Search Results - "Reynaldo, Daniel P"
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A Dilated Cardiomyopathy Troponin C Mutation Lowers Contractile Force by Reducing Strong Myosin-Actin Binding
Published in The Journal of biological chemistry (04-06-2010)“…In this study we explore the mechanisms by which a double mutation (E59D/D75Y) in cardiac troponin C (CTnC) associated with dilated cardiomyopathy reduces the…”
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2
Heparin Binding by Murine Recombinant Prion Protein Leads to Transient Aggregation and Formation of RNA-Resistant Species
Published in Journal of the American Chemical Society (19-01-2011)“…The conversion of cellular prion protein (PrPC) into the pathological conformer PrPSc requires contact between both isoforms and probably also requires a…”
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Strong Cross-bridges Potentiate the Ca²⁺ Affinity Changes Produced by Hypertrophic Cardiomyopathy Cardiac Troponin C Mutants in Myofilaments: A FAST KINETIC APPROACH
Published in The Journal of biological chemistry (14-01-2011)“…This spectroscopic study examined the steady-state and kinetic parameters governing the cross-bridge effect on the increased Ca²⁺ affinity of hypertrophic…”
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4
Strong cross-bridges potentiate the Ca(2+) affinity changes produced by hypertrophic cardiomyopathy cardiac troponin C mutants in myofilaments: a fast kinetic approach
Published in The Journal of biological chemistry (14-01-2011)“…This spectroscopic study examined the steady-state and kinetic parameters governing the cross-bridge effect on the increased Ca(2+) affinity of hypertrophic…”
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Journal Article -
5
Strong Cross-bridges Potentiate the Ca2+ Affinity Changes Produced by Hypertrophic Cardiomyopathy Cardiac Troponin C Mutants in Myofilaments
Published in The Journal of biological chemistry (01-01-2011)“…This spectroscopic study examined the steady-state and kinetic parameters governing the cross-bridge effect on the increased Ca2+ affinity of hypertrophic…”
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Journal Article -
6
Strong Crossbridges are Required to Recapitulate the Ca2+ Affinity Changes Produced by HCM-cTnC Mutants in Skinned Fibers
Published in Biophysical journal (01-01-2010)Get full text
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