Search Results - "Reynoso, Glennys V"

CXCR3 Chemokine Receptor Enables Local CD8+ T Cell Migration for the Destruction of Virus-Infected Cells by Hickman, Heather D., Reynoso, Glennys V., Ngudiankama, Barbara F., Cush, Stephanie S., Gibbs, James, Bennink, Jack R., Yewdell, Jonathan W.

“…CD8+ T cells play a critical role in limiting peripheral virus replication, yet how they locate virus-infected cells within tissues is unknown. Here, we have…”
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Enteric helminth coinfection enhances host susceptibility to neurotropic flaviviruses via a tuft cell-IL-4 receptor signaling axis by Desai, Pritesh, Janova, Hana, White, James P., Reynoso, Glennys V., Hickman, Heather D., Baldridge, Megan T., Urban, Joseph F., Stappenbeck, Thaddeus S., Thackray, Larissa B., Diamond, Michael S.

“…Although enteric helminth infections modulate immunity to mucosal pathogens, their effects on systemic microbes remain less established. Here, we observe…”
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MyD88-dependent influx of monocytes and neutrophils impairs lymph node B cell responses to chikungunya virus infection via Irf5, Nos2 and Nox2 by McCarthy, Mary K, Reynoso, Glennys V, Winkler, Emma S, Mack, Matthias, Diamond, Michael S, Hickman, Heather D, Morrison, Thomas E

“…Humoral immune responses initiate in the lymph node draining the site of viral infection (dLN). Some viruses subvert LN B cell activation; however, our…”
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Anatomically Restricted Synergistic Antiviral Activities of Innate and Adaptive Immune Cells in the Skin by Hickman, Heather D., Reynoso, Glennys V., Ngudiankama, Barbara F., Rubin, Erica J., Magadán, Javier G., Cush, Stephanie S., Gibbs, James, Molon, Barbara, Bronte, Vincenzo, Bennink, Jack R., Yewdell, Jonathan W.

“…Despite extensive ex vivo investigation, the spatiotemporal organization of immune cells interacting with virus-infected cells in tissues remains uncertain. To…”
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Zika virus spreads through infection of lymph node-resident macrophages by Reynoso, Glennys V., Gordon, David N., Kalia, Anurag, Aguilar, Cynthia C., Malo, Courtney S., Aleshnick, Maya, Dowd, Kimberly A., Cherry, Christian R., Shannon, John P., Vrba, Sophia M., Holmes, Autumn C., Alippe, Yael, Maciejewski, Sonia, Asano, Kenichi, Diamond, Michael S., Pierson, Theodore C., Hickman, Heather D.

“…To disseminate through the body, Zika virus (ZIKV) is thought to exploit the mobility of myeloid cells, in particular monocytes and dendritic cells. However,…”
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Intranasal Live Influenza Vaccine Priming Elicits Localized B Cell Responses in Mediastinal Lymph Nodes by Jegaskanda, Sinthujan, Mason, Rosemarie D, Andrews, Sarah F, Wheatley, Adam K, Zhang, Ruijun, Reynoso, Glennys V, Ambrozak, David R, Santos, Celia P, Luke, Catherine J, Matsuoka, Yumiko, Brenchley, Jason M, Hickman, Heather D, Talaat, Kawsar R, Permar, Sallie R, Liao, Hua-Xin, Yewdell, Jonathan W, Koup, Richard A, Roederer, Mario, McDermott, Adrian B, Subbarao, Kanta

“…Pandemic live attenuated influenza vaccines (pLAIV) prime subjects for a robust neutralizing antibody response upon subsequent administration of a pandemic…”
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Locally Produced IL-10 Limits Cutaneous Vaccinia Virus Spread by Cush, Stephanie S, Reynoso, Glennys V, Kamenyeva, Olena, Bennink, Jack R, Yewdell, Jonathan W, Hickman, Heather D

“…Skin infection with the poxvirus vaccinia (VV) elicits a powerful, inflammatory cellular response that clears virus infection in a coordinated, spatially…”
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Multifaceted roles for STAT3 in gammaherpesvirus latency revealed through in vivo B cell knockout models by Hogan, Chad H, Owens, Shana M, Reynoso, Glennys V, Liao, Yifei, Meyer, Thomas J, Zelazowska, Monika A, Liu, Bin, Li, Xiaofan, Grosskopf, Anna K, Khairallah, Camille, Kirillov, Varvara, Reich, Nancy C, Sheridan, Brian S, McBride, Kevin M, Gewurz, Benjamin E, Hickman, Heather D, Forrest, J Craig, Krug, Laurie T

“…Cancers associated with the oncogenic gammaherpesviruses, Epstein-Barr virus and Kaposi sarcoma herpesvirus, are notable for their constitutive activation of…”
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The ectromelia virus virulence factor C15 facilitates early viral spread by inhibiting NK cell contact by Peauroi, Elise M., Carro, Stephen D., Pei, Luxin, Reynoso, Glennys V., Hickman, Heather D., Eisenlohr, Laurence C.

“…The success of poxviruses as pathogens depends on their antagonism of host responses by multiple immunomodulatory proteins. The largest of these expressed by…”
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An Agonistic Anti-CD137 Antibody Disrupts Lymphoid Follicle Structure and T-Cell-Dependent Antibody Responses by Hong, Jun P., Reynoso, Glennys V., Andhey, Prabhakar S., Swain, Amanda, Turner, Jackson S., Boon, Adrianus C.M., Krammer, Florian, Ellebedy, Ali H., Zanini, Fabio, Artyomov, Maxim, Hickman, Heather D., Diamond, Michael S.

“…CD137 is a costimulatory receptor expressed on natural killer cells, T cells, and subsets of dendritic cells. An agonistic monoclonal antibody (mAb) against…”
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Intravenous nanoparticle vaccination generates stem-like TCF1+ neoantigen-specific CD8+ T cells by Baharom, Faezzah, Ramirez-Valdez, Ramiro A., Tobin, Kennedy K. S., Yamane, Hidehiro, Dutertre, Charles-Antoine, Khalilnezhad, Ahad, Reynoso, Glennys V., Coble, Vincent L., Lynn, Geoffrey M., Mulè, Matthew P., Martins, Andrew J., Finnigan, John P., Zhang, Xiao Meng, Hamerman, Jessica A., Bhardwaj, Nina, Tsang, John S., Hickman, Heather D., Ginhoux, Florent, Ishizuka, Andrew S., Seder, Robert A.

“…Personalized cancer vaccines are a promising approach for inducing T cell immunity to tumor neoantigens. Using a self-assembling nanoparticle vaccine that…”
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Lymph node conduits transport virions for rapid T cell activation by Reynoso, Glennys V., Weisberg, Andrea S., Shannon, John P., McManus, Daniel T., Shores, Lucas, Americo, Jeffrey L., Stan, Radu V., Yewdell, Jonathan W., Hickman, Heather D.

“…Despite intense interest in antiviral T cell priming, the routes by which virions move in lymph nodes (LNs) are imperfectly understood. Current models fail to…”
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Group 1 innate lymphoid-cell-derived interferon-γ maintains anti-viral vigilance in the mucosal epithelium by Shannon, John P., Vrba, Sophia M., Reynoso, Glennys V., Wynne-Jones, Erica, Kamenyeva, Olena, Malo, Courtney S., Cherry, Christian R., McManus, Daniel T., Hickman, Heather D.

“…The oropharyngeal mucosa serves as a perpetual pathogen entry point and a critical site for viral replication and spread. Here, we demonstrate that type 1…”
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Intravital Imaging of Vaccinia Virus-Infected Mice by Shannon, John P, Kamenyeva, Olena, Reynoso, Glennys V, Hickman, Heather D

“…Intravital multiphoton microscopy (MPM) allows the direct visualization of viral infections in real time as they occur in living animals. Here we describe the…”
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MARCO+ lymphatic endothelial cells sequester arthritogenic alphaviruses to limit viremia and viral dissemination by Carpentier, Kathryn S, Sheridan, Ryan M, Lucas, Cormac J, Davenport, Bennett J, Li, Frances S, Lucas, Erin D, McCarthy, Mary K, Reynoso, Glennys V, May, Nicholas A, Tamburini, Beth A J, Hesselberth, Jay R, Hickman, Heather D, Morrison, Thomas E

“…Viremia in the vertebrate host is a major determinant of arboviral reservoir competency, transmission efficiency, and disease severity. However, immune…”
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Vaccinia virus hijacks EGFR signalling to enhance virus spread through rapid and directed infected cell motility by Beerli, Corina, Yakimovich, Artur, Kilcher, Samuel, Reynoso, Glennys V., Fläschner, Gotthold, Müller, Daniel J., Hickman, Heather D., Mercer, Jason

“…Cell motility is essential for viral dissemination 1 . Vaccinia virus (VACV), a close relative of smallpox virus, is thought to exploit cell motility as a…”
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Influenza A Virus Negative Strand RNA Is Translated for CD8 + T Cell Immunosurveillance by Hickman, Heather D, Mays, Jacqueline W, Gibbs, James, Kosik, Ivan, Magadán, Javier G, Takeda, Kazuyo, Das, Suman, Reynoso, Glennys V, Ngudiankama, Barbara F, Wei, JiaJie, Shannon, John P, McManus, Daniel, Yewdell, Jonathan W

“…Probing the limits of CD8 T cell immunosurveillance, we inserted the SIINFEKL peptide into influenza A virus (IAV)-negative strand gene segments. Although IAV…”
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Defining Viral Defective Ribosomal Products: Standard and Alternative Translation Initiation Events Generate a Common Peptide from Influenza A Virus M2 and M1 mRNAs by Yang, Ning, Gibbs, James S, Hickman, Heather D, Reynoso, Glennys V, Ghosh, Arun K, Bennink, Jack R, Yewdell, Jonathan W

“…Influenza A virus gene segment 7 encodes two proteins: the M1 protein translated from unspliced mRNA and the M2 protein produced by mRNA splicing and largely…”
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Growth and Purification of Vaccinia Virus Stocks for MPM Imaging by Reynoso, Glennys V, Shannon, John P, Americo, Jeffrey L, Gibbs, James, Hickman, Heather D

“…This chapter provides methods for the propagation, purification, and titration of vaccinia virus (VACV) and the highly attenuated strain-modified vaccinia…”
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Chemokines control naive CD8+ T cell selection of optimal lymph node antigen presenting cells by Hickman, Heather D, Li, Lily, Reynoso, Glennys V, Rubin, Erica J, Skon, Cara N, Mays, Jacqueline W, Gibbs, James, Schwartz, Owen, Bennink, Jack R, Yewdell, Jonathan W

“…Naive antiviral CD8(+) T cells are activated in the draining LN (DLN) by dendritic cells (DCs) presenting viral antigens. However, many viruses infect LN…”
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