Search Results - "Reyes, E"
-
1
A New Paradigm for Aptamer Therapeutic AS1411 Action: Uptake by Macropinocytosis and Its Stimulation by a Nucleolin-Dependent Mechanism
Published in Cancer research (Chicago, Ill.) (01-11-2010)“…AS1411 is a first-in-class anticancer agent, currently in phase II clinical trials. It is a quadruplex-forming oligodeoxynucleotide that binds to nucleolin as…”
Get full text
Journal Article -
2
Vivaria housing conditions expose sex differences in brain oxidation, microglial activation, and immune system states in aged hAPOE4 mice
Published in Experimental brain research (01-03-2024)“…Apolipoprotein E ε4 allele (APOE4) is the predominant genetic risk factor for late-onset Alzheimer’s disease (AD). APOE4 mouse models have provided advances in…”
Get full text
Journal Article -
3
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes
Published in Annual review of biochemistry (01-01-2009)“…Deubiquitinating enzymes (DUBs) are proteases that process ubiquitin or ubiquitin-like gene products, reverse the modification of proteins by a single…”
Get full text
Journal Article -
4
Mechanistic studies of anticancer aptamer AS1411 reveal a novel role for nucleolin in regulating Rac1 activation
Published in Molecular oncology (01-08-2015)“…AS1411 is a G-rich quadruplex-forming oligodeoxynucleotide that binds specifically to nucleolin, a protein found on the surface and in the cytoplasm of most…”
Get full text
Journal Article -
5
Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells
Published in Nature immunology (01-07-2018)“…Plasmacytoid dendritic cells (pDCs) are an immune subset devoted to the production of high amounts of type 1 interferons in response to viral infections…”
Get full text
Journal Article -
6
Helicobacter pylori and Its Role in Gastric Cancer
Published in Microorganisms (Basel) (17-05-2023)“…Gastric cancer is a challenging public health concern worldwide and remains a leading cause of cancer-related mortality. The primary risk factor implicated in…”
Get full text
Journal Article -
7
Involvement of Astrocytes in Alzheimer's Disease from a Neuroinflammatory and Oxidative Stress Perspective
Published in Frontiers in molecular neuroscience (19-12-2017)“…Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in humans, but still no curative treatment has been developed. Although many…”
Get full text
Journal Article -
8
Phytogenic Bioactive Compounds Shape Fish Mucosal Immunity
Published in Frontiers in immunology (18-06-2021)“…Aquaculture growth will unavoidably involve the implementation of innovative and sustainable production strategies, being functional feeds among the most…”
Get full text
Journal Article -
9
Plasmon induced enhanced photocatalytic activity of gold loaded hydroxyapatite nanoparticles for methylene blue degradation under visible light
Published in RSC advances (2017)“…A facile surfactant free wet-precipitation process was employed to prepare hydroxyapatite (HAp) nanoparticles. Further, a microwave-assisted hydrothermal…”
Get full text
Journal Article -
10
Klf4 Expression in Conventional Dendritic Cells Is Required for T Helper 2 Cell Responses
Published in Immunity (Cambridge, Mass.) (19-05-2015)“…The two major lineages of classical dendritic cells (cDCs) express and require either IRF8 or IRF4 transcription factors for their development and function…”
Get full text
Journal Article -
11
CaMKII as a Therapeutic Target in Cardiovascular Disease
Published in Annual review of pharmacology and toxicology (20-01-2023)“…CaMKII (the multifunctional Ca 2+ and calmodulin-dependent protein kinase II) is a highly validated signal for promoting a variety of common diseases,…”
Get full text
Journal Article -
12
Electric Field- and Strain-Induced Rashba Effect in Hybrid Halide Perovskites
Published in The journal of physical chemistry letters (15-09-2016)“…Using first-principles density functional theory calculations, we show how Rashba-type energy band splitting in the hybrid organic–inorganic halide perovskites…”
Get full text
Journal Article -
13
Alterations in Glucose Metabolism on Cognition: A Possible Link Between Diabetes and Dementia
Published in Current pharmaceutical design (01-02-2016)“…The use of the carbohydrate glucose as an energetic source is essential for an adequate function of the human body. The complex regulation of this molecule…”
Get more information
Journal Article -
14
Restoration conundrum: between nostalgia and futuralgia, moving beyond the reference state
Published in Restoration ecology (01-01-2024)“…Returning to the pristine reference state is a primary goal of ecosystem restoration. However, the concept has faced criticism due to its unrealistic nature…”
Get full text
Journal Article -
15
Transcriptional Control of Dendritic Cell Development
Published in Annual review of immunology (20-05-2016)“…The dendritic cells (DCs) of the immune system function in innate and adaptive responses by directing activity of various effector cells rather than serving as…”
Get full text
Journal Article -
16
Slow periodic activity in the longitudinal hippocampal slice can self‐propagate non‐synaptically by a mechanism consistent with ephaptic coupling
Published in The Journal of physiology (01-01-2019)“…Key points Slow periodic activity can propagate with speeds around 0.1 m s−1 and be modulated by weak electric fields. Slow periodic activity in the…”
Get full text
Journal Article -
17
Organs-on-a-Chip Module: A Review from the Development and Applications Perspective
Published in Micromachines (Basel) (22-10-2018)“…In recent years, ever-increasing scientific knowledge and modern high-tech advancements in micro- and nano-scales fabrication technologies have impacted…”
Get full text
Journal Article -
18
Astrocytes as a Therapeutic Target in Alzheimer’s Disease–Comprehensive Review and Recent Developments
Published in International journal of molecular sciences (01-11-2022)“…Alzheimer’s disease (AD) is a frequent and disabling neurodegenerative disorder, in which astrocytes participate in several pathophysiological processes…”
Get full text
Journal Article -
19
Mucosal Immunity and B Cells in Teleosts: Effect of Vaccination and Stress
Published in Frontiers in immunology (15-07-2015)“…Fish are subjected to several insults from the environment, which may endanger animal survival. Mucosal surfaces are the first line of defense against these…”
Get full text
Journal Article -
20
Fresh and mechanical behavior of a self-compacting concrete with additions of nano-silica, silica fume and ternary mixtures
Published in Construction & building materials (30-01-2018)“…•The use of nSi reduces the workability of SCC due to its high water demand.•The greater the quantity of nSi the greater is the demand of superplasticizer…”
Get full text
Journal Article