Search Results - "Reynolds, Simone L."
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Pseudoproteases: mechanisms and function
Published in Biochemical journal (15-05-2015)“…Catalytically inactive enzymes (also known as pseudoproteases, protease homologues or paralogues, non-peptidase homologues, non-enzymes and pseudoenzymes) have…”
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A unique group of scabies mite pseudoproteases promotes cutaneous blood coagulation and delays plasmin-induced fibrinolysis
Published in PLoS neglected tropical diseases (06-01-2021)“…Scabies, a highly contagious skin disease affecting more than 200 million people worldwide at any time, is caused by the parasitic mite Sarcoptes scabiei. In…”
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High-quality nuclear genome for Sarcoptes scabiei-A critical resource for a neglected parasite
Published in PLoS neglected tropical diseases (01-10-2020)“…The parasitic mite Sarcoptes scabiei is an economically highly significant parasite of the skin of humans and animals worldwide. In humans, this mite causes a…”
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Scabies mite inactive serine proteases are potent inhibitors of the human complement lectin pathway
Published in PLoS neglected tropical diseases (01-05-2014)“…Scabies is an infectious skin disease caused by the mite Sarcoptes scabiei and has been classified as one of the six most prevalent epidermal parasitic skin…”
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Complement inhibitors from scabies mites promote streptococcal growth--a novel mechanism in infected epidermis?
Published in PLoS neglected tropical diseases (01-07-2012)“…Scabies is highly prevalent in socially disadvantaged communities such as indigenous populations and in developing countries. Generalized itching causes…”
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Gene silencing by RNA interference in Sarcoptes scabiei: a molecular tool to identify novel therapeutic targets
Published in Parasites & vectors (10-06-2017)“…Scabies is one of the most common and widespread parasitic skin infections globally, affecting a large range of mammals including humans, yet the molecular…”
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Phylogenetic relationships, stage-specific expression and localisation of a unique family of inactive cysteine proteases in Sarcoptes scabiei
Published in Parasites & vectors (16-05-2018)“…Scabies is worldwide one of the most common, yet neglected, parasitic skin infections, affecting a wide range of mammals including humans. Limited treatment…”
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Novel scabies mite serpins inhibit the three pathways of the human complement system
Published in PloS one (11-07-2012)“…Scabies is a parasitic infestation of the skin by the mite Sarcoptes scabiei that causes significant morbidity worldwide, in particular within socially…”
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Intestinal proteases of free-living and parasitic astigmatid mites
Published in Cell and tissue research (01-02-2013)“…Among arthropod pests, mites are responsible for considerable damage to crops, humans and other animals. However, detailed physiological data on these…”
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Scabies Mite Inactive Serine Proteases Are Potent Inhibitors of the Human Complement Lectin Pathway: e2872
Published in PLoS neglected tropical diseases (01-05-2014)“…Scabies is an infectious skin disease caused by the mite Sarcoptes scabiei and has been classified as one of the six most prevalent epidermal parasitic skin…”
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