Search Results - "Reyna, Dawn"

Longitudinal Monitoring of the Effects of Anti-Adenoviral Treatment Regimens in a Permissive In Vivo Model by Tollefson, Ann E, Cline-Smith, Anna, Spencer, Jacqueline F, Ying, Baoling, Reyna, Dawn M, Lipka, Elke, James, Scott H, Toth, Karoly

“…Adenovirus infections of immunocompromised patients can cause life-threatening disseminated disease. While there are presently no drugs specifically approved…”
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NPP-669, a Novel Broad-Spectrum Antiviral Therapeutic with Excellent Cellular Uptake, Antiviral Potency, Oral Bioavailability, Preclinical Efficacy, and a Promising Safety Margin by Lipka, Elke, Chadderdon, Aaron M., Harteg, Cheryl C., Doherty, Matthew K., Simon, Eric S., Domagala, John M., Reyna, Dawn M., Hutchings, Kim M., Gan, Xinmin, White, Andrew D., Hartline, Caroll B., Harden, Emma A., Keith, Kathy A., Prichard, Mark N., James, Scott H., Cardin, Rhonda D., Bernstein, David I., Spencer, Jacqueline F., Tollefson, Ann E., Wold, William S. M., Toth, Karoly

“…DNA viruses are responsible for many diseases in humans. Current treatments are often limited by toxicity, as in the case of cidofovir (CDV, Vistide), a…”
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A five-day treatment course of zanamivir for the flu with a single, self-administered, painless microneedle array patch: Revolutionizing delivery of poorly membrane-permeable therapeutics by Reyna, Dawn, Bejster, Ian, Chadderdon, Aaron, Harteg, Cheryl, Kurnia Anjani, Qonita, Hidayat Bin Sabri, Akmal, Brown, Ashley N., Drusano, George L., Westover, Jonna, Bart Tarbet, E., Vora, Lalitkumar K., Donnelly, Ryan F., Lipka, Elke

“…[Display omitted] Seasonal influenza virus infections cause a substantial number of deaths each year. While zanamivir (ZAN) is efficacious against…”
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Novel Formulation Strategy to Improve the Feasibility of Amifostine Administration by Ranganathan, Kavitha, Simon, Eric, Lynn, Jeremy, Snider, Alicia, Zhang, Yu, Nelson, Noah, Donneys, Alexis, Rodriguez, Jose, Buchman, Lauren, Reyna, Dawn, Lipka, Elke, Buchman, Steven R.

“…Purpose Amifostine (AMF), a radioprotectant, is FDA-approved for intravenous administration in cancer patients receiving radiation therapy (XRT)…”
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Evaluation of a method for measuring the radioprotective metabolite WR-1065 in plasma using chemical derivatization combined with UHPLC-MS/MS by Simon, Eric S., Reyna, Dawn, Lister, Richard J., Harteg, Cheryl, Lipka, Elke

“…Hypotension is the dose-limiting side effect of the radio-protective drug Amifostine and results from relaxation of the vascular smooth muscle, which is…”
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USC-087 protects Syrian hamsters against lethal challenge with human species C adenoviruses by Toth, Karoly, Spencer, Jacqueline F., Ying, Baoling, Tollefson, Ann E., Hartline, Caroll B., Richard, Eric T., Fan, Jiajun, Lyu, Jinglei, Kashemirov, Boris A., Harteg, Cheryl, Reyna, Dawn, Lipka, Elke, Prichard, Mark N., McKenna, Charles E., Wold, William S.M.

“…Human adenoviruses (AdV) cause generally mild infections of the respiratory and GI tracts as well as some other tissues. However, AdV can cause serious…”
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