Search Results - "Reynders, Martin"

Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death by Borowiak, Malgorzata, Nahaboo, Wallis, Reynders, Martin, Nekolla, Katharina, Jalinot, Pierre, Hasserodt, Jens, Rehberg, Markus, Delattre, Marie, Zahler, Stefan, Vollmar, Angelika, Trauner, Dirk, Thorn-Seshold, Oliver

“…Small molecules that interfere with microtubule dynamics, such as Taxol and the Vinca alkaloids, are widely used in cell biology research and as clinical…”
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PHOTACs enable optical control of protein degradation by Reynders, Martin, Matsuura, Bryan S, Bérouti, Marleen, Simoneschi, Daniele, Marzio, Antonio, Pagano, Michele, Trauner, Dirk

“…PROTACs (PROteolysis TArgeting Chimeras) are bifunctional molecules that target proteins for ubiquitylation by an E3 ligase complex and subsequent degradation…”
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PHOTACs Enable Optical Control of Protein Degradation by Reynders, Martin, Trauner, Dirk

“…Proteolysis Targeting Chimeras (PROTACs) are a promising technology to degrade specific target proteins. As bifunctional small molecules, PROTACs induce the…”
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Controlling the Covalent Reactivity of a Kinase Inhibitor with Light by Reynders, Martin, Chaikuad, Apirat, Berger, Benedict‐Tilman, Bauer, Katharina, Koch, Pierre, Laufer, Stefan, Knapp, Stefan, Trauner, Dirk

“…Covalent kinase inhibitors account for some of the most successful drugs that have recently entered the clinic and many others are in preclinical development…”
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Oxidative Approach Enables Efficient Access to Cyclic Azobenzenes by Maier, Martin S, Hüll, Katharina, Reynders, Martin, Matsuura, Bryan S, Leippe, Philipp, Ko, Tongil, Schäffer, Lukas, Trauner, Dirk

“…Azobenzenes are versatile photoswitches that have found widespread use in a variety of fields, ranging from photopharmacology to the material sciences. In…”
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A High‐Quality Photoswitchable Probe that Selectively and Potently Regulates the Transcription Factor RORγ by Reynders, Martin, Willems, Sabine, Marschner, Julian A., Wein, Thomas, Merk, Daniel, Thorn‐Seshold, Oliver

“…Retinoic acid receptor‐related orphan receptor γ (RORγ) is a nuclear hormone receptor with multiple biological functions in circadian clock regulation,…”
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Diagnostic thresholds for free light chains in multiple myeloma depend on the assay used by Bossuyt, Xavier, Delforge, Michel, Reynders, Martin, Dillaerts, Doreen, Sprangers, Ben, Fostier, Karel, Poesen, Koen, Vercammen, Martine

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The need to improve registration practices in the context of space traffic management by Masson-Zwaan, Tanja, Martinez, Peter, Letizia, Francesca, Melograna, Catrina, Reynders, Martin, Rovetto, Robert, Skinner, Mark A., Stanciu-Manolescu, Marius, Strah, Maruska, Volynskaya, Olga, Wang, Guoyu

“…This paper examines the legal basis and framework for the United Nations registration process for space objects. UN registration processes are compared against…”
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Eine hochwertige photoschaltbare Sonde, die selektiv und wirksam den Transkriptionsfaktor RORγ moduliert by Reynders, Martin, Willems, Sabine, Marschner, Julian A., Wein, Thomas, Merk, Daniel, Thorn‐Seshold, Oliver

“…Der Retinsäure‐Rezeptor‐verwandte Waisen‐Rezeptor γ (RORγ) ist ein nuklearer Hormonrezeptor mit vielfältigen biologischen Funktionen in der Regulation der…”
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Photoactivated Protein Degrader for Optical Control of Synaptic Function by Ko, Tongil, Jou, Claudia, Grau-Perales, Alejandro B., Reynders, Martin, Fenton, André A., Trauner, Dirk

“…Hundreds of proteins determine the function of synapses, and synapses define the neuronal circuits that subserve myriad brain, cognitive, and behavioral…”
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A photo-SAR study of photoswitchable azobenzene tubulin-inhibiting antimitotics identifying a general method for near-quantitative photocontrol by Reynders, Martin, Garścia, Małgorzata, Müller-Deku, Adrian, Wranik, Maximilian, Krauskopf, Kristina, de la Osa de la Rosa, Luis, Schaffer, Konstantin, Jötten, Anna, Rode, Alexander, Stierle, Valentin, Kraus, Yvonne, Baumgartner, Benedikt, Ali, Ahmed, Bubeneck, Andrei, Seal, Trina, Steinmetz, Michel O, Paulitschke, Philipp, Thorn-Seshold, Oliver

“…Azobenzene analogues of the tubulin polymerisation inhibitor combretastatin A4 (PSTs) were previously developed to optically control microtubule dynamics in…”
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Antigen excess detection by automated assays for free light chains by Bossuyt, Xavier, Delforge, Michel, Reynders, Martin, Dillaerts, Doreen, Sprangers, Ben, Fostier, Karel, Poesen, Koen, Vercammen, Martine

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(2-Fluoro-2,2-dinitroethyl)-2,2,2-trinitroethylnitramine: A Possible High-Energy Dense Oxidizer by Klapötke, Thomas M., Krumm, Burkhard, Rest, Sebastian F., Reynders, Martin, Scharf, Regina

“…The fluorine‐containing polynitro energetic molecule (2‐fluoro‐2,2‐dinitroethyl)‐2,2,2‐trinitroethylnitramine and the corresponding precursors were synthesized…”
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Diagnostic thresholds for free light chains in multiple myeloma depend on the assay used by Bossuyt, X, Delforge, M, Reynders, M, Dillaerts, D, Sprangers, B, Fostier, K, Poesen, K, Vercammen, M

“…Leukemia accepted article preview online, 20 November 2017. doi:10.1038/leu.2017.335…”
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Controlling the Covalent Reactivity of a Kinase Inhibitor with Light by Reynders, Martin, Chaikuad, Apirat, Berger, Benedict‐Tilman, Bauer, Katharina, Koch, Pierre, Laufer, Stefan, Knapp, Stefan, Trauner, Dirk

“…Covalent kinase inhibitors account for some of the most successful drugs that have recently entered the clinic and many others are in preclinical development…”
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Multiply Nitrated High-Energy Dense Oxidizers Derived from the Simple Amino Acid Glycine by Baumann, Andreas, Erbacher, Anna, Evangelisti, Camilla, Klapötke, Thomas M., Krumm, Burkhard, Rest, Sebastian F., Reynders, Martin, Sproll, Véronique

“…Various energetic polynitro esters, carbamates, and nitrocarbamates that were derived from the amino acid glycine were fully characterized by single‐crystal…”
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Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death by Borowiak, Malgorzata, Nahaboo, Wallis, Reynders, Martin, Nekolla, Katharina, Jalinot, Pierre, Hasserodt, Jens, Rehberg, Markus, Delattre, Marie, Zahler, Stefan, Vollmar, Angelika, Trauner, Dirk, Thorn-Seshold, Oliver

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Eine hochwertige photoschaltbare Sonde, die selektiv und wirksam den Transkriptionsfaktor RORγ moduliert by Reynders, Martin, Willems, Sabine, Marschner, Julian A., Wein, Thomas, Merk, Daniel, Thorn‐Seshold, Oliver

“…Der Retinsäure‐Rezeptor‐verwandte Waisen‐Rezeptor γ (RORγ) ist ein nuklearer Hormonrezeptor mit vielfältigen biologischen Funktionen in der Regulation der…”
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Failure to quantify viral load with two of the three commercial methods in a pregnant woman harboring an HIV type 1 subtype G strain by Debyser, Z, Van Wijngaerden, E, Van Laethem, K, Beuselinck, K, Reynders, M, De Clercq, E, Desmyter, J, Vandamme, A M

“…The level of HIV-1 RNA in plasma has become one of the most important markers in the follow-up of HIV-infected patients. Three techniques are commercially…”
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AIDS virus antibody in polytransfused dialysis patients vaccinated against hepatitis B by Desmyter, J, Reynders, M, Goubau, P

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