dependent on myosin light chain phosphorylation by Zhao, Y, Rhoades, R A, Packer, C S

“…The signal transduction pathway of hypoxic pulmonary arterial contraction has not been elucidated. Phosphorylation of the 20-kDa myosin light chain (MLC20) is…”
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Influence of microtubules on vascular smooth muscle contraction by Zhang, D, Jin, N, Rhoades, R A, Yancey, K W, Swartz, D R

“…Microtubules are ubiquitous in eukaryotic cells and play key roles in many cellular activities. The purpose of this study was to investigate the influence of…”
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Microtubule disruption modulates the Rho-kinase pathway in vascular smooth muscle by Zhang, D, Wang, Z, Jin, N, Li, L, Rhoades, R A, Yancey, K W, Swartz, D R

“…Microtubules constitute one of the main cytoskeletal components in eukaryotic cells. Recent studies have shown that microtubule disruption induced significant…”
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The vein utilizes different sources of energy than the artery during pulmonary hypoxic vasoconstriction by Zhao, Y, Packer, C S, Rhoades, R A

“…Recent studies have shown that the contractile response to hypoxia is much greater in the pulmonary vein than in the artery. The purpose of this study was to…”
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Protective role of sulfhydryl reagents in oxidant lung injury by Patterson, C E, Rhoades, R A

“…Recently there has been a great deal of interest in exploring possible ways to protect the lung from oxidant damage. Since sulfhydryl compounds are among the…”
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Activated neutrophils alter contractile properties of the pulmonary artery by Patterson, C E, Jin, N, Packer, C S, Rhoades, R A

“…Activated neutrophils produce a wide array of products (free radicals, arachidonate metabolites, degradative enzymes), cause hemodynamic effects and increased…”
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