Search Results - "Reznick, M"

The role of AMP-activated protein kinase in mitochondrial biogenesis by Reznick, Richard M., Shulman, Gerald I.

“…While it has been known for more than 75 years that physical activity is associated with increased mitochondrial content in muscle, the molecular mechanism for…”
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Aging-Associated Reductions in AMP-Activated Protein Kinase Activity and Mitochondrial Biogenesis by Reznick, Richard M., Zong, Haihong, Li, Ji, Morino, Katsutaro, Moore, Irene K., Yu, Hannah J., Liu, Zhen-Xiang, Dong, Jianying, Mustard, Kirsty J., Hawley, Simon A., Befroy, Douglas, Pypaert, Marc, Hardie, D. Grahame, Young, Lawrence H., Shulman, Gerald I.

“…Recent studies have demonstrated a strong relationship between aging-associated reductions in mitochondrial function, dysregulated intracellular lipid…”
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Paradoxical effects of increased expression of PGC-1α on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism by Choi, Cheol Soo, Befroy, Douglas E, Codella, Roberto, Kim, Sheene, Reznick, Richard M, Hwang, Yu-Jin, Liu, Zhen-Xiang, Lee, Hui-Young, Distefano, Alberto, Samuel, Varman T, Zhang, Dongyan, Cline, Gary W, Handschin, Christoph, Lin, Jiandie, Petersen, Kitt F, Spiegelman, Bruce M, Shulman, Gerald I

“…Peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α has been shown to play critical roles in regulating mitochondria biogenesis, respiration, and…”
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Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity by Choi, Cheol Soo, Savage, David B, Abu-Elheiga, Lutfi, Liu, Zhen-Xiang, Kim, Sheene, Kulkarni, Ameya, Distefano, Alberto, Hwang, Yu-Jin, Reznick, Richard M, Codella, Roberto, Zhang, Dongyan, Cline, Gary W, Wakil, Salih J, Shulman, Gerald I

“…Acetyl-CoA carboxylase 2 (ACC)2 is a key regulator of mitochondrial fat oxidation. To examine the impact of ACC2 deletion on whole-body energy metabolism, we…”
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Overexpression of uncoupling protein 3 in skeletal muscle protects against fat-induced insulin resistance by Choi, Cheol Soo, Fillmore, Jonathan J, Kim, Jason K, Liu, Zhen-Xiang, Kim, Sheene, Collier, Emily F, Kulkarni, Ameya, Distefano, Alberto, Hwang, Yu-Jin, Kahn, Mario, Chen, Yan, Yu, Chunli, Moore, Irene K, Reznick, Richard M, Higashimori, Takamasa, Shulman, Gerald I

“…Insulin resistance is a major factor in the pathogenesis of type 2 diabetes and is strongly associated with obesity. Increased concentrations of intracellular…”
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Muscle-Specific IRS-1 Ser→Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle by MORINO, Katsutaro, NESCHEN, Susanne, WHITE, Morris, PHILBRICK, William, SHULMAN, Gerald I, BILZ, Stefan, SONO, Saki, TSIRIGOTIS, Dimitrios, REZNICK, Richard M, MOORE, Irene, NAGAI, Yoshio, SAMUEL, Varman, SEBASTIAN, David

“…Muscle-Specific IRS-1 Ser→Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle Katsutaro Morino 1 2 , Susanne Neschen 1 2 ,…”
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Defects in Adaptive Energy Metabolism with CNS-Linked Hyperactivity in PGC-1α Null Mice by Lin, Jiandie, Wu, Pei-Hsuan, Tarr, Paul T., Lindenberg, Katrin S., St-Pierre, Julie, Zhang, Chen-yu, Mootha, Vamsi K., Jäger, Sibylle, Vianna, Claudia R., Reznick, Richard M., Cui, Libin, Manieri, Monia, Donovan, Mi X., Wu, Zhidan, Cooper, Marcus P., Fan, Melina C., Rohas, Lindsay M., Zavacki, Ann Marie, Cinti, Saverio, Shulman, Gerald I., Lowell, Bradford B., Krainc, Dimitri, Spiegelman, Bruce M.

“…PGC-1α is a coactivator of nuclear receptors and other transcription factors that regulates several metabolic processes, including mitochondrial biogenesis and…”
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In vivo suppression of plasma IL-12 levels by acute and chronic stress paradigms: Potential mediating mechanisms and sex differences by Shaashua, L, Sominsky, L, Levi, B, Sorski, L, Reznick, M, Page, G.G, Ben-Eliyahu, S

“…Highlight ► Behavioral stressors, surgery, and stress hormones reduce baseline plasma IL-12 levels, novel effects that were not all evident in the induced…”
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In vivo suppression of IL-12 plasma levels by various stress paradigms in rats: Multiple mediating neuroendocrine mechanisms by Shaashua, L, Reznick, M, Ben-Eliyahu, S

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"Government and Manners": Cosmopolitanism and the "Spirit" of Liberal Democracy in The Federalist and Charles Brockden Brown's Ormond by REZNICK, SCOTT M.

“…This article attempts an interpretive reorientation toward Charles Brockden Brown's gothic novel Ormond by examining the eighteenth-century political ideas it…”
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'Government and Manners': Cosmopolitanism and the 'Spirit' of Liberal Democracy in The Federalist and Charles Brockden Brown' s Ormond by Reznick, Scott M

“…Abstract This article attempts an interpretive reorientation toward Charles Brockden Brown's gothic novel Ormond by examining the eighteenth-century political…”
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Sacituzumab Govitecan Versus Docetaxel for Previously Treated Advanced or Metastatic Non-Small Cell Lung Cancer: The Randomized, Open-Label Phase III EVOKE-01 Study by Paz-Ares, Luis G, Juan-Vidal, Oscar, Mountzios, Giannis S, Felip, Enriqueta, Reinmuth, Niels, de Marinis, Filippo, Girard, Nicolas, Patel, Vipul M, Takahama, Takayuki, Owen, Scott P, Reznick, Douglas M, Badin, Firas B, Cicin, Irfan, Mekan, Sabeen, Patel, Riddhi, Zhang, Eric, Karumanchi, Divyadeep, Garassino, Marina Chiara

“…The open-label, phase III EVOKE-01 study evaluated sacituzumab govitecan (SG) versus standard-of-care docetaxel in metastatic non-small cell lung cancer…”
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Poetry Wars: Verse and Politics in the American Revolution and Early Republic by Colin Wells (review) by Reznick, Scott M

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On Liberty and Union: Moral Imagination and Its Limits in Daniel Webster’s Seventh of March Speech by REZNICK, SCOTT M.

“…Daniel Webster’s speech before the Senate on March 7, 1850, in support of the measures that would ultimately constitute the Compromise of 1850 has long been…”
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Muscle fibre type and size, and muscle capillary density in young double-muscled blue Belgian cattle by Stavaux, D, Art, T, McEntee, K, Reznick, M, Lekeux, P

“…Bovine muscle biopsies were analysed for fiber type and capillary density by the acid ATP-ase and amylase-PAS methods respectively. Samples obtained from…”
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"The Vision of Principles": Liberal Democracy and the Roots of Moral Experience in Antebellum American Literature by Reznick, Scott M

“…This dissertation analyzes the way in which antebellum writers participated in and helped shape the tradition of political liberalism. Emphasizing the dynamics…”
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A case of depressive neurosis following aortocoronary artery bypass surgery by Reznick, S M

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Poetry Wars: Verse and Politics in the American Revolution and Early Republic by REZNICK, SCOTT M.

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Orthopedic boot camp: Examining the effectiveness of an intensive surgical skills course by Sonnadara, Ranil R., PhD, Van Vliet, Aaron, MD, Safir, Oleg, MD, Alman, Benjamin, MD, Ferguson, Peter, MD, Kraemer, William, MD, Reznick, Richard, MD

“…Background Changes in health care across the globe have had a profound impact on the number of hands-on surgical training opportunities that are available to…”
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Gastrointestinal Endoscopy Competency Assessment Tool: development of a procedure-specific assessment tool for colonoscopy by Walsh, Catharine M., MD, MEd, FRCPC, Ling, Simon C., MB, ChB, MRCP (UK), Khanna, Nitin, MD, FRCPC, Cooper, Mary Anne, MD, MSc, MEd, FRCPC, Grover, Samir C., MD, MEd, FRCPC, May, Gary, MD, FRCPC, FASGE, Walters, Thomas D., MD, MBBChir, MRCP, Rabeneck, Linda, MD, MPH, FRCPC, Reznick, Richard, MD, MEd, FRCSC, FACS, Carnahan, Heather, PhD

“…Background Ensuring competence remains a seminal objective of endoscopy training programs, professional organizations, and accreditation bodies; however, no…”
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