Search Results - "Reynolds, M. H."

Zebrafish: an emerging technology for in vivo pharmacological assessment to identify potential safety liabilities in early drug discovery by Barros, T P, Alderton, W K, Reynolds, H M, Roach, A G, Berghmans, S

“…The zebrafish is a well‐established model organism used in developmental biology. In the last decade, this technology has been extended to the generation of…”
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Voxel-level biological optimisation of prostate IMRT using patient-specific tumour location and clonogen density derived from mpMRI by Her, E J, Haworth, A, Reynolds, H M, Sun, Y, Kennedy, A, Panettieri, V, Bangert, M, Williams, S, Ebert, M A

“…This study aimed to develop a framework for optimising prostate intensity-modulated radiotherapy (IMRT) based on patient-specific tumour biology, derived from…”
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Relationship between femoral head size and distance to lesser trochanter by Sproul, Robert C, Reynolds, H M, Lotz, Jeffrey C, Ries, Michael D

“…Hemiarthroplasty of the hip is a common treatment for displaced fractures of the femoral neck. However, accurate restoration of leg length may be difficult to…”
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Standard versus hypofractionated intensity-modulated radiotherapy for prostate cancer: assessing the impact on dose modulation and normal tissue effects when using patient-specific cancer biology by Her, E J, Ebert, M A, Kennedy, A, Reynolds, H M, Sun, Y, Williams, S, Haworth, A

“…Hypofractionation of prostate cancer radiotherapy achieves tumour control at lower total radiation doses, however, increased rectal and bladder toxicities have…”
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Microsatellite variation and rare alleles in a bottlenecked Hawaiian Islands endemic: implications for reintroductions by Reynolds, MH, Pearce, JM, Lavretsky, P, Seixas, PP, Courtot, KN

“…Conservation of genetic biodiversity in endangered wildlife populations is an important challenge to address since the loss of alleles and genetic drift may…”
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Development of a registration framework to validate MRI with histology for prostate focal therapy by Reynolds, H. M., Williams, S., Zhang, A., Chakravorty, R., Rawlinson, D., Ong, C. S., Esteva, M., Mitchell, C., Parameswaran, B., Finnegan, M., Liney, G., Haworth, A.

“…Purpose: Focal therapy has been proposed as an alternative method to whole‐gland treatment for prostate cancer when aiming to reduce treatment side effects…”
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Influence of space use on fitness and the reintroduction success of the Laysan teal by Reynolds, M. H., Hatfield, J. S., Laniawe, L. P., Vekasy, M. S., Klavitter, J. L., Berkowitz, P., Crampton, L. H., Walters, J. R.

“…Translocation is an important tool for wildlife conservation and biodiversity restoration, but an inefficient one because of the unpredictability of success…”
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Viscosupplementation: a new treatment option for osteoarthritis by Geier, Kathleen A, Keeperman, Jacob B, Sproul, Robert C, Roth, Kevin, Reynolds, H M

“…Osteoarthritis (OA), a degenerative joint disease affecting articular cartilage and synovial joint fluid, is the most common of the rheumatic diseases. OA is a…”
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Population Structure and Survival of Palila by Lindsey, G. D., Fancy, S. G., Reynolds, M. H., Pratt, T. K., Wilson, K. A., Banko, P. C., Jacobi, J. D.

“…Annual survival, age, and sex ratios of the endangered Palila (Loxioides bailleui) on Mauna Kea, Hawaii, were determined from multiple captures and resightings…”
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A Role for dNTP Binding of Human Immunodeficiency Virus Type 1 Reverse Transcriptase in Viral Mutagenesis by Weiss, Kellie K, Chen, Renxiang, Skasko, Mark, Reynolds, Holly M, Lee, Kwi, Bambara, Robert A, Mansky, Louis M, Kim, Baek

“…HIV-1 reverse transcriptase (RT) is a highly error prone DNA polymerase. We assessed whether the ability of RT to bind nucleotide substrates affects viral…”
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Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases by Operario, Darwin J., Reynolds, Holly M., Kim, Baek

“…In this study, we present enzymatic differences found between recombinant RTs derived from feline leukemia virus and feline immunodeficiency virus. Firstly,…”
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Inhibition of the immune response to experimental fresh osteoarticular allografts by Rodrigo, J J, Schnaser, A M, Reynolds, Jr, H M, Biggart, 3rd, J M, Leathers, M W, Chism, S E, Thorson, E, Grotz, T, Yang, Q M

“…The immune response to osteoarticular allografts is capable of destroying the cartilage--a tissue that has antigens on its cells identical to those on the bone…”
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Perioperative care for patients with sickle cell who are undergoing total hip replacement as treatment for osteonecrosis by Hammer, Marjorie, Geier, Kathleen A, Aksoy, Sara, Reynolds, H M

“…Sickle cell disease, which is characterized by chronic hemolytic anemia, is prevalent in the United States. In addition to the profound multisystem effects of…”
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Habitat Use and Home Range of the Laysan Teal on Laysan Island, Hawaii by Reynolds, Michelle H

“…The 24-hour habitat use and home range of the Laysan Teal (Anas laysanensis), an endemic dabbling duck in Hawaii, was studied using radio telemetry during…”
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Quantifying passive resistance to motion in the straight-leg-raising test on asymptomatic subjects by Reynolds, H M, Beal, M C, Hallgren, R C

“…The clinician needs an objective way to measure limb motion in the straight-leg-raising test. A biomechanical algorithm was used to quantify resistance to…”
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Spinal Curvature of Young Adult Females by REYNOLDS, HERBERT M., RECHTIEN, JAMES J., MARSHALL, GRAYSON W., MARSHALL, SALLY

“…Mid-sagittal curvature of the spinal column from C7 to the posterior superior iliac spines has been measured directly on sixteen healthy, volunteer,…”
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Tumor growth in experimental animals: nutritional manipulation and chemotherapeutic response in the rat by Daly, J M, Reynolds, H M, Rowlands, B J, Dudrick, S J, Copeland, 3rd, E M

“…The effects of nutritional manipulation on host body weight dynamics, tumor growth patterns and host-tumor responses to chemotherapy were studied in…”
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Is statistical power to detect trends a good assessment of population monitoring? by Seavy, Nathaniel E., Reynolds, Michelle H.

“…The ability to detect trends in population abundance is of obvious interest to wildlife managers. In recent years, the probability of detecting defined…”
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Anatomical frames of reference and biomechanics by Reynolds, H M, Hubbard, R P

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Response of Six Species of Hawaiian Forest Birds to a 1991-1992 El Nino Drought by Lindsey, Gerald D., Pratt, Thane K., Michelle H. Reynolds, Jacobi, James D.

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