Search Results - "Reyes, Edward"
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Integrated synthesis, modeling, and assessment (iSMA) of waste-to-resource alternatives towards a circular economy: The case of the chemical recycling of plastic waste management
Published in Computers & chemical engineering (01-07-2023)“…•Analyzing multiple waste-to-resource alternatives is key to attain circular economy.•The use of integrated process synthesis and knowledge management tools is…”
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Microglia play beneficial roles in multiple experimental seizure models
Published in Glia (01-07-2023)“…Seizure disorders are common, affecting both the young and the old. Currently available antiseizure drugs are ineffective in a third of patients and have been…”
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Mass Balance of Fipronil and Total Toxicity of Fipronil-Related Compounds in Process Streams during Conventional Wastewater and Wetland Treatment
Published in Environmental science & technology (02-02-2016)“…Attenuation of the pesticide fipronil and its major degradates was determined during conventional wastewater treatment and wetland treatment. Analysis of…”
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Characterization of kindled VGAT‐Cre mice as a new animal model of temporal lobe epilepsy
Published in Epilepsia (Copenhagen) (01-10-2020)“…Objective Development of novel therapies for temporal lobe epilepsy is hindered by a lack of models suitable for drug screening. While testing the hypothesis…”
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Mechanisms by which a CACNA1H mutation in epilepsy patients increases seizure susceptibility
Published in The Journal of physiology (15-02-2014)“…Key points Mutations in the Cav3.2 T‐type Ca2+ channel were found in patients with idiopathic generalized epilepsies, yet the mechanisms by which these…”
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Virus‐induced Hepatic Expression of an Oxidized Phospholipid‐binding Antibody Fragment Prevents Initiation of Hepatic Steatosis and Progression to Fibrosis
Published in The FASEB journal (01-05-2022)“…Oxidized phospholipids have been implicated in chronic pathologies. It had been shown that hyperlipidemic LDL‐R‐deficient mice transgenic for a single chain…”
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Protein Stabilization and Delivery: A Case Study of Invasion Plasmid Antigen D Adsorbed on Porous Silica
Published in Langmuir (01-12-2020)“…Approximately half of all vaccines produced annually are wasted because effectivity is dependent on protein structure and heat exposure disrupts the…”
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Comparison of white-to-white measurements using four devices and their determination of ICL sizing
Published in Eye and vision (Novato, Calif.) (02-10-2022)“…Background To compare the measurements obtained from the Orbscan II, IOLMaster 700, Pentacam AXL, and Castroviejo caliper and their effects on calculating the…”
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Enhanced actions of adenosine in medial entorhinal cortex layer II stellate neurons in temporal lobe epilepsy are mediated via A 1 ‐receptor activation
Published in Epilepsia (Copenhagen) (01-01-2012)“…Purpose: The adenosinergic system is known to exert an inhibitory affect in the brain, and as such adenosine has been considered an endogenous anticonvulsant…”
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Enhanced actions of adenosine in medial entorhinal cortex layer II stellate neurons in temporal lobe epilepsy are mediated via A1-receptor activation
Published in Epilepsia (Copenhagen) (01-01-2012)“…Summary Purpose: The adenosinergic system is known to exert an inhibitory affect in the brain, and as such adenosine has been considered an endogenous…”
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Assessing a Couples-Based, Digital HIV Serostatus-Neutral Intervention (Para Ti, Para Mí, Para Nosotros) for Adult Cisgender Sexual Minority Male Couples in Lima, Peru: Protocol for a 6-Month Pilot Randomized Controlled Trial
Published in JMIR research protocols (10-10-2024)“…HIV disproportionately affects sexual minority men (SMM; eg, gay, bisexual, and other men who have sex with men) in Lima, Peru; epidemiological data estimate…”
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Specific contribution of human T-type calcium channel isotypes (α1G, α1H and α1I) to neuronal excitability
Published in The Journal of physiology (01-04-2002)“…In several types of neurons, firing is an intrinsic property produced by specific classes of ion channels. Low-voltage-activated T-type calcium channels…”
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International Union of Pharmacology. XLVIII. Nomenclature and Structure-Function Relationships of Voltage-Gated Calcium Channels
Published in Pharmacological reviews (01-12-2005)“…The family of voltage-gated calcium channels serves as the key transducers of cell surface membrane potential changes into local intracellular calcium…”
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A novel therapeutic approach for treatment of catamenial epilepsy
Published in Neurobiology of disease (01-03-2018)“…Many women with epilepsy experience perimenstrual seizure exacerbation, referred to as catamenial epilepsy. There is no effective treatment for this condition,…”
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A potassium leak channel silences hyperactive neurons and ameliorates status epilepticus
Published in Epilepsia (Copenhagen) (01-02-2014)“…Summary Objective To develop a constitutively active K+ leak channel using TREK‐1 (TWIK‐related potassium channel 1; TREK‐M) that is resistant to compensatory…”
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Direct inhibition of T-type calcium channels by the endogenous cannabinoid anandamide
Published in The EMBO journal (17-12-2001)“…Low‐voltage‐activated or T‐type Ca2+ channels (T‐channels) are widely expressed, especially in the central nervous system where they contribute to pacemaker…”
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G protein-mediated inhibition of Cav3.2 T-type channels revisited
Published in Molecular pharmacology (01-02-2010)“…T-type calcium channels are important modulators of both membrane potential and intracellular Ca(2+) concentration, allowing them to play key roles in such…”
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EpiPro, a Novel, Synthetic, Activity-Regulated Promoter That Targets Hyperactive Neurons in Epilepsy for Gene Therapy Applications
Published in International journal of molecular sciences (23-09-2023)“…Epileptogenesis is characterized by intrinsic changes in neuronal firing, resulting in hyperactive neurons and the subsequent generation of seizure activity…”
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Central Mechanisms Mediating Thrombospondin-4-induced Pain States
Published in The Journal of biological chemistry (17-06-2016)“…Peripheral nerve injury induces increased expression of thrombospondin-4 (TSP4) in spinal cord and dorsal root ganglia that contributes to neuropathic pain…”
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LMO7 deficiency reveals the significance of the cuticular plate for hearing function
Published in Nature communications (08-03-2019)“…Sensory hair cells, the mechanoreceptors of the auditory and vestibular systems, harbor two specialized elaborations of the apical surface, the hair bundle and…”
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