Search Results - "Reuter, Vincent"
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GEOfetch: a command-line tool for downloading data and standardized metadata from GEO and SRA
Published in Bioinformatics (Oxford, England) (01-03-2023)“…The Gene Expression Omnibus has become an important source of biological data for secondary analysis. However, there is no simple, programmatic way to download…”
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TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion
Published in The Journal of experimental medicine (07-02-2022)“…T cell receptor (TCR) signal strength is a key determinant of T cell responses. We developed a cancer mouse model in which tumor-specific CD8 T cells (TST…”
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2-hydroxyglutarate inhibits MyoD-mediated differentiation by preventing H3K9 demethylation
Published in Proceedings of the National Academy of Sciences - PNAS (25-06-2019)“…Oncogenic IDH1/2 mutations produce 2-hydroxyglutarate (2HG), resulting in competitive inhibition of DNA and protein demethylation. IDH-mutant cancer cells show…”
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L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer
Published in Nature cancer (01-01-2020)“…Metastasis-initiating cells with stem-like properties drive cancer lethality, yet their origins and relationship to primary-tumor-initiating stem cells are not…”
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PEPATAC: an optimized pipeline for ATAC-seq data analysis with serial alignments
Published in NAR genomics and bioinformatics (01-12-2021)“…Abstract As chromatin accessibility data from ATAC-seq experiments continues to expand, there is continuing need for standardized analysis pipelines. Here, we…”
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Refgenie: a reference genome resource manager
Published in Gigascience (01-02-2020)“…Abstract Background Reference genome assemblies are essential for high-throughput sequencing analysis projects. Typically, genome assemblies are stored on disk…”
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Linking big biomedical datasets to modular analysis with Portable Encapsulated Projects
Published in Gigascience (06-12-2021)“…Abstract Background Organizing and annotating biological sample data is critical in data-intensive bioinformatics. Unfortunately, metadata formats from a data…”
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Author Correction: L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer
Published in Nature cancer (01-11-2020)Get full text
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SWI/SNF Complex Mutations Promote Thyroid Tumor Progression and Insensitivity to Redifferentiation Therapies
Published in Cancer discovery (01-05-2021)“…Mutations of subunits of the SWI/SNF chromatin remodeling complexes occur commonly in cancers of different lineages, including advanced thyroid cancers. Here…”
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Abstract A12: L1CAM defines the regenerative origin of metastasis initiating cells in colorectal cancer
Published in Cancer research (Chicago, Ill.) (01-06-2020)“…Abstract Metastatic cancers relapse due to the emergence of stemlike clones capable of reversible quiescence, tumour reinitiation, and therapy resistance…”
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The chromatin accessibility landscape of primary human cancers
Published in Science (American Association for the Advancement of Science) (26-10-2018)“…We present the genome-wide chromatin accessibility profiles of 410 tumor samples spanning 23 cancer types from The Cancer Genome Atlas (TCGA). We identify…”
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Using Graphic Management Tools
Published in IEEE engineering management review (01-06-1981)“…This publication contains reprint articles for which IEEE does not hold copyright. Full text is not available on IEEE Xplore for these articles…”
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Staffing and Training for Work Study
Published in Personnel Journal (1971)“…Work Study may be defined as a combination of (1) methods study, which is a prerequisite to (2) work measurement. Most organizations include an industrial…”
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Work Study as a Tool for Increased Productivity and Profits
Published in Industrial management (Des Plaines) (01-03-1986)“…The field of work study is being used increasingly by companies to improve productivity. Work study is made up of 2 valuable techniques: 1. work design, which…”
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Wage Incentives: A Valued Management Tool
Published in Industrial management (Des Plaines) (01-07-1985)“…Currently, the continued viability of wage incentives as motivators is being questioned. While some suggest that wage incentives fail to motivate blue collar…”
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