Search Results - "Rewitz, K F"
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The Halloween genes code for cytochrome P450 enzymes mediating synthesis of the insect moulting hormone
Published in Biochemical Society transactions (01-12-2006)“…The developmental events occurring during moulting and metamorphosis of insects are controlled by precisely timed changes in levels of ecdysteroids, the…”
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Identification of two Nereis virens (Annelida: Polychaeta) cytochromes P450 and induction by xenobiotics
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01-05-2004)“…Cytochrome P450 (CYP) enzyme catalysed metabolism of xenobiotics such as polycyclic aromatic hydrocarbons (PAHs) are known to occur in polychaetes. Yet…”
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Identification, characterization and developmental expression of Halloween genes encoding P450 enzymes mediating ecdysone biosynthesis in the tobacco hornworm, Manduca sexta
Published in Insect biochemistry and molecular biology (01-03-2006)“…The insect molting hormone 20-hydroxyecdysone (20E) plays a central role in regulating gene expression during development and metamorphosis. In many…”
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Molecular evolution of the insect Halloween family of cytochrome P450s: Phylogeny, gene organization and functional conservation
Published in Insect biochemistry and molecular biology (01-08-2007)“…The insect molting hormone, 20-hydroxyecdysone (20E), is a major modulator of the developmental processes resulting in molting and metamorphosis. During…”
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A phosphoproteomics approach to elucidate neuropeptide signal transduction controlling insect metamorphosis
Published in Insect biochemistry and molecular biology (01-07-2009)“…In insects, the neuropeptide prothoracicotropic hormone (PTTH) stimulates production of ecdysone (E) in the prothoracic glands (PGs). E is the precursor of the…”
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Cytochrome P450 expression is moult stage specific and regulated by ecdysteroids and xenobiotics in the crab Carcinus maenas
Published in Biochemical and biophysical research communications (26-12-2008)“…The shore crab Carcinus maenas has a high capacity for metabolizing polycyclic aromatic hydrocarbons (PAHs). Cytochrome P450 (CYP) enzymes are involved in this…”
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Intermoult duration affects the susceptibility of shore crabs Carcinus maenas (L.) to pyrene and their ability to metabolise it
Published in Aquatic toxicology (01-12-2006)“…We have studied pyrene (PYR) toxicity and the ability to metabolise and eliminate PYR in two colour forms of shore crabs Carcinus maenas (Linnaeus, 1758). In…”
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Developmental expression of Manduca shade, the P450 mediating the final step in molting hormone synthesis
Published in Molecular and cellular endocrinology (09-03-2006)“…The ecdysone 20-monooxygenase (E20MO; 20-hydroxylase) is the enzyme that mediates the conversion of ecdysone (E) to the active insect molting hormone,…”
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