Search Results - "Rheinemann, Lara"
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In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein
Published in The Journal of experimental medicine (01-05-2017)“…Zoonotic transmission of influenza A viruses can give rise to devastating pandemics, but currently it is impossible to predict the pandemic potential of…”
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Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting
Published in Cell discovery (12-04-2024)Get full text
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NFE2 regulates transcription of multiple enzymes in the heme biosynthesis pathway
Published in Haematologica (Roma) (01-10-2014)Get full text
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Host-Virus Interactions during ESCRT-Dependent Virus Budding
Published 01-01-2021“…The endosomal sorting complexes required for transport (ESCRT) pathway mediates cellular membrane fission events such as multivesicular body formation and…”
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Interactions between AMOT PPxY motifs and NEDD4L WW domains function in HIV-1 release
Published in The Journal of biological chemistry (01-08-2021)“…Like most enveloped viruses, HIV must acquire a lipid membrane as it assembles and buds through the plasma membrane of infected cells to spread infection…”
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Recurrent evolution of an inhibitor of ESCRT-dependent virus budding and LINE-1 retrotransposition in primates
Published in Current biology (11-04-2022)“…Most antiviral proteins recognize specific features of viruses. In contrast, the recently described antiviral factor retroCHMP3 interferes with the “host…”
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Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization
Published in Journal of virology (01-11-2015)“…Many viruses affect or exploit the phosphatidylinositol-3-kinase (PI3K)-Akt-mammalian target of rapamycin (mTOR) pathway, a crucial prosurvival signaling…”
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RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis
Published in Cell (14-10-2021)“…Many enveloped viruses require the endosomal sorting complexes required for transport (ESCRT) pathway to exit infected cells. This highly conserved pathway…”
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174: Transgenic mice expressing interferon-regulated human influenza virus restriction factor MxA
Published in Cytokine (Philadelphia, Pa.) (01-11-2014)“…In mice, influenza virus resistance is strongly dependent on the interferon (IFN)-regulated Mx1 gene which encodes a potent restriction factor that inhibits a…”
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