Search Results - "Reynolds, Chandra"

Comparing Within- and Between-Family Polygenic Score Prediction by Selzam, Saskia, Ritchie, Stuart J., Pingault, Jean-Baptiste, Reynolds, Chandra A., O’Reilly, Paul F., Plomin, Robert

“…Polygenic scores are a popular tool for prediction of complex traits. However, prediction estimates in samples of unrelated participants can include effects of…”
Get full text

Differences Between Women and Men in Incidence Rates of Dementia and Alzheimer's Disease by Beam, Christopher R, Kaneshiro, Cody, Jang, Jung Yun, Reynolds, Chandra A, Pedersen, Nancy L, Gatz, Margaret

“…In the following brief report, we examined gender differences in incidence rates of any dementia, Alzheimer's disease (AD) alone, and non-Alzheimer's dementia…”
Get more information

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses by Brumpton, Ben, Sanderson, Eleanor, Heilbron, Karl, Hartwig, Fernando Pires, Harrison, Sean, Vie, Gunnhild Åberge, Cho, Yoonsu, Howe, Laura D., Hughes, Amanda, Boomsma, Dorret I., Havdahl, Alexandra, Hopper, John, Neale, Michael, Nivard, Michel G., Pedersen, Nancy L., Reynolds, Chandra A., Tucker-Drob, Elliot M., Grotzinger, Andrew, Howe, Laurence, Morris, Tim, Li, Shuai, Auton, Adam, Windmeijer, Frank, Chen, Wei-Min, Bjørngaard, Johan Håkon, Hveem, Kristian, Willer, Cristen, Evans, David M., Kaprio, Jaakko, Davey Smith, George, Åsvold, Bjørn Olav, Hemani, Gibran, Davies, Neil M.

“…Estimates from Mendelian randomization studies of unrelated individuals can be biased due to uncontrolled confounding from familial effects. Here we describe…”
Get full text

A twin-driven analysis on early aging biomarkers and associations with sitting-time and physical activity by Bruellman, Ryan, Pahlen, Shandell, Ellingson, Jarrod M, Corley, Robin P, Wadsworth, Sally J, Reynolds, Chandra A

“…Current physical activity guidelines may be insufficient to address health consequences in a world increasing in sedentary behavior. Physical activity is a key…”
Get full text

Longitudinal trajectories, correlations and mortality associations of nine biological ages across 20-years follow-up by Li, Xia, Ploner, Alexander, Wang, Yunzhang, Magnusson, Patrik Ke, Reynolds, Chandra, Finkel, Deborah, Pedersen, Nancy L, Jylhävä, Juulia, Hägg, Sara

“…Biological age measurements (BAs) assess aging-related physiological change and predict health risks among individuals of the same chronological age (CA)…”
Get full text

Influence of young adult cognitive ability and additional education on later-life cognition by Kremen, William S., Beck, Asad, Elman, Jeremy A., Gustavson, Daniel E., Reynolds, Chandra A., Tu, Xin M., Sanderson-Cimino, Mark E., Panizzon, Matthew S., Vuoksimaa, Eero, Toomey, Rosemary, Fennema-Notestine, Christine, Hagler, Donald J., Fang, Bin, Dale, Anders M., Lyons, Michael J., Franz, Carol E.

“…How and when education improves cognitive capacity is an issue of profound societal importance. Education and later-life education-related factors, such as…”
Get full text

Personality and Health, Subjective Well-Being, and Longevity by Friedman, Howard S., Kern, Margaret L., Reynolds, Chandra A.

“…ABSTRACT Personality traits can be employed to guide understanding of trajectories to health and longevity, but long‐term longitudinal study and multifaceted…”
Get full text

An examination of early socioeconomic status and neighborhood disadvantage as independent predictors of antisocial behavior: A longitudinal adoption study by Gresko, Shelley A, Hink, Laura K, Corley, Robin P, Reynolds, Chandra A, Muñoz, Elizabeth, Rhee, Soo Hyun

“…The present study examined early socioeconomic status (SES) and neighborhood disadvantage (ND) as independent predictors of antisocial behavior (ASB) and…”
Get full text

Perceptions of Romantic Partners' Responsiveness During a Period of Stressful Uncertainty by Dooley, Michael K, Sweeny, Kate, Howell, Jennifer L, Reynolds, Chandra A

“…Whether awaiting biopsy results, a grade on a midterm, or a decision from a journal editor, people feel distressed as they wait for uncertain news. In the…”
Get full text

Use of an Alzheimer’s disease polygenic risk score to identify mild cognitive impairment in adults in their 50s by Logue, Mark W., Panizzon, Matthew S., Elman, Jeremy A., Gillespie, Nathan A., Hatton, Sean N., Gustavson, Daniel E., Andreassen, Ole A., Dale, Anders M., Franz, Carol E., Lyons, Michael J., Neale, Michael C., Reynolds, Chandra A., Tu, Xin, Kremen, William S.

“…Early identification of younger, non-demented adults at elevated risk for Alzheimer’s disease (AD) is crucial because the pathological process begins decades…”
Get full text

Frailty and Processing Speed Performance at the Cusp of Midlife in CATSLife by Luna, Maria G, Pahlen, Shandell, Corley, Robin P, Wadsworth, Sally J, Reynolds, Chandra A

“…Abstract Objectives Frailty is not an end state of aging, but rather represents physiological vulnerability across multiple systems that unfolds across…”
Get full text

Genetic Associations Between Executive Functions and Intelligence: A Combined Twin and Adoption Study by Gustavson, Daniel E., Reynolds, Chandra A., Corley, Robin P., Wadsworth, Sally J., Hewitt, John K., Friedman, Naomi P.

“…Much debate has concerned the separability of executive function abilities and intelligence, with some evidence that the 2 constructs are genetically…”
Get full text

Pubertal timing in adolescence and adulthood: Relations among contemporaneous and retrospective measures by Chaku, Natasha, Berenbaum, Sheri A, Qian, Yiming, Corley, Robin P, Wadsworth, Sally J, Reynolds, Chandra A, Beltz, Adriene M

“…Pubertal development has short- and long-term effects on psychological adjustment. Many studies of long-term effects rely on retrospective measurement of…”
Get full text

Age-dependent effects of body mass index across the adult life span on the risk of dementia: a cohort study with a genetic approach by Karlsson, Ida K, Lehto, Kelli, Gatz, Margaret, Reynolds, Chandra A, Dahl Aslan, Anna K

“…While a high body mass index (BMI) in midlife is associated with higher risk of dementia, high BMI in late-life may be associated with lower risk. This study…”
Get full text

Grip Strength and Cognitive Abilities: Associations in Old Age by Sternäng, Ola, Reynolds, Chandra A, Finkel, Deborah, Ernsth-Bravell, Marie, Pedersen, Nancy L, Dahl Aslan, Anna K

“…Both physical functioning and cognitive abilities are important for well-being, not least in old age. Grip strength is often considered an indicator of general…”
Get full text

The dynamic association between body mass index and cognition from midlife through late-life, and the effect of sex and genetic influences by Karlsson, Ida K., Gatz, Margaret, Arpawong, Thalida Em, Dahl Aslan, Anna K., Reynolds, Chandra A.

“…Body mass index (BMI) is associated with cognitive abilities, but the nature of the relationship remains largely unexplored. We aimed to investigate the…”
Get full text

Integrating Verbal Fluency With Executive Functions: Evidence From Twin Studies in Adolescence and Middle Age by Gustavson, Daniel E., Panizzon, Matthew S., Franz, Carol E., Reynolds, Chandra A., Corley, Robin P., Hewitt, John K., Lyons, Michael J., Kremen, William S., Friedman, Naomi P.

“…The relationship of verbal fluency to executive functions (EFs) remains somewhat unclear. Verbal fluency is sometimes considered an EF ability, but is not…”
Get full text

Exploring the Causal Pathway From Telomere Length to Coronary Heart Disease: A Network Mendelian Randomization Study by Zhan, Yiqiang, Karlsson, Ida K, Karlsson, Robert, Tillander, Annika, Reynolds, Chandra A, Pedersen, Nancy L, Hägg, Sara

“…Observational studies have found shorter leukocyte telomere length (TL) to be a risk factor for coronary heart disease (CHD), and recently the association was…”
Get full text

Telomere Length Shortening and Alzheimer Disease--A Mendelian Randomization Study by Zhan, Yiqiang, Song, Ci, Karlsson, Robert, Tillander, Annika, Reynolds, Chandra A, Pedersen, Nancy L, Hägg, Sara

Get more information

A Meta-analysis of Heritability of Cognitive Aging: Minding the “Missing Heritability” Gap by Reynolds, Chandra A., Finkel, Deborah

“…The etiologies underlying variation in adult cognitive performance and cognitive aging have enjoyed much attention in the literature, but much of that…”
Get full text