Search Results - "Rhee, Siyeon"

Vein to artery: the first arteriogenesis in the mammalian embryo by Rhee, Siyeon, Wu, Joseph C.

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Single-Cell RNA Sequencing Unveils Unique Transcriptomic Signatures of Organ-Specific Endothelial Cells by Paik, David T., Tian, Lei, Williams, Ian M., Rhee, Siyeon, Zhang, Hao, Liu, Chun, Mishra, Ridhima, Wu, Sean M., Red-Horse, Kristy, Wu, Joseph C.

“…BACKGROUND:Endothelial cells (ECs) display considerable functional heterogeneity depending on the vessel and tissue in which they are located. Whereas these…”
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Endothelial cells respond to the direction of mechanical stimuli through SMAD signaling to regulate coronary artery size by Poduri, Aruna, Chang, Andrew H, Raftrey, Brian, Rhee, Siyeon, Van, Mike, Red-Horse, Kristy

“…How mechanotransduction intersects with chemical and transcriptional factors to shape organogenesis is an important question in developmental biology. This is…”
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Single-cell and spatial transcriptomics approaches of cardiovascular development and disease by Roth, Robert, Kim, Soochi, Kim, Jeesu, Rhee, Siyeon

“…Recent advancements in the resolution and throughput of single-cell analyses, including single-cell RNA sequencing (scRNA-seq), have achieved significant…”
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Untold story of human cervical cancers: HPV-negative cervical cancer by Lee, Jae-Eun, Chung, Yein, Rhee, Siyeon, Kim, Tae-Hyung

“…Cervical cancer is the fourth most common malignancy in women worldwide. Although infection from human papillomavirus (HPV) has been the leading cause of…”
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Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes by Buikema, Jan W., Lee, Soah, Goodyer, William R., Maas, Renee G., Chirikian, Orlando, Li, Guang, Miao, Yi, Paige, Sharon L., Lee, Daniel, Wu, Haodi, Paik, David T., Rhee, Siyeon, Tian, Lei, Galdos, Francisco X., Puluca, Nazan, Beyersdorf, Benjamin, Hu, James, Beck, Aimee, Venkamatran, Sneha, Swami, Srilatha, Wijnker, Paul, Schuldt, Maike, Dorsch, Larissa M., van Mil, Alain, Red-Horse, Kristy, Wu, Joy Y., Geisen, Caroline, Hesse, Michael, Serpooshan, Vahid, Jovinge, Stefan, Fleischmann, Bernd K., Doevendans, Pieter A., van der Velden, Jolanda, Garcia, K. Christopher, Wu, Joseph C., Sluijter, Joost P.G., Wu, Sean M.

“…Modulating signaling pathways including Wnt and Hippo can induce cardiomyocyte proliferation in vivo. Applying these signaling modulators to human induced…”
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Large-Scale Single-Cell RNA-Seq Reveals Molecular Signatures of Heterogeneous Populations of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells by Paik, David T, Tian, Lei, Lee, Jaecheol, Sayed, Nazish, Chen, Ian Y, Rhee, Siyeon, Rhee, June-Wha, Kim, Youngkyun, Wirka, Robert C, Buikema, Jan W, Wu, Sean M, Red-Horse, Kristy, Quertermous, Thomas, Wu, Joseph C

“…RATIONALE:Human induced pluripotent stem cell-derived endothelial cells (iPSC-ECs) have risen as a useful tool in cardiovascular research, offering a wide…”
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Identification of Lymphatic and Hematogenous Routes of Rapidly Labeled Radioactive and Fluorescent Exosomes through Highly Sensitive Multimodal Imaging by Jung, Kyung Oh, Kim, Young-Hwa, Chung, Seock-Jin, Lee, Chul-Hee, Rhee, Siyeon, Pratx, Guillem, Chung, June-Key, Youn, Hyewon

“…There has been considerable interest in the clinical use of exosomes as delivery vehicles for treatments as well as for promising diagnostic biomarkers, but…”
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Whole-body tracking of single cells via positron emission tomography by Jung, Kyung Oh, Kim, Tae Jin, Yu, Jung Ho, Rhee, Siyeon, Zhao, Wei, Ha, Byunghang, Red-Horse, Kristy, Gambhir, Sanjiv Sam, Pratx, Guillem

“…In vivo molecular imaging can measure the average kinetics and movement routes of injected cells through the body. However, owing to non-specific accumulation…”
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Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease by Rhee, Siyeon, Chung, Jae I., King, Devin A., D’amato, Gaetano, Paik, David T., Duan, Anna, Chang, Andrew, Nagelberg, Danielle, Sharma, Bikram, Jeong, Youngtae, Diehn, Maximilian, Wu, Joseph C., Morrison, Ashby J., Red-Horse, Kristy

“…During development, the formation of a mature, well-functioning heart requires transformation of the ventricular wall from a loose trabecular network into a…”
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IKKε-deficient macrophages impede cardiac repair after myocardial infarction by enhancing the macrophage–myofibroblast transition by Cho, Hyang Hee, Rhee, Siyeon, Cho, Dong Im, Jun, Ju Hee, Heo, HyoJung, Cho, Su Han, Kim, Dohyup, Wang, Mingqiang, Kang, Bo Gyeong, Yoo, Soo Ji, Cho, Meeyoung, Lim, Soo yeon, Cho, Jae Yeong, Jeong, In Seok, Kim, Yong Sook, Ahn, Youngkeun

“…The regulatory role of the inhibitor of NF-kB kinase ε (IKKε) in postmyocardial infarction (MI) inflammation remains uncertain. Using an MI mouse model, we…”
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miR-106a–363 cluster in extracellular vesicles promotes endogenous myocardial repair via Notch3 pathway in ischemic heart injury by Jung, Ji-Hye, Ikeda, Gentaro, Tada, Yuko, von Bornstädt, Daniel, Santoso, Michelle R., Wahlquist, Christine, Rhee, Siyeon, Jeon, Young-Jun, Yu, Anthony C., O’brien, Connor G., Red-Horse, Kristy, Appel, Eric A., Mercola, Mark, Woo, Joseph, Yang, Phillip C.

“…Endogenous capability of the post-mitotic human heart holds great promise to restore the injured myocardium. Recent evidence indicates that the extracellular…”
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An NKX-COUP-TFII morphogenetic code directs mucosal endothelial addressin expression by Dinh, Thanh Theresa, Xiang, Menglan, Rajaraman, Anusha, Wang, Yongzhi, Salazar, Nicole, Zhu, Yu, Roper, Walter, Rhee, Siyeon, Brulois, Kevin, O’Hara, Ed, Kiefel, Helena, Dinh, Truc M., Bi, Yuhan, Gonzalez, Dalila, Bao, Evan P., Red-Horse, Kristy, Balogh, Peter, Gábris, Fanni, Gaszner, Balázs, Berta, Gergely, Pan, Junliang, Butcher, Eugene C.

“…Immunoglobulin family and carbohydrate vascular addressins encoded by Madcam1 and St6gal1 control lymphocyte homing into intestinal tissues, regulating…”
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miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC by Jeon, Young-Jun, Kim, Taewan, Park, Dongju, Nuovo, Gerard J., Rhee, Siyeon, Joshi, Pooja, Lee, Bum-Kyu, Jeong, Johan, Suh, Sung-suk, Grotzke, Jeff E., Kim, Sung-Hak, Song, Jieun, Sim, Hosung, Kim, Yonghwan, Peng, Yong, Jeong, Youngtae, Garofalo, Michela, Zanesi, Nicola, Kim, Jonghwan, Liang, Guang, Nakano, Ichiro, Cresswell, Peter, Nana-Sinkam, Patrick, Cui, Ri, Croce, Carlo M.

“…Non-small cell lung carcinoma (NSCLC) is leading cause of cancer-related deaths in the world. The Tumor Suppressor Candidate 3 (TUSC3) at chromosome 8p22 known…”
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Single-cell murine genetic fate mapping reveals bipotential hepatoblasts and novel multi-organ endoderm progenitors by El Sebae, Gabriel K, Malatos, Joseph M, Cone, Mary-Kate E, Rhee, Siyeon, Angelo, Jesse R, Mager, Jesse, Tremblay, Kimberly D

“…The definitive endoderm (DE) is the embryonic germ layer that forms the gut tube and associated organs, including thymus, lungs, liver and pancreas. To…”
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In vivo molecular and single cell imaging by Hong, Seongje, Rhee, Siyeon, Jung, Kyung Oh

“…Molecular imaging is used to improve the disease diagnosis, prognosis, monitoring of treatment in living subjects. Numerous molecular targets have been…”
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Untold story of human cervical cancers: HPV-negative cervical cancer by Lee, Jae-Eun, Chung, Yein, Rhee, Siyeon, Kim, Tae-Hyung

“…Cervical cancer is the fourth most common malignancy in women worldwide. Although infection from human papillomavirus (HPV) has been the leading cause of…”
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Single-cell and spatial transcriptomics approaches of cardiovascular development and disease by Roth, Robert, Kim, Soochi, Kim, Jeesu, Rhee, Siyeon

“…Recent advancements in the resolution and throughput of single-cell analyses, including single-cell RNA sequencing (scRNA-seq), have achieved significant…”
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Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development by Rhee, Siyeon, Guerrero-Zayas, Mara-Isel, Wallingford, Mary C, Ortiz-Pineda, Pablo, Mager, Jesse, Tremblay, Kimberly D

“…Mouse embryos lacking the polycomb group gene member Yin-Yang1 (YY1) die during the peri-implantation stage. To assess the post-gastrulation role of YY1, a…”
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Effects of trans-10,cis-12 conjugated linoleic acid on body composition in genetically obese mice by Hur, Sunjin, Whitcomb, Faith, Rhee, Siyeon, Park, Yooheon, Good, Deborah J, Park, Yeonhwa

“…Conjugated linoleic acid (CLA) has shown a number of biologically beneficial effects, including prevention of obesity. The purpose of this study was to test…”
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