Search Results - "Reynaga, Rene"
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An improved protocol for generation and characterization of human-induced pluripotent stem cell-derived retinal pigment epithelium cells
Published in STAR protocols (16-12-2022)“…We present an optimized protocol for guided differentiation of retinal pigment epithelium (RPE) cells from human-induced pluripotent stem cells (iPSC). De…”
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Thiophene-based lipids for mRNA delivery to pulmonary and retinal tissues
Published in Proceedings of the National Academy of Sciences - PNAS (12-03-2024)“…Lipid nanoparticles (LNPs) largely rely on ionizable lipids to yield successful nucleic acid delivery via electrostatic disruption of the endosomal membrane…”
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Peptide-guided lipid nanoparticles deliver mRNA to the neural retina of rodents and nonhuman primates
Published in Science advances (13-01-2023)“…Lipid nanoparticle (LNP)-based mRNA delivery holds promise for the treatment of inherited retinal degenerations. Currently, LNP-mediated mRNA delivery is…”
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Preformed Vesicle Approach to LNP Manufacturing Enhances Retinal mRNA Delivery
Published in Small (Weinheim an der Bergstrasse, Germany) (01-09-2024)“…Complete encapsulation of nucleic acids by lipid‐based nanoparticles (LNPs) is often thought to be one of the main prerequisites for successful nucleic acid…”
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Development of a translatable gene augmentation therapy for CNGB1-retinitis pigmentosa
Published in Molecular therapy (05-07-2023)“…In this study, we investigate a gene augmentation therapy candidate for the treatment of retinitis pigmentosa (RP) due to cyclic nucleotide-gated channel beta…”
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Two-dimensional cellular automata of radius one for density classification task [formula omitted]
Published in Pattern recognition letters (01-11-2003)“…The study of a two-dimensional cellular automata (CA) able to perform density classification tasks for ρ= 1 2 is hereby presented. Results show that, for…”
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