Search Results - "Rex, T. S."

A single intramuscular injection of rAAV‐mediated mutant erythropoietin protects against MPTP‐induced parkinsonism by Dhanushkodi, A., Akano, E. O., Roguski, E. E., Xue, Y., Rao, S. K., Matta, S. G., Rex, T. S., McDonald, M. P.

“…Erythropoietin (Epo) is neuroprotective in a number of preparations, but can lead to unacceptably high and even lethal hematocrit levels. Recent reports show…”
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Adenovirus-mediated delivery of catalase to retinal pigment epithelial cells protects neighboring photoreceptors from photo-oxidative stress by Rex, T S, Tsui, I, Hahn, P, Maguire, A M, Duan, D, Bennett, J, Dunaief, J L

“…Oxidative stress is involved in the pathogenesis of many diseases. Overexpression of antioxidant enzymes by gene therapy may protect tissues from oxidative…”
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Microsphere antioxidant and sustained erythropoietin-R76E release functions cooperate to reduce traumatic optic neuropathy by DeJulius, C.R., Bernardo-Colón, A., Naguib, S., Backstrom, J.R., Kavanaugh, T., Gupta, M.K., Duvall, C.L., Rex, T.S.

“…Wild-type erythropoietin (EPO) is promising for neuroprotection, but its therapeutic use is limited because it causes a systemic rise in hematocrit. We have…”
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Safety and angiogenic effects of systemic gene delivery of a modified erythropoietin by de Lucas Cerrillo, A M, Bond, W S, Rex, T S

“…Erythropoietin (EPO) is critical for red blood cell production and is also an effective neuroprotective agent. However, it may contribute to pathological…”
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The redox couple between glutathione and ascorbic acid: a chemical and physiological perspective by Winkler, B S, Orselli, S M, Rex, T S

“…This article provides a comprehensive analysis of the redox reaction between glutathione/glutathione disulfide and ascorbic acid/dehydroascorbic acid. It…”
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Distribution of S- and M-cones in normal and experimentally detached cat retina by Linberg, Kenneth A., Lewis, Geoffrey P., Shaaw, Chungling, Rex, Tonia S., Fisher, Steven K.

“…The lectin peanut agglutinin (PNA) and antibodies to short (S)‐ and medium to long wavelength (M/L)‐sensitive cones were utilized in order to define the…”
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Delayed vision loss and therapeutic intervention after blast injury by Rex, Tonia S

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Systemic adeno-associated virus-mediated gene therapy preserves retinal ganglion cells and visual function in DBA/2J glaucomatous mice by Sullivan, Timothy A, Geisert, Eldon E, Hines-Beard, Jessica, Rex, Tonia S

“…A slow progressive death of neurons is the hallmark of neurodegenerative diseases, such as glaucoma. A therapeutic candidate, erythropoietin (EPO), has shown…”
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In Utero Gene Therapy Rescues Vision in a Murine Model of Congenital Blindness by Dejneka, Nadine S, Surace, Enrico M, Aleman, Tomas S, Cideciyan, Artur V, Lyubarsky, Arkady, Savchenko, Andrey, Redmond, T.Michael, Tang, Waixing, Wei, Zhangyong, Rex, Tonia S, Glover, Ernest, Maguire, Albert M, Pugh, Edward N, Jacobson, Samuel G, Bennett, Jean

“…The congenital retinal blindness known as Leber congenital amaurosis (LCA) can be caused by mutations in the RPE65 gene. RPE65 plays a critical role in the…”
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Systemic but not intraocular Epo gene transfer protects the retina from light-and genetic-induced degeneration by Rex, Tonia S, Allocca, Mariacarmela, Domenici, Luciano, Surace, Enrico M, Maguire, Albert M, Lyubarsky, Arkady, Cellerino, Alessandro, Bennett, Jean, Auricchio, Alberto

“…Molecules with neurotrophic activity are being evaluated for treatment of retinitis pigmentosa in animal models. In particular, great interest has been focused…”
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Experimental retinal detachment: a paradigm for understanding the effects of induced photoreceptor degeneration by Fisher, S K, Stone, J, Rex, T S, Linberg, K A, Lewis, G P

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A Survey of Molecular Expression by Photoreceptors after Experimental Retinal Detachment by Rex, Tonia S, Fariss, Robert N, Lewis, Geoffrey P, Linberg, Kenneth A, Sokal, Iza, Fisher, Steven K

“…To describe changes in the localization patterns and levels of rod and cone photoreceptor proteins after experimental retinal detachment (RD). Cat retinas were…”
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Effect of over-expression of pigment epithelium derived factor (PEDF) on developing retinal vasculature in the mouse by Wong, Wai T, Rex, Tonia S, Auricchio, Alberto, Maguire, Albert M, Chung, Daniel, Tang, Waixing, Bennett, Jean

“…Pigment epithelium derived factor (PEDF) is a secreted protein with demonstrated anti-angiogenic properties, and with potential application for the treatment…”
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Differential expression of cone opsin mRNA levels following experimental retinal detachment and reattachment by Rex, Tonia S, Lewis, Geoffrey P, Geller, Scott F, Fisher, Steven K

“…To identify changes in S- and M-sensitive cone opsin gene expression following retinal detachment (RD) and reattachment. Cat retinas were detached for 1, 3, 7,…”
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DAVID MONRO'S LECTURE ON THE EXPRESSION OF PASSION, 1840 by CLAIR, REX E. WRIGHT-ST

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Analysis of SEER Adenosquamous Carcinoma Data to Identify Cause Specific Survival Predictors and Socioeconomic Disparities by Cheung, Rex

“…Background: This study used receiver operating characteristic curve to analyze Surveillance, Epidemiology and End Results (SEER) adenosquamous carcinoma data…”
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Analysis of SEER Glassy Cell Carcinoma Data: Underuse of Radiotherapy and Predicators of Cause Specific Survival by Cheung, Rex

“…Background: This study used receiver operating characteristic curve to analyze Surveillance, Epidemiology and End Results (SEER) for glassy cell carcinoma data…”
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Hope and healing without borders: an interview with Dr Shannon Melissa Chan by Liu, Alex Q, Hui, Rex WH

“…Dr Shannon Melissa Chan, an upper gastrointestinal surgeon and assistant professor from the Chinese University of Hong Kong, exemplifies what doctors can do to…”
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Making the world a better place: an interview with Dr Emily Chi-wan Hung by Hui, Rex WH, Liu, Alex Q

“…While studying for an undergraduate degree at the University of Cambridge in the United Kingdom, Dr Hung had completed a year of training in pathology and…”
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Racial and Socioeconomic Disparities in Malignant Carcinoid Cancer Cause Specific Survival: Analysis of the Surveillance, Epidemiology and End Results National Cancer Registry by Cheung, Rex

“…Background: This study hypothesized living in a poor neighborhood decreased the cause specific survival in individuals suffering from carcinoid carcinomas…”
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