Search Results - "Rezk, Abdelrahman I"
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Near-Infrared Responsive Synergistic Chemo-Phototherapy from Surface-Functionalized Poly(ε-caprolactone)–Poly(d,l‑lactic-co-glycolic acid) Composite Nanofibers for Postsurgical Cancer Treatment
Published in Biomacromolecules (12-09-2022)“…The combination of hyperthermia and chemotherapy has attracted significant attention in local cancer treatment following surgical resection. Pyrrole is a…”
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Poly(ε-Caprolactone)/Poly(Glycerol Sebacate) Composite Nanofibers Incorporating Hydroxyapatite Nanoparticles and Simvastatin for Bone Tissue Regeneration and Drug Delivery Applications
Published in Polymers (12-11-2020)“…Herein, we report a drug eluting scaffold composed of a composite nanofibers of poly(ε-caprolactone) (PCL) and poly(glycerol sebacate) (PGS) loaded with…”
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Bi-layered Nanofibers Membrane Loaded with Titanium Oxide and Tetracycline as Controlled Drug Delivery System for Wound Dressing Applications
Published in Polymers (01-10-2019)“…The aim of this study is to develop a novel functional bi-layered membrane loaded titanium oxide (TiO2) and tetracycline (TTC) for application in wound…”
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A Novel Design of Tri-Layer Membrane with Controlled Delivery of Paclitaxel and Anti-Biofilm Effect for Biliary Stent Applications
Published in Nanomaterials (Basel, Switzerland) (14-02-2021)“…Here, we developed a novel biliary stent coating material that is composed of tri-layer membrane with dual function of sustained release of paclitaxel (PTX)…”
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Drug release and kinetic models of anticancer drug (BTZ) from a pH-responsive alginate polydopamine hydrogel: Towards cancer chemotherapy
Published in International journal of biological macromolecules (01-12-2019)“…A pH-sensitive polymeric carrier was developed in this study for local delivery of anticancer drug bortezomib (BTZ) to cancer cells. Our strategy is based on…”
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Polyaniline-coated titanium oxide nanoparticles and simvastatin-loaded poly(ε-caprolactone) composite nanofibers scaffold for bone tissue regeneration application
Published in Colloids and surfaces, B, Biointerfaces (01-08-2020)“…[Display omitted] •A novel composite nanofiber loaded with simvastatin and TiO2/PANI was developed by electrospinning method.•Wettability and drug release were…”
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Strategically Designed Bifunctional Polydopamine Enwrapping Polycaprolactone-Hydroxyapatite-Doxorubicin Composite Nanofibers for Osteosarcoma Treatment and Bone Regeneration
Published in ACS applied materials & interfaces (26-04-2024)“…This study presents a new multifunctional nanofibrous drug delivery system to provide effective combination therapy with enormous potential for the treatment…”
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In-situ cellulose-framework templates mediated monodispersed silver nanoparticles via facile UV-light photocatalytic activity for anti-microbial functionalization
Published in Carbohydrate polymers (01-10-2021)“…Cellulose is well known as a biocompatible material or natural reducing material. In this study, As an eco-friendly and facile method, we prepared…”
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Rational design of bone extracellular matrix mimicking tri-layered composite nanofibers for bone tissue regeneration
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (15-10-2018)“…•Unique design of a tri-layered composite nanofiber scaffold mimicking the bone ECM.•Single scaffold for bone regeneration and osteogenic drug…”
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Nanographene-Au fine-tuning to intensify plasmonic-resonance of polymeric hybrid bionanosystem for synergistic phototherapy and nerve photobiomodulation
Published in Colloids and surfaces, B, Biointerfaces (01-05-2024)“…Here, we report the multi-photo-bioactivity of the plasmonic-nano graphitic coordinated polycaprolactone-based aligned nanofibrous scaffolds-based…”
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Composite PCL/HA/simvastatin electrospun nanofiber coating on biodegradable Mg alloy for orthopedic implant application
Published in JCT research (15-03-2019)“…Recently, magnesium (Mg) and its alloys have attracted more attention because of their biodegradability and fascinating mechanical properties in the medical…”
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Thermo-responsive-polymeric-gates of poly(N-isopropylacrylamide)/N-(hydroxymethyl)acrylamide coated magnetic nanoparticles as a synergistic approach to cancer therapy: Drug release and kinetics models of chemothermal magnetic nanoparticles
Published in Materials & design (01-10-2023)“…[Display omitted] •The SPNH/DOX nanoplatform presented controlled drug delivery with a chemo selective approach for chemotherapy.•The copolymer of…”
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De novo dual functional 3D scaffold using computational simulation with controlled drug release
Published in Journal of colloid and interface science (01-11-2022)“…Schematic of the dual effect of 3DPGHS scaffold on osteogenesis and angiogenesis, via the downstream regulation of ALP, RUNX2, COLA1, VEGF, and HIF1. [Display…”
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Development of conductive polymeric nanofiber patches for cardiac tissue engineering application
Published in Journal of applied polymer science (20-08-2022)“…Electrically conductive patches using biocompatible polymeric nanofibers have a beneficial effect on electroresponsive tissues such as the brain, heart, and…”
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Functional composite nanofibers loaded with β-TCP and SIM as a control drug delivery system
Published in Materials letters (01-04-2019)“…[Display omitted] •Incorporation proper amount of SIM and β-TCP particles into the FCN mat improved the biomineralization process.•Kopcha model used to study…”
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Marine plankton exoskeleton-derived honeycombed hydroxyapatite bone granule for bone tissue engineering
Published in Materials & design (01-12-2022)“…[Display omitted] •Bioinspired OceanBone-HAp possess a plethora of excellent bioactive properties.•Surface topography of OceanBone-HAp granules display unique…”
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pH-sensitive composite nanofibers of poly( -caprolactone) loaded with iron oxide nanoparticles/ammonium bicarbonate as a nanocarrier toward efficient doxorubicin release for postsurgical cancer treatment
Published in Materials advances (04-03-2024)“…The concurrent use of hyperthermia and chemotherapy has attracted considerable interest in the in situ treatment of cancer after surgical resection. In this…”
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Strategic design of a Mussel-inspired in situ reduced Ag/Au-Nanoparticle Coated Magnesium Alloy for enhanced viability, antibacterial property and decelerated corrosion rates for degradable implant Applications
Published in Scientific reports (15-01-2019)“…Magnesium (Mg) and its alloys have attracted much attention as a promising candidate for degradable implant applications however the rapid corrosion of…”
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Electroconductive Polythiophene Nanocomposite Fibrous Scaffolds for Enhanced Osteogenic Differentiation via Electrical Stimulation
Published in ACS biomaterials science & engineering (09-05-2022)“…Biophysical cues are key distinguishing characteristics that influence tissue development and regeneration, and significant efforts have been made to alter the…”
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Osteopromotive PDA-modified gold nanoparticles-incorporated bioinspired polycaprolactone-based nanofibers for bone cancer therapy and robust bone regeneration
Published in Materials today. Nano (01-03-2024)“…The limited efficacy of traditional therapies for bone cancer and related bone defects led to the instigation of new bifunctional therapies. In this work,…”
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