Search Results - "Reyes, Nabora S"

Intersection of Inflammation and Senescence in the Aging Lung Stem Cell Niche by Allen, Nancy C, Reyes, Nabora S, Lee, Jin Young, Peng, Tien

“…Aging is the final stage of development with stereotyped changes in tissue morphology. These age-related changes are risk factors for a multitude of chronic…”
Get full text

Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype by Wang, Chaoqun, de Mochel, Nabora S Reyes, Christenson, Stephanie A, Cassandras, Monica, Moon, Rebecca, Brumwell, Alexis N, Byrnes, Lauren E, Li, Alfred, Yokosaki, Yasuyuki, Shan, Peiying, Sneddon, Julie B, Jablons, David, Lee, Patty J, Matthay, Michael A, Chapman, Harold A, Peng, Tien

“…GWAS have repeatedly mapped susceptibility loci for emphysema to genes that modify hedgehog signaling, but the functional relevance of hedgehog signaling to…”
Get full text

Sentinel p16INK4a+ cells in the basement membrane form a reparative niche in the lung by Reyes, Nabora S, Krasilnikov, Maria, Allen, Nancy C, Jin Young Lee, Hyams, Ben, Zhou, Minqi, Ravishankar, Supriya, Cassandras, Monica, Wang, Chaoqun, Khan, Imran, Matatia, Peri, Johmura, Yoshikazu, Molofsky, Ari, Matthay, Michael, Nakanishi, Makoto, Sheppard, Dean, Campisi, Judith, Peng, Tien

“…Senescence marker revisitedSearching for cells that express the p16INK4a tumor suppressor, which is often used as a marker of senescence during aging, Reyes et…”
Get full text

An in vivo screening platform identifies senolytic compounds that target p16INK4a+ fibroblasts in lung fibrosis by Lee, Jin Young, Reyes, Nabora S, Ravishankar, Supriya, Zhou, Minqi, Krasilnikov, Maria, Ringler, Christian, Pohan, Grace, Wilson, Chris, Ang, Kenny Kean-Hooi, Wolters, Paul J, Tsukui, Tatsuya, Sheppard, Dean, Arkin, Michelle R, Peng, Tien

“…The appearance of senescent cells in age-related diseases has spurred the search for compounds that can target senescent cells in tissues, termed senolytics…”
Get full text

Sentinel p16 INK4a+ cells in the basement membrane form a reparative niche in the lung by Reyes, Nabora S, Krasilnikov, Maria, Allen, Nancy C, Lee, Jin Young, Hyams, Ben, Zhou, Minqi, Ravishankar, Supriya, Cassandras, Monica, Wang, Chaoqun, Khan, Imran, Matatia, Peri, Johmura, Yoshikazu, Molofsky, Ari, Matthay, Michael, Nakanishi, Makoto, Sheppard, Dean, Campisi, Judith, Peng, Tien

“…We engineered an ultrasensitive reporter of , a biomarker of cellular senescence. Our reporter detected -expressing fibroblasts with certain senescent…”
Get full text

In vivo protein turnover rates in varying oxygen tensions nominate MYBBP1A as a mediator of the hyperoxia response by Chen, Xuewen, Haribowo, Augustinus G, Baik, Alan H, Fossati, Andrea, Stevenson, Erica, Chen, Yiwen R, Reyes, Nabora S, Peng, Tien, Matthay, Michael A, Traglia, Michela, Pico, Alexander R, Jarosz, Daniel F, Buchwalter, Abigail, Ghaemmaghami, Sina, Swaney, Danielle L, Jain, Isha H

“…Oxygen deprivation and excess are both toxic. Thus, the body's ability to adapt to varying oxygen tensions is critical for survival. While the hypoxia…”
Get full text

An in vivo screening platform identifies senolytic compounds that target [p16.sup.INK4a+] fibroblasts in lung fibrosis by Lee, Jin Young, Reyes, Nabora S, Ravishankar, Supriya, Zhou, Minqi, Krasilnikov, Maria, Ringler, Christian, Pohan, Grace, Wilson, Chris, Ang, Kenny Kean-Hooi, Wolters, Paul J, Tsukui, Tatsuya, Sheppard, Dean, Arkin, Michelle R, Peng, Tien

“…The appearance of senescent cells in age-related diseases has spurred the search for compounds that can target senescent cells in tissues, termed senolytics…”
Get full text