Search Results - "Reynolds, Holly M"

Macrophage Tropism of HIV-1 Depends on Efficient Cellular dNTP Utilization by Reverse Transcriptase by Diamond, Tracy L., Roshal, Mikhail, Jamburuthugoda, Varuni K., Reynolds, Holly M., Merriam, Aaron R., Lee, Kwi Y., Balakrishnan, Mini, Bambara, Robert A., Planelles, Vicente, Dewhurst, Stephen, Kim, Baek

“…Retroviruses utilize cellular dNTPs to perform proviral DNA synthesis in infected host cells. Unlike oncoretroviruses, which replicate in dividing cells,…”
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HIV-1 Tat-induced microgliosis and synaptic damage via interactions between peripheral and central myeloid cells by Lu, Shao-Ming, Tremblay, Marie-Ève, King, Irah L, Qi, Jin, Reynolds, Holly M, Marker, Daniel F, Varrone, John J P, Majewska, Ania K, Dewhurst, Stephen, Gelbard, Harris A

“…Despite the ability of combination antiretroviral treatment (cART) to reduce viral burden to nearly undetectable levels in cerebrospinal fluid and serum, HIV-1…”
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HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization by Norman, John P, Perry, Seth W, Reynolds, Holly M, Kiebala, Michelle, De Mesy Bentley, Karen L, Trejo, Margarita, Volsky, David J, Maggirwar, Sanjay B, Dewhurst, Stephen, Masliah, Eliezer, Gelbard, Harris A

“…Neurologic disease caused by human immunodeficiency virus type 1 (HIV-1) is ultimately refractory to highly active antiretroviral therapy (HAART) because of…”
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Mechanistic Differences in RNA-dependent DNA Polymerization and Fidelity between Murine Leukemia Virus and HIV-1 Reverse Transcriptases by Skasko, Mark, Weiss, Kellie K., Reynolds, Holly M., Jamburuthugoda, Varuni, Lee, Kwi, Kim, Baek

“…We compared the mechanistic and kinetic properties of murine leukemia virus (MuLV) and human immunodeficiency virus type 1 (HIV-1) reverse transcriptases (RTs)…”
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A Role for dNTP Binding of Human Immunodeficiency Virus Type 1 Reverse Transcriptase in Viral Mutagenesis by Weiss, Kellie K, Chen, Renxiang, Skasko, Mark, Reynolds, Holly M, Lee, Kwi, Bambara, Robert A, Mansky, Louis M, Kim, Baek

“…HIV-1 reverse transcriptase (RT) is a highly error prone DNA polymerase. We assessed whether the ability of RT to bind nucleotide substrates affects viral…”
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Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases by Operario, Darwin J., Reynolds, Holly M., Kim, Baek

“…In this study, we present enzymatic differences found between recombinant RTs derived from feline leukemia virus and feline immunodeficiency virus. Firstly,…”
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Macrophage tropism of HIV-1 depends upon efficient cellular dNTP utilization by reverse transcriptase by Diamond, Tracy L., Roshal, Mikhail, Jamburuthugoda, Varuni K., Reynolds, Holly M., Merriam, Aaron R., Lee, Kwi Y., Balakrishnan, Mini, Bambara, Robert A., Planelles, Vicente, Dewhurst, Stephen, Kim, Baek

“…Retroviruses utilize cellular dNTPs to perform proviral DNA synthesis in infected host cells. Unlike oncoretroviruses, which replicate only in dividing cells,…”
Get full text