Search Results - "Rezeck Nunes, Priscila"
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Monocytes from preeclamptic women previously treated with silibinin attenuate oxidative stress in human endothelial cells
Published in Hypertension in pregnancy (03-04-2021)“…Objective: To investigate whether the supernatant from monocytes of preeclamptic and normotensive pregnant women, cultured in vitro with silibinin, can…”
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NLRP3 Activation and Its Relationship to Endothelial Dysfunction and Oxidative Stress: Implications for Preeclampsia and Pharmacological Interventions
Published in Cells (Basel, Switzerland) (21-10-2021)“…Preeclampsia (PE) is a specific syndrome of human pregnancy, being one of the main causes of maternal death. Persistent inflammation in the endothelium…”
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Silibinin Downregulates the NF-κB Pathway and NLRP1/NLRP3 Inflammasomes in Monocytes from Pregnant Women with Preeclampsia
Published in Molecules (Basel, Switzerland) (19-04-2019)“…Preeclampsia (PE) is a human pregnancy-specific syndrome with abnormal activation of cells from the innate immune system. The present study evaluated whether…”
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Endogenous and Uric Acid-Induced Activation of NLRP3 Inflammasome in Pregnant Women with Preeclampsia
Published in PloS one (08-06-2015)“…Preeclampsia (PE) is a specific syndrome of pregnancy, characterized by hypertension and proteinuria. This pathology is associated with hyperuricemia and…”
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EGCG, a Green Tea Compound, Increases NO Production and Has Antioxidant Action in a Static and Shear Stress In Vitro Model of Preeclampsia
Published in Antioxidants (01-01-2024)“…Preeclampsia (PE) is a gestational hypertensive disease characterized by endothelial dysfunction. Epigallocatechin-3-gallate (EGCG), the main compound in green…”
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6
Vascular contraction of umbilical arteries of pregnant women with preeclampsia
Published in Revista Brasileira de ginecologia e obstetrícia (01-01-2024)“…Potassium channels have an important role in the vascular adaptation during pregnancy and a reduction in the expression of adenosine triphosphate-sensitive…”
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A new look at the role of nitric oxide in preeclampsia: Protein S-nitrosylation
Published in Pregnancy hypertension (01-08-2022)“…•Protein S-nitrosylation status depends on the balance between S-nitrosylation and denitrosylation pathways.•S-nitrosylation can modulate NO availability with…”
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Markers of Endothelial Dysfunction Are Attenuated by Resveratrol in Preeclampsia
Published in Antioxidants (26-10-2022)“…Preeclampsia (PE) is characterized by great endothelial dysfunction, decreased nitric oxide (NO) bioavailability, and higher levels of arginase activity. In…”
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Potential role of uric acid to activate NLRP3 inflammasome triggering endothelial dysfunction in preeclampsia
Published in Clinical immunology communications (01-12-2022)“…Preeclampsia (PE) is a pregnancy-related disorder associated with increasing maternal death rates and affecting 2–8% of pregnant women worldwide. Arterial…”
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Inflammasomes in placental explants of women with preeclampsia cultured with monosodium urate may be modulated by vitamin D
Published in Hypertension in pregnancy (03-04-2022)“…Preeclampsia (PE) is an important syndrome of gestation characterized by placental and systemic inflammation. High plasma concentration of uric acid are…”
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Nebivolol Increases Nitric Oxide Synthase via β3 Adrenergic Receptor in Endothelial Cells Following Exposure to Plasma from Preeclamptic Patients
Published in Cells (Basel, Switzerland) (04-03-2022)“…Background: Low bioavailability of nitric oxide (NO) is related to the pathophysiology of preeclampsia (PE). In the present study, we investigated the effect…”
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Glibenclamide Increases Nitric Oxide Levels and Decreases Oxidative Stress in an In Vitro Model of Preeclampsia
Published in Antioxidants (01-08-2022)“…(1) Background: The bioavailability of nitric oxide (NO) and oxidative stress are important events related to the pathophysiology of preeclampsia (PE). In this…”
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Association between Adverse Maternal Clinical Outcomes and Imbalance of Cytokines and Angiogenic Factors in Preterm Preeclampsia
Published in Revista Brasileira de ginecologia e obstetrícia (01-09-2021)“…Preeclampsia (PE) is a pregnancy-specific syndrome characterized by abnormal levels of cytokines and angiogenic factors, playing a role in the disease…”
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69 Oxidative stress induces inflammatory response in placental explants: Immune and inflammatory mechanisms
Published in Pregnancy hypertension (01-07-2016)“…Oxidative stress arises from imbalance between generation of reactive oxygen species and anti-oxidant capacity of specific tissues. This alteration has been…”
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69 Oxidative stress induces inflammatory response in placental explants
Published in Pregnancy hypertension (01-07-2016)“…Introduction Oxidative stress arises from imbalance between generation of reactive oxygen species and anti-oxidant capacity of specific tissues. This…”
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Increase of autophagy marker p62 in the placenta from pregnant women with preeclampsia
Published in Human immunology (01-05-2022)“…Preeclampsia (PE) is a multisystemic disorder characterized by abnormal placentation. Autophagy is a lysosomal degradation pathway that removes protein…”
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Immunomodulatory effect of vitamin D on the STATs and transcription factors of CD4+ T cell subsets in pregnant women with preeclampsia
Published in Clinical immunology (Orlando, Fla.) (01-01-2022)“…This study evaluated the in vitro modulatory effect of vitamin D (VD) on T cells, by determining the expression of STATs and the transcription factors of each…”
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The interplay between extracellular NAMPT and inflammatory cytokines in preeclampsia
Published in Journal of reproductive immunology (01-06-2024)“…Preeclampsia (PE) is the major cause of maternal-fetal mortality and morbidity. Its pathophysiology is not elucidated, but there is evidence for the role of…”
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DAMPs are able to skew CD4+ T cell subsets and increase the inflammatory profile in pregnant women with preeclampsia
Published in Journal of reproductive immunology (01-02-2022)“…•Sterile inflammation is up-regulated by the presence of DAMPs in preeclampsia.•DAMPs stimulation can contribute to the activation of the adaptive immunity in…”
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Vitamin D modulates the transcription factors of T cell subsets to anti-inflammatory and regulatory profiles in preeclampsia
Published in International immunopharmacology (01-12-2021)“…[Display omitted] •Vitamin D downregulatesthe sterile inflammation in preeclampsia.•Pregnant women with preeclampsia have lower plasmatic levels of…”
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