Search Results - "Rhind, Stewart M"
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Impact of endocrine-disrupting compounds (EDCs) on female reproductive health
Published in Molecular and cellular endocrinology (22-05-2012)“…Evidence is accumulating that environmental chemicals (ECs) including endocrine-disrupting compounds (EDCs) can alter female reproductive development,…”
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2
Evaluation of spot and passive sampling for monitoring, flux estimation and risk assessment of pesticides within the constraints of a typical regulatory monitoring scheme
Published in The Science of the total environment (01-11-2016)“…In many agricultural catchments of Europe and North America, pesticides occur at generally low concentrations with significant temporal variation. This poses…”
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3
Exposure to a Complex Cocktail of Environmental Endocrine-Disrupting Compounds Disturbs the Kisspeptin/GPR54 System in Ovine Hypothalamus and Pituitary Gland
Published in Environmental health perspectives (01-10-2009)“…Background: Ubiquitous environmental chemicals, including endocrine-disrupting chemicals (EDCs), are associated with declining human reproductive health, as…”
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4
Homozygosity for a single base-pair mutation in the oocyte-specific GDF9 gene results in sterility in Thoka sheep
Published in Reproduction (Cambridge, England) (01-12-2009)“…The control of fecundity is critical in determining mammalian offspring survival. It is regulated principally by the ovulation rate, so that primates and large…”
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Protein‐energy malnutrition during early gestation in sheep blunts fetal renal vascular and nephron development and compromises adult renal function
Published in The Journal of physiology (01-01-2012)“…Non‐technical summary A poor diet during pregnancy has been linked to long‐term health outcomes for the baby, such as an increased risk of diseases of the…”
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Exposure to chemical cocktails before or after conception – The effect of timing on ovarian development
Published in Molecular and cellular endocrinology (25-08-2013)“…•In-utero exposure to environmental chemicals disturbs ovary development.•We investigated differential effects of exposure before or after conception.•The…”
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Effects of pre-mating nutrition on mRNA levels of developmentally relevant genes in sheep oocytes and granulosa cells
Published in Reproduction (Cambridge, England) (01-09-2008)“…The present study was designed to investigate the relationship between pre-mating nutrition and the relative amounts of a panel of developmentally relevant…”
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Impact of sublethal levels of environmental pollutants found in sewage sludge on a novel Caenorhabditis elegans model biosensor
Published in PloS one (03-10-2012)“…A transgenic strain of the model nematode Caenorhabditis elegans in which bioluminescence reports on relative, whole-organism ATP levels was used to test an…”
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Effects of prenatal undernutrition on emotional reactivity and cognitive flexibility in adult sheep
Published in Behavioural brain research (05-05-2004)“…The experiment reported was designed to test two hypotheses: that prenatal undernutrition (a) increases emotional reactivity and (b) impairs cognitive…”
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A study on temporal trends and estimates of fate of Bisphenol A in agricultural soils after sewage sludge amendment
Published in The Science of the total environment (15-05-2015)“…Temporal concentration trends of BPA in soils were investigated following sewage sludge application to pasture (study 1: short term sludge application; study…”
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Simultaneous extraction and clean-up of polybrominated diphenyl ethers and polychlorinated biphenyls from sheep liver tissue by selective pressurized liquid extraction and analysis by gas chromatography–mass spectrometry
Published in Journal of Chromatography A (25-02-2011)“…We describe a selective pressurized liquid extraction (SPLE) method, followed by gas chromatography–mass spectrometry (GC–MS), for the simultaneous extraction…”
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Optimized determination of polybrominated diphenyl ethers and polychlorinated biphenyls in sheep serum by solid-phase extraction–gas chromatography–mass spectrometry
Published in Talanta (Oxford) (15-04-2011)“…We describe a solid-phase extraction (SPE) method, followed by gas chromatography–mass spectrometry (GC–MS), for the simultaneous determination of…”
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13
Effects of polychlorinated biphenyls in CD-1 mice: reproductive toxicity and intergenerational transmission
Published in Toxicological sciences (01-03-2012)“…Several studies indicate that in utero and perinatal exposure to polychlorinated biphenyls (PCBs) induces adverse reproductive effects, but it remains unclear…”
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Environmental chemicals impact dog semen quality in vitro and may be associated with a temporal decline in sperm motility and increased cryptorchidism
Published in Scientific reports (09-08-2016)“…Adverse temporal trends in human semen quality and cryptorchidism in infants have been associated with exposure to environmental chemicals (ECs) during…”
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In utero exposure to cigarette chemicals induces sex-specific disruption of one-carbon metabolism and DNA methylation in the human fetal liver
Published in BMC medicine (29-01-2015)“…Maternal smoking is one of the most important modifiable risk factors for low birthweight, which is strongly associated with increased cardiometabolic disease…”
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The fetal ovary exhibits temporal sensitivity to a ‘real-life’ mixture of environmental chemicals
Published in Scientific reports (02-03-2016)“…The development of fetal ovarian follicles is a critical determinant of adult female reproductive competence. Prolonged exposure to environmental chemicals…”
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Maternal undernutrition and the ovine acute phase response to vaccination
Published in BMC veterinary research (15-01-2008)“…The acute phase response is the immediate host response to infection, inflammation and trauma and can be monitored by measuring the acute phase proteins (APP)…”
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In utero exposure to cigarette smoke dysregulates human fetal ovarian developmental signalling
Published in Human reproduction (Oxford) (01-07-2014)“…How does maternal cigarette smoking disturb development of the human fetal ovary? Maternal smoking increases fetal estrogen titres and dysregulates several…”
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Selective pressurized liquid extraction of estrogenic compounds in soil and analysis by gas chromatography–mass spectrometry
Published in Analytica chimica acta (24-01-2011)“…A selective pressurized liquid extraction (SPLE) method, followed by gas chromatography–mass spectrometry (GC–MS), for the simultaneous extraction and clean-up…”
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In utero exposure to low doses of environmental pollutants disrupts fetal ovarian development in sheep
Published in Molecular human reproduction (01-05-2008)“…Epidemiological studies of the impact of environmental chemicals on reproductive health demonstrate consequences of exposure but establishing causative links…”
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