Search Results - "Rhee, Seungshin"

Phase 1 study of the E-selectin inhibitor GMI 1070 in patients with sickle cell anemia by Wun, Ted, Styles, Lori, DeCastro, Laura, Telen, Marilyn J, Kuypers, Frans, Cheung, Anthony, Kramer, William, Flanner, Henry, Rhee, Seungshin, Magnani, John L, Thackray, Helen

“…Sickle cell anemia is an inherited disorder of hemoglobin that leads to a variety of acute and chronic complications. Abnormal cellular adhesion, mediated in…”
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An Open Label Study in Adults with Atopic Dermatitis to Assess Immune Response to Fluzone® Intradermal Vaccine by Leung, Donald Y.M., MD, PhD, Cheadle, Chris, PhD, Streib, Joanne, BA, Madigan, Trudi, RN, Leung, Susan B., RN, Bronchick, Caroline, RN, Rhee, Seungshin, MS, Barnes, Kathleen C., PhD, FAAAAI, David, Gloria, PhD, Weinberg, Adriana, MD

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Biomarkers of Disease Severity and Th2 Polarity Are Predictors of Atopic Dermatitis Subjects Who Are Colonized with S. Aureus by Beck, Lisa A., MD, FAAAAI, Yoshida, Takeshi, PhD, De Benedetto, Anna, MD, FAAAAI, Rhee, Seungshin, MS, Kuo, I-Hsin, MS, Reese, Jamie, David, Gloria, PhD, Schneider, Lynda C., MD FAAAAI, Paller, Amy, MD, Hanifin, Jon M., MD FAAAAI, Boguniewicz, Mark, MD, FAAAAI, Barnes, Kathleen C., PhD FAAAAI, Leung, Donald Y.M., MD, PhD, FAAAAI

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Randomized phase 2 study of GMI-1070 in SCD: reduction in time to resolution of vaso-occlusive events and decreased opioid use by Telen, Marilyn J., Wun, Ted, McCavit, Timothy L., De Castro, Laura M., Krishnamurti, Lakshmanan, Lanzkron, Sophie, Hsu, Lewis L., Smith, Wally R., Rhee, Seungshin, Magnani, John L., Thackray, Helen

“…Treatment of vaso-occlusive crises (VOC) or events in sickle cell disease (SCD) remains limited to symptom relief with opioids. Animal models support the…”
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Health‐related quality of life in adults with sickle cell disease (SCD): A report from the comprehensive sickle cell centers clinical trial consortium by Dampier, Carlton, LeBeau, Petra, Rhee, Seungshin, Lieff, Susan, Kesler, Karen, Ballas, Samir, Rogers, Zora, Wang, Winfred

“…Adults with Sickle Cell Disease (SCD) experience multiple disease-related complications, but few studies have examined relationships between these events and…”
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Health-related quality of life in children with sickle cell disease: A report from the Comprehensive Sickle Cell Centers Clinical Trial Consortium by Dampier, Carlton, Lieff, Susan, LeBeau, Petra, Rhee, Seungshin, McMurray, Marsha, Rogers, Zora, Smith-Whitley, Kim, Wang, Winfred

“…Background Pediatric health‐related quality of life (HRQOL) questionnaires have been validated in children with sickle cell disease (SCD), but small sample…”
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Pan-Selectin Antagonist Rivipansel (GMI-1070) Reduces Soluble E-Selectin Levels While Improving Clinical Outcomes in SCD Vaso-Occlusive Crisis by Wun, Ted, Telen, Marilyn J., Krishnamurti, Lakshmanan, McCavit, Timothy L., DeCastro, Laura M, Flanner, Henry, Kuypers, Frans A., Larkin, Sandra K., Rhee, Seungshin, Magnani, John L., Thackray, Helen M.

“…Introduction: The pan-selectin antagonist rivipansel (GMI-1070) reduced intravascular arrest of red/white blood cell aggregates and improved blood flow and…”
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Effects Of GMI 1070, a Pan-Selectin Inhibitor, On Pain Intensity and Opioid Utilization In Sickle Cell Disease by De Castro, Laura M., Wun, Ted, Lanzkron, Sophie, Smith, Wally R., Hassell, Kathryn L., Kutlar, Abdullah, Smith-Whitley, Kim, Rhee, Seungshin, Telen, Marilyn J., Thackray, Helen

“…▪ Management of acute, painful vaso-occlusive crisis (VOC), the hallmark of sickle cell disease (SCD), continues to be limited to symptomatic relief with oral…”
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Tapered oral dexamethasone for the acute chest syndrome of sickle cell disease by Quinn, Charles T., Stuart, Marie J., Kesler, Karen, Ataga, Kenneth I., Wang, Winfred C., Styles, Lori, Smith‐Whitley, Kim, Wun, Ted, Raj, Ashok, Hsu, Lewis L., Krishnan, Suba, Kuypers, Frans A., Setty, Yamaja, Rhee, Seungshin, Key, Nigel S., Buchanan, George R.

“…Summary Tapered oral dexamethasone for acute chest syndrome (ACS) in sickle cell anaemia was studied using a novel ACS assessment tool and investigational…”
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GMI 1070: Reduction In Time To Resolution Of Vaso-Occlusive Crisis and Decreased Opioid Use In a Prospective, Randomized, Multi-Center Double Blind, Adaptive Phase 2 Study In Sickle Cell Disease by Telen, Marilyn J., Wun, Ted, McCavit, Timothy L., De Castro, Laura M., Krishnamurti, Lakshmanan, Lanzkron, Sophie, Hsu, Lewis L., Smith, Wally R., Rhee, Seungshin, Magnani, John L., Thackray, Helen

“…Treatment for vaso-occlusive crisis (VOC) in sickle cell disease (SCD) remains supportive, focusing largely on symptom relief with opioids. Animal models have…”
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An Analysis Of The Pediatric Sub-Group From The Phase 2 Study Of GMI 1070 – A Novel Agent For The Vaso-Occlusive Crisis Of Sickle Cell Anemia by McCavit, Timothy L., Krishnamurti, Lakshmanan, Hsu, Lewis L., Quinn, Charles T., Odame, Isaac, Alvarez, Ofelia A., Driscoll, Catherine, Smith-Whitley, Kim, Rhee, Seungshin, Wun, Ted, Telen, Marilyn J., Thackray, Helen

“…▪ Vaso-occlusive crisis (VOC) is the hallmark of sickle cell anemia (SCA), yet VOC treatment has not improved in decades. Recently the role of adhesive…”
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A Pilot Study of Tapered Oral Dexamethasone for the Acute Chest Syndrome of Sickle Cell Disease by Quinn, Charles T., Stuart, Marie J., Kesler, Karen, Ataga, Kenneth I., Wang, Winfred C., Styles, Lori, Smith-Whitley, Kim, Wun, Ted, Krishnan, Suba, Kuypers, Frans A., Setty, Yamaja, Key, Nigel S., Rhee, Seungshin, Buchanan, George R.

“…Abstract 1515 Poster Board I-538 Acute chest syndrome (ACS) is a common cause of morbidity and mortality for individuals with sickle cell disease (SCD). The…”
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Local Linear Discriminant Analysis (LLDA) for group and region of interest (ROI)-based fMRI analysis by McKeown, Martin J., Li, Junning, Huang, Xuemei, Lewis, Mechelle M., Rhee, Seungshin, Young Truong, K.N., Wang, Z. Jane

“…A post-processing method for group discriminant analysis of fMRI is proposed. It assumes that the fMRI data have been pre-processed and analyzed so that each…”
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