Search Results - "Reymond, F."

In vitro iCLIP-based modeling uncovers how the splicing factor U2AF2 relies on regulation by cofactors by Sutandy, F X Reymond, Ebersberger, Stefanie, Huang, Lu, Busch, Anke, Bach, Maximilian, Kang, Hyun-Seo, Fallmann, Jörg, Maticzka, Daniel, Backofen, Rolf, Stadler, Peter F, Zarnack, Kathi, Sattler, Michael, Legewie, Stefan, König, Julian

“…Alternative splicing generates distinct mRNA isoforms and is crucial for proteome diversity in eukaryotes. The RNA-binding protein (RBP) U2AF2 is central to…”
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Decoding a cancer-relevant splicing decision in the RON proto-oncogene using high-throughput mutagenesis by Braun, Simon, Enculescu, Mihaela, Setty, Samarth T., Cortés-López, Mariela, de Almeida, Bernardo P., Sutandy, F. X.  Reymond, Schulz, Laura, Busch, Anke, Seiler, Markus, Ebersberger, Stefanie, Barbosa-Morais, Nuno L., Legewie, Stefan, König, Julian, Zarnack, Kathi

“…Mutations causing aberrant splicing are frequently implicated in human diseases including cancer. Here, we establish a high-throughput screen of randomly…”
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Ythdf is a N6‐methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila by Worpenberg, Lina, Paolantoni, Chiara, Longhi, Sara, Mulorz, Miriam M, Lence, Tina, Wessels, Hans‐Hermann, Dassi, Erik, Aiello, Giuseppe, Sutandy, F X Reymond, Scheibe, Marion, Edupuganti, Raghu R, Busch, Anke, Möckel, Martin M, Vermeulen, Michiel, Butter, Falk, König, Julian, Notarangelo, Michela, Ohler, Uwe, Dieterich, Christoph, Quattrone, Alessandro, Soldano, Alessia, Roignant, Jean‐Yves

“…N6‐methyladenosine (m 6 A) regulates a variety of physiological processes through modulation of RNA metabolism. This modification is particularly enriched in…”
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Magnetic nanocomposite fabrication using banana leaf sheath Biofluid: Enhanced Fenton catalytic activity towards tetracycline degradation by Edwin Vasu, A., Mary Sri Archana, A.P., Christopher Sagayaraj, A., Fabiyan Reymond, F., Antony Jasmine, V., Tony Elizabeth, A.

“…Impregnation of banana leaf sheath biomass along with its biofluid helps to produce a magnetite nanocomposite of better magnetic strength and tetracycline…”
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Battery longevity of neurostimulators in Parkinson disease: A historic cohort study by Sette, A.L., Seigneuret, E., Reymond, F., Chabardes, S., Castrioto, A., Boussat, B., Moro, E., François, P., Fraix, V.

“…Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a well-established treatment for motor complications in Parkinson disease (PD). Since 2012,…”
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Profiling the Binding Sites of RNA-Binding Proteins with Nucleotide Resolution Using iCLIP by Sutandy, F X Reymond, Hildebrandt, Andrea, König, Julian

“…The importance of posttranscriptional regulation in cellular metabolism has recently gone beyond what was previously appreciated. The regulatory mechanisms are…”
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The beginning of a new era: pioneering direct screens for RNA modulators by Sutandy, F. X. Reymond, Tharyan, Rebecca George, Münch, Christian

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A Human Proteome Microarray Identifies that the Heterogeneous Nuclear Ribonucleoprotein K (hnRNP K) Recognizes the 5′ Terminal Sequence of the Hepatitis C Virus RNA by Fan, Baochang, Lu, Kuan-Yi, Reymond Sutandy, F.X., Chen, Yi-Wen, Konan, Kouacou, Zhu, Heng, Kao, C. Cheng, Chen, Chien-Sheng

“…Stem-loop I (SL1) located in the 5′ untranslated region of the hepatitis C virus (HCV) genome initiates binding to miR-122, a microRNA required for hepatitis…”
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Systematic protein interactome analysis of glycosaminoglycans revealed YcbS as a novel bacterial virulence factor by Hsiao, Felix Shih-Hsiang, Sutandy, FX Reymond, Syu, Guan-Da, Chen, Yi-Wen, Lin, Jun-Mu, Chen, Chien-Sheng

“…Microbial pathogens have evolved several strategies for interacting with host cell components, such as glycosaminoglycans (GAGs). Some microbial proteins…”
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A cytosolic surveillance mechanism activates the mitochondrial UPR by Sutandy, F. X. Reymond, Gößner, Ines, Tascher, Georg, Münch, Christian

“…The mitochondrial unfolded protein response (UPR mt ) is essential to safeguard mitochondria from proteotoxic damage by activating a dedicated transcriptional…”
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Omics-based approaches for the systematic profiling of mitochondrial biology by Schäfer, Jasmin Adriana, Sutandy, F.X. Reymond, Münch, Christian

“…Mitochondria are essential for cellular functions such as metabolism and apoptosis. They dynamically adapt to the changing environmental demands by adjusting…”
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Improved library preparation with the new iCLIP2 protocol by Buchbender, Andreas, Mutter, Holger, Sutandy, F.X. Reymond, Körtel, Nadine, Hänel, Heike, Busch, Anke, Ebersberger, Stefanie, König, Julian

“…Individual-nucleotide resolution UV crosslinking and immunoprecipitation (iCLIP) is a state-of-the-art technology to map the RNA interaction sites of an…”
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An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2 by Kang, Hyun-Seo, Sánchez-Rico, Carolina, Ebersberger, Stefanie, Sutandy, F X Reymond, Busch, Anke, Welte, Thomas, Stehle, Ralf, Hipp, Clara, Schulz, Laura, Buchbender, Andreas, Zarnack, Kathi, König, Julian, Sattler, Michael

“…The recognition of -regulatory RNA motifs in human transcripts by RNA binding proteins (RBPs) is essential for gene regulation. The molecular features that…”
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Autoantibody profiling of monoamine oxidase A knockout mice, an autism spectrum disorder model by Syu, Guan-Da, Sutandy, F.X. Reymond, Chen, Kevin, Cheng, Yawei, Chen, Chien-Sheng, Shih, Jean C.

“…Monoamine oxidase A (MAO A) is the critical enzyme to degrade serotonin in the brain and the knockout mouse exhibits hyperserotonemia and abnormalities that…”
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FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns by Ebersberger, Stefanie, Hipp, Clara, Mulorz, Miriam M, Buchbender, Andreas, Hubrich, Dalmira, Kang, Hyun-Seo, Martínez-Lumbreras, Santiago, Kristofori, Panajot, Sutandy, F X Reymond, Llacsahuanga Allcca, Lidia, Schönfeld, Jonas, Bakisoglu, Cem, Busch, Anke, Hänel, Heike, Tretow, Kerstin, Welzel, Mareen, Di Liddo, Antonella, Möckel, Martin M, Zarnack, Kathi, Ebersberger, Ingo, Legewie, Stefan, Luck, Katja, Sattler, Michael, König, Julian

“…Splicing of pre-mRNAs critically contributes to gene regulation and proteome expansion in eukaryotes, but our understanding of the recognition and pairing of…”
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Generalization of Ionic Partition Diagrams to Lipophilic Compounds and to Biphasic Systems with Variable Phase Volume Ratios by Gobry, Véronique, Ulmeanu, Sorina, Reymond, Frédéric, Bouchard, Géraldine, Carrupt, Pierre-Alain, Testa, Bernard, Girault, Hubert H

“…The ionic partition diagram methodology has been generalized to address both hydrophilic and lipophilic compounds and to consider biphasic systems with…”
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Microchannel networks for electrophoretic separations by Rossier, Joël S., Schwarz, Alexandra, Reymond, Frédéric, Ferrigno, Rosaria, Bianchi, François, Girault, Hubert H.

“…UV excimer laser photoablation was used to micro‐machine polymer substrates not only to drill microchannel structures but also to change the surface physical…”
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Heterogeneous Ribonucleoprotein K (hnRNP K) Binds miR-122, a Mature Liver-Specific MicroRNA Required for Hepatitis C Virus Replication by Fan, Baochang, Sutandy, F.X. Reymond, Syu, Guan-Da, Middleton, Stefani, Yi, Guanghui, Lu, Kuan-Yi, Chen, Chien-Sheng, Kao, C.Cheng

“…Heterogeneous ribonucleoprotein K (hnRNP K) binds to the 5′ untranslated region of the hepatitis C virus (HCV) and is required for HCV RNA replication. The…”
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Asymmetric Synthesis and Antiviral Activities of l-Carbocyclic 2‘,3‘-Didehydro-2‘,3‘-dideoxy and 2‘,3‘-Dideoxy Nucleosides by Wang, Peiyuan, Gullen, Beth, Newton, M. Gary, Cheng, Yung-Chi, Schinazi, Reymond F, Chu, Chung K

“…Asymmetric syntheses of l-carbocyclic 2‘,3‘-didehydro-2‘,3‘-dideoxy- and 2‘,3‘-dideoxypyrimidine and purine nucleoside analogues were accomplished, and their…”
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High throughput platform to explore RNA-protein interactomes by Sutandy, F X Reymond, Hsiao, Felix Shih-Hsiang, Chen, Chien-Sheng

“…RNA binding proteins (RBPs) and RNA interaction is an emerging topic in molecular biology. Many reports showed that such interactions contribute to many…”
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