Search Results - "Rezki, Nadjet"

A Green Ultrasound Synthesis, Characterization and Antibacterial Evaluation of 1,4-Disubstituted 1,2,3-Triazoles Tethering Bioactive Benzothiazole Nucleus by Rezki, Nadjet

“…The synthesis of N-(benzo[d]thiazol-2-yl)-2-(4-substituted-1H-1,2,3-triazol-1-yl)acetamides 5a-r via the 1,3-dipolar cycloaddition reaction between…”
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Design and Synthesis of Novel Imidazole Derivatives Possessing Triazole Pharmacophore with Potent Anticancer Activity, and In Silico ADMET with GSK-3β Molecular Docking Investigations by Al-Blewi, Fawzia, Shaikh, Salma Akram, Naqvi, Arshi, Aljohani, Faizah, Aouad, Mohamed Reda, Ihmaid, Saleh, Rezki, Nadjet

“…A library of novel imidazole-1,2,3-triazole hybrids were designed and synthesized based on the hybrid pharmacophore approach. Therefore, copper(I)catalyzed…”
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Green ultrasound-assisted three-component click synthesis of novel 1H-1,2,3-triazole carrying benzothiazoles and fluorinated-1,2,4-triazole conjugates and their antimicrobial evaluation by Rezki, Nadjet, Aouad, Mohamed Reda

“…The present study describes an efficient and ecofriendly, ultrasound, one-pot click cycloaddition approach for the construction of a novel series of…”
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Sulfadiazine analogs: anti-Toxoplasma in vitro study of sulfonamide triazoles by Arafa, Fadwa M, Osman, Doaa Hassan, Tolba, Mona Mohamed, Rezki, Nadjet, Aouad, Mohamed R, Hagar, Mohamed, Osman, Mervat, Said, Heba

“…Toxoplasmosis is an infection that prevails all over the world and is caused by the obligate intracellular protozoan parasite Toxoplasma gondii (T. gondii)…”
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Microwave and conventional synthesis of ester based dicationic pyridinium ionic liquids carrying hydrazone linkage: DNA binding, anticancer and docking studies by Al-Sodies, Salsabeel A., Aouad, Mohamed Reda, Ihmaid, Saleh, Aljuhani, Ateyatallah, Messali, Mouslim, Ali, Imran, Rezki, Nadjet

“…Novel task dicationic ionic liquids (Ts-DiILs) 6–29 were designed and synthesized, under both conventional and microwave conditions; through molecular…”
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Design, Synthesis, Molecular Modeling, Anticancer Studies, and Density Functional Theory Calculations of 4-(1,2,4-Triazol-3-ylsulfanylmethyl)-1,2,3-triazole Derivatives by Al Sheikh Ali, Adeeb, Khan, Daoud, Naqvi, Arshi, Al-Blewi, Fawzia Faleh, Rezki, Nadjet, Aouad, Mohamed Reda, Hagar, Mohamed

“…New conjugates of substituted 1,2,3-triazoles linked to 1,2,4-triazoles were synthesized starting from the appropriate S-propargylated 1,2,4-triazoles and …”
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Anticorrosive performance of newly synthesized dipyridine based ionic liquids by experimental and theoretical approaches by Moustafa, Amira Hossam Eldin, Abdel-Rahman, Hanaa H., Hagar, Mohamed, Aouad, Mohamed R., Rezki, Nadjet, Bishr, Sherif A. A.

“…Two newly synthetic nontoxic dipyridine-based ionic liquids (P ILs ) with the same chain lengths and different polar groups were investigated:…”
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Phenylpyrazolone-1,2,3-triazole Hybrids as Potent Antiviral Agents with Promising SARS-CoV-2 Main Protease Inhibition Potential by Musa, Arafa, Abulkhair, Hamada S, Aljuhani, Ateyatallah, Rezki, Nadjet, Abdelgawad, Mohamed A, Shalaby, Khaled, El-Ghorab, Ahmed H, Aouad, Mohamed R

“…COVID-19 infection is now considered one of the leading causes of human death. As an attempt towards the discovery of novel medications for the COVID-19…”
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Design, synthesis, in silico and in vitro antimicrobial screenings of novel 1,2,4-triazoles carrying 1,2,3-triazole scaffold with lipophilic side chain tether by Aouad, Mohamed Reda, Mayaba, Mariem Mohammed, Naqvi, Arshi, Bardaweel, Sanaa K., Al-blewi, Fawzia Faleh, Messali, Mouslim, Rezki, Nadjet

“…Background 1,2,4-Triazoles and 1,2,3-triazoles have gained significant importance in medicinal chemistry. Results This study describes a green, efficient and…”
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Halting Tumor Progression via Novel Non-Hydroxamate Triazole-Based Mannich Bases MMP-2/9 Inhibitors; Design, Microwave-Assisted Synthesis, and Biological Evaluation by Albelwi, Fawzia Faleh, Teleb, Mohamed, Abu-Serie, Marwa M., Moaty, Mohamed Nabil Abd Al, Alsubaie, Mai S., Zakaria, Mohamed A., El Kilany, Yeldez, Aouad, Mohamed Reda, Hagar, Mohamed, Rezki, Nadjet

“…Matrix metalloproteinases (MMPs) are key signaling modulators in the tumor microenvironment. Among MMPs, MMP-2 and MMP-9 are receiving renewed interest as…”
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Exploring the Antiparasitic Activity of Tris -1,3,4-Thiadiazoles against Toxoplasma gondii -Infected Mice by Almutairi, Tahani M, Rezki, Nadjet, Aouad, Mohamed Reda, Hagar, Mohamed, Bakr, Basant A, Hamed, Moaaz T, Hassen, Maha Khairy, Elwakil, Bassma H, Moneer, Esraa Abdelhamid

“…Nitrogen-containing atoms in their core structures have been exclusive building blocks in drug discovery and development. One of the most significant and…”
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Synthesis of Novel 2,5-Disubstituted-1,3,4-thiadiazoles Clubbed 1,2,4-Triazole, 1,3,4-Thiadiazole, 1,3,4-Oxadiazole and/or Schiff Base as Potential Antimicrobial and Antiproliferative Agents by Rezki, Nadjet, Al-Yahyawi, Amjad M, Bardaweel, Sanaa K, Al-Blewi, Fawzia F, Aouad, Mohamed R

“…In the present study, a new series of 2,5-disubstituted-1,3,4-thiadiazole tethered 1,2,4-triazole, 1,3,4-thiadiazole, 1,3,4-oxadiazole and Schiff base…”
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Novel Hybrid 1,2,4- and 1,2,3-Triazoles Targeting Mycobacterium Tuberculosis Enoyl Acyl Carrier Protein Reductase (InhA): Design, Synthesis, and Molecular Docking by El Sawy, Maged A, Elshatanofy, Maram M, El Kilany, Yeldez, Kandeel, Kamal, Elwakil, Bassma H, Hagar, Mohamed, Aouad, Mohamed Reda, Albelwi, Fawzia Faleh, Rezki, Nadjet, Jaremko, Mariusz, El Ashry, El Sayed H

“…Tuberculosis (TB) caused by Mycobacterium tuberculosis is still a serious public health concern around the world. More treatment strategies or more specific…”
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Synthesis, Characterization and Nanoformulation of Novel Sulfonamide-1,2,3-triazole Molecular Conjugates as Potent Antiparasitic Agents by Aljohani, Faizah S, Rezki, Nadjet, Aouad, Mohamed R, Elwakil, Bassma H, Hagar, Mohamed, Sheta, Eman, Hussein Mogahed, Nermine Mogahed Fawzy, Bardaweel, Sanaa K, Hagras, Nancy Abd-Elkader

“…( ) is a highly prevalent parasite that has no gold standard treatment due to the poor action or the numerous side effects. Focused sulfonamide-1,2,3-triazole…”
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Exploring of N-phthalimide-linked 1,2,3-triazole analogues with promising -anti-SARS-CoV-2 activity: synthesis, biological screening, and molecular modelling studies by Aljuhani, Ateyatallah, Alsehli, Mosa, Seleem, Mohamed A, Alraqa, Shaya Y, Ahmed, Hany E A, Rezki, Nadjet, Aouad, Mohamed R

“…In this study, a library of phthalimide Schiff base linked to 1,4-disubstituted-1,2,3-triazoles was designed, synthesised, and characterised by different…”
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Design, Synthesis and Anticancer Screening of Novel Benzothiazole-Piperazine-1,2,3-Triazole Hybrids by Aouad, Mohamed R, Soliman, Moataz A, Alharbi, Muath O, Bardaweel, Sanaa K, Sahu, Pramod K, Ali, Adeeb A, Messali, Mouslim, Rezki, Nadjet, Al-Soud, Yaseen A

“…A library of novel regioselective 1,4-di and 1,4,5-trisubstituted-1,2,3-triazole based benzothiazole-piperazine conjugates were designed and synthesized using…”
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Design, synthesis, ADME prediction and pharmacological evaluation of novel benzimidazole-1,2,3-triazole-sulfonamide hybrids as antimicrobial and antiproliferative agents by Al-blewi, Fawzia Faleh, Almehmadi, Meshal A., Aouad, Mohamed Reda, Bardaweel, Sanaa K., Sahu, Pramod K., Messali, Mouslim, Rezki, Nadjet, El Ashry, El Sayed H.

“…Background Nitrogen heterocyclic rings and sulfonamides have attracted attention of several researchers. Results A series of regioselective imidazole-based…”
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1,2,3-Triazole-Benzofused Molecular Conjugates as Potential Antiviral Agents against SARS-CoV-2 Virus Variants by Al-Humaidi, Jehan Y., Shaaban, Marwa M., Rezki, Nadjet, Aouad, Mohamed R., Zakaria, Mohamed, Jaremko, Mariusz, Hagar, Mohamed, Elwakil, Bassma H.

“…SARS-CoV-2 and its variants, especially the Omicron variant, remain a great threat to human health. The need to discover potent compounds that may control the…”
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Dicationic Bis-Pyridinium Hydrazone-Based Amphiphiles Encompassing Fluorinated Counteranions: Synthesis, Characterization, TGA-DSC, and DFT Investigations by Aljuhani, Ateyatallah, Rezki, Nadjet, Al-Sodies, Salsabeel, Messali, Mouslim, ElShafei, Gamal M S, Hagar, Mohamed, Aouad, Mohamed R

“…Quaternization and metathesis approaches were used to successfully design and synthesize the targeted dicationic bis-dipyridinium hydrazones carrying long…”
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Novel Dipyridinium Lipophile-Based Ionic Liquids Tethering Hydrazone Linkage: Design, Synthesis and Antitumorigenic Study by Al-Sodies, Salsabeel, Rezki, Nadjet, Albelwi, Fawzia Faleh, Messali, Mouslim, Aouad, Mohamed R, Bardaweel, Sanaa K, Hagar, Mohamed

“…Novel dicationic pyridinium ionic liquids tethering amphiphilic long alkyl side chains and fluorinated counter anions have been successfully synthesized by…”
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