Search Results - "Revelli, David"

The impact of primary immunization route on the outcome of infection with SARS-CoV-2 in a hamster model of COVID-19 by Barrett, Edward G, Revelli, David, Bakshi, Chandra Shekhar, Kadish, Alan, Amar, Salomon

“…The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has resulted in over 6.7 million deaths worldwide. COVID-19 vaccines administered parenterally via…”
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Pharmacokinetic and Pharmacodynamic Effects of Polyclonal Antibodies against SARS-CoV2 in Mice by Jha, Aruni, Doyle-Eisele, Melanie, Revelli, David, Carnelley, Trevor, Barker, Douglas, Kodihalli, Shantha

“…Despite ongoing vaccination efforts to prevent SARS-CoV-2 infections, treatment tools are still necessary to address the ongoing COVID-19 pandemic. We report…”
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5-Azacytidine inhaled dry powder formulation profoundly improves pharmacokinetics and efficacy for lung cancer therapy through genome reprogramming by Kuehl, Philip J., Tellez, Carmen S., Grimes, Marcie J., March, Thomas H., Tessema, Mathewos, Revelli, David A., Mallis, Larry M., Dye, Wendy W., Sniegowski, Tyler, Badenoch, Aaron, Burke, Michael, Dubose, Devon, Vodak, David T., Picchi, Maria A., Belinsky, Steven A.

“…Background Epigenetic therapy through demethylation of 5-methylcytosine has been largely ineffective in treating lung cancer, most likely due to poor tissue…”
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Inhalation delivery dramatically improves the efficacy of topotecan for the treatment of local and distant lung cancer by Kuehl, Philip J., Yingling, Christin M., Dubose, Devon, Burke, Michael, Revelli, David A., Chen, Wenshu, Dye, Wendy W., Belinsky, Steven A., Tessema, Mathewos

“…Topotecan is potent anti-cancer drug approved for various malignancies but hematopoietic toxicities undermine its wider application and use of its most…”
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Inhalation delivery of topotecan is superior to intravenous exposure for suppressing lung cancer in a preclinical model by Kuehl, Philip J., Grimes, Marcie J., Dubose, Devon, Burke, Michael, Revelli, David A., Gigliotti, Andrew P., Belinsky, Steven A., Tessema, Mathewos

“…Intravenous (IV) topotecan is approved for the treatment of various malignancies including lung cancer but its clinical use is greatly undermined by severe…”
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A non-invasive intratracheal inoculation method for the study of pulmonary melioidosis by Revelli, David A, Boylan, Julie A, Gherardini, Frank C

“…Pulmonary melioidosis, a disease manifestation caused by the bacterium Burkholderia pseudomallei, has been studied using aerosols or intranasal (IN)…”
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Inhalable dry powders of a monoclonal antibody against SARS-CoV-2 virus made by thin-film freeze-drying by Xu, Haiyue, Sahakijpijarn, Sawittree, Moon, Chaeho, Emig, Christopher J., Mena, Marco, Henry, Steven J., Vitug, Adela, Ventura, Christian John, Kuehl, Philip J., Revelli, David, Owens, Donald E., Christensen, Dale J., Williams, Robert O., Cui, Zhengrong

“…[Display omitted] Monoclonal antibodies (mAbs) represent a promising modality for the prevention and treatment of viral infections. For infections that…”
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Local Treatment of Non-small Cell Lung Cancer with a Spray-Dried Bevacizumab Formulation by Shepard, Kimberly B., Vodak, David T., Kuehl, Philip J., Revelli, David, Zhou, Yue, Pluntze, Amanda M., Adam, Molly S., Oddo, Julia C., Switala, Lauren, Cape, Jonathan L., Baumann, John M., Banks, Michael

“…Local delivery of biotherapeutics to the lung holds great promise for treatment of lung diseases, but development of physically stable, biologically active dry…”
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Observed Reductions in the Infectivity of Bioaerosols Containing Bovine Coronavirus Under Repetitively Pulsed RF Exposure by Hoff, Brad W., Cohick, Zane W., Tilley, Burt S., Luginsland, John W., Revelli, David, Cox, Jason, Irshad, Hammad, Snider, Amanda, Arndt, Ariel, Ibey, Bennett L., Enderich, Daniel A., Thomas, Robert J., McConaha, Jeremy W., Franzi, Matthew A., Roach, William P., Shiffler, Donald A.

“…Objective: The purpose of the present study is to investigate the inactivation of bioaerosols containing Bovine Coronavirus, BCoV, under repetitively pulsed…”
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Apparatus for controlled microwave exposure of aerosolized pathogens by Hoff, Brad W, McConaha, Jeremy W, Cohick, Zane W, Franzi, Matthew A, Enderich, Daniel A, Revelli, David, Cox, Jason, Irshad, Hammad, Pohle, Hugh H, Schmitt-Sody, Andreas, Schaub, Samuel C, Baros, Anthony E, Lewis, Naomi C, Luginsland, John W, Lanagan, Michael T, Perini, Steven

“…A set of three apparatus enabling RF exposure of aerosolized pathogens at four chosen frequencies (2.8 GHz, 4.0 GHz, 5.6 GHz, and 7.5 GHz) has been designed,…”
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Nonlinear transmission line-driven apparatus for short-pulse microwave exposure of aerosolized pathogens by Enderich, Daniel A, Hoff, Brad W, Geiler, Michael, Geiler, Anton, Ottesen, Casey, Cohick, Zane W, McConaha, Jeremy W, Pohle, Hugh H, Franzi, Matthew A, Lepell, P David, Montoya, Thomas, Schrock, James A, Luginsland, John W, Revelli, David, Cox, Jason, Irshad, Hammad

“…A system capable of exposing a flowing aerosol stream to short duration (2-4 ns), high-power RF waveforms is described. The system utilizes a C-band…”
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The purification and characterization of the nonhemolytic phospholipase C of Pseudomonas aeruginosa by Revelli, David Aaron

“…Herein we report the purification and characterization of the nonhemolytic phospholipase C (PlcN) of the opportunistic pathogen, Pseudomonas aeruginosa. For…”
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A Noninvasive Intratracheal Inoculation Method for the Study of Pulmonary Melioidosis by David Aaron Revelli, Julie A Boylan, Frank C Gherardini

“…Pulmonary melioidosis, a disease manifestation caused by the bacterium Burkholderia pseudomallei, has been studied using aerosols or intranasal inoculation in…”
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