Search Results - "Revell, Victoria"
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Effect of sleep deprivation on the human metabolome
Published in Proceedings of the National Academy of Sciences - PNAS (22-07-2014)“…Sleep restriction and circadian clock disruption are associated with metabolic disorders such as obesity, insulin resistance, and diabetes. The metabolic…”
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2
Method to determine whether sleep phenotypes are driven by endogenous circadian rhythms or environmental light by combining longitudinal data and personalised mathematical models
Published in PLoS computational biology (22-12-2023)“…Sleep timing varies between individuals and can be altered in mental and physical health conditions. Sleep and circadian sleep phenotypes, including circadian…”
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3
S‐cone contribution to the acute melatonin suppression response in humans
Published in Journal of pineal research (01-08-2021)“…Light influences diverse aspects of human physiology and behaviour including neuroendocrine function, the circadian system and sleep. A role for…”
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4
Diurnal rhythms in the human urine metabolome during sleep and total sleep deprivation
Published in Scientific reports (09-10-2015)“…Understanding how metabolite levels change over the 24 hour day is of crucial importance for clinical and epidemiological studies. Additionally, the…”
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Sex differences in the circadian profiles of melatonin and cortisol in plasma and urine matrices under constant routine conditions
Published in Chronobiology international (02-01-2016)“…Conflicting evidence exists as to whether there are differences between males and females in circadian timing. The aim of the current study was to assess…”
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Effect of acute total sleep deprivation on plasma melatonin, cortisol and metabolite rhythms in females
Published in The European journal of neuroscience (01-01-2020)“…Disruption to sleep and circadian rhythms can impact on metabolism. The study aimed to investigate the effect of acute sleep deprivation on plasma melatonin,…”
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7
Machine learning estimation of human body time using metabolomic profiling
Published in Proceedings of the National Academy of Sciences - PNAS (02-05-2023)“…Circadian rhythms influence physiology, metabolism, and molecular processes in the human body. Estimation of individual body time (circadian phase) is…”
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8
Human Phase Response Curves to Three Days of Daily Melatonin: 0.5 mg Versus 3.0 mg
Published in The journal of clinical endocrinology and metabolism (01-07-2010)“…Context: Phase response curves (PRCs) to melatonin exist, but none compare different doses of melatonin using the same protocol. Objective: The aim was to…”
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Relationship between Human Pupillary Light Reflex and Circadian System Status
Published in PloS one (16-09-2016)“…Intrinsically photosensitive retinal ganglion cells (ipRGCs), whose photopigment melanopsin has a peak of sensitivity in the short wavelength range of the…”
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10
Machine‐learning‐derived sleep–wake staging from around‐the‐ear electroencephalogram outperforms manual scoring and actigraphy
Published in Journal of sleep research (01-04-2019)“…Quantification of sleep is important for the diagnosis of sleep disorders and sleep research. However, the only widely accepted method to obtain sleep staging…”
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Distinct Contributions of Rod, Cone, and Melanopsin Photoreceptors to Encoding Irradiance
Published in Neuron (Cambridge, Mass.) (13-05-2010)“…Photoreceptive, melanopsin-expressing retinal ganglion cells (mRGCs) encode ambient light (irradiance) for the circadian clock, the pupillomotor system, and…”
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12
A “Melanopic” Spectral Efficiency Function Predicts the Sensitivity of Melanopsin Photoreceptors to Polychromatic Lights
Published in Journal of biological rhythms (01-08-2011)“…Photoreception in the mammalian retina is not restricted to rods and cones but extends to a small number of intrinsically photosensitive retinal ganglion cells…”
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13
A three pulse phase response curve to three milligrams of melatonin in humans
Published in The Journal of physiology (15-01-2008)“…Exogenous melatonin is increasingly used for its phase shifting and soporific effects. We generated a three pulse phase response curve (PRC) to exogenous…”
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14
Human phase response curve to intermittent blue light using a commercially available device
Published in The Journal of physiology (01-10-2012)“…Key points • Misalignment between the internal circadian clock driving daily rhythms in physiology and behaviour, such as sleepiness, performance and…”
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15
Exposing 24-hour cycles in bile acids of male humans
Published in Nature communications (19-11-2024)“…Bile acids are trans-genomic molecules arising from the concerted metabolism of the human host and the intestinal microbiota and are important for digestion,…”
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Effects of the selective orexin-2 receptor antagonist JNJ-48816274 on sleep initiated in the circadian wake maintenance zone: a randomised trial
Published in Neuropsychopharmacology (New York, N.Y.) (01-02-2022)“…The effects of orexinergic peptides are diverse and are mediated by orexin-1 and orexin-2 receptors. Antagonists that target both receptors have been shown to…”
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17
The physiological period length of the human circadian clock in vivo is directly proportional to period in human fibroblasts
Published in PloS one (15-10-2010)“…Diurnal behavior in humans is governed by the period length of a circadian clock in the suprachiasmatic nuclei of the brain hypothalamus. Nevertheless, the…”
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18
Diurnal rhythms in blood cell populations and the effect of acute sleep deprivation in healthy young men
Published in Sleep (New York, N.Y.) (01-07-2012)“…The sleep/wake cycle is accompanied by changes in circulating numbers of immune cells. The goal of this study was to provide an in-depth characterization of…”
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Effect of sleep deprivation on rhythms of clock gene expression and melatonin in humans
Published in Chronobiology international (01-08-2013)“…This study investigated the impact of sleep deprivation on the human circadian system. Plasma melatonin and cortisol levels and leukocyte expression levels of…”
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20
Circadian regulation in human white adipose tissue revealed by transcriptome and metabolic network analysis
Published in Scientific reports (25-02-2019)“…Studying circadian rhythms in most human tissues is hampered by difficulty in collecting serial samples. Here we reveal circadian rhythms in the transcriptome…”
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