Search Results - "Reuter, Kevin"

Mediating Passive Tumor Accumulation through Particle Size, Tumor Type, and Location by Perry, Jillian L, Reuter, Kevin G, Luft, J. Christopher, Pecot, Chad V, Zamboni, William, DeSimone, Joseph M

“…As the enhanced permeation and retention (EPR) effect continues to be a controversial topic in nanomedicine, we sought to examine EPR as a function of…”
Get full text

PEGylated PRINT Nanoparticles: The Impact of PEG Density on Protein Binding, Macrophage Association, Biodistribution, and Pharmacokinetics by Perry, Jillian L, Reuter, Kevin G, Kai, Marc P, Herlihy, Kevin P, Jones, Stephen W, Luft, J. Chris, Napier, Mary, Bear, James E, DeSimone, Joseph M

“…In this account, we varied PEGylation density on the surface of hydrogel PRINT nanoparticles and systematically observed the effects on protein adsorption,…”
Get full text

Physiologically Based Biopharmaceutics Modeling for Gefapixant IR Formulation Development and Defining the Bioequivalence Dissolution Safe Space by Wang, Michael, Heimbach, Tycho, Zhu, Wei, Wu, Di, Reuter, Kevin G., Kesisoglou, Filippos

“…Gefapixant is a weakly basic drug which has been formulated as an immediate release tablet for oral administration. A physiologically based biopharmaceutics…”
Get full text

Effect of basket mesh size on the hydrodynamics of a partially filled (500 mL) USP rotating basket dissolution testing Apparatus 1 by Sirasitthichoke, Chadakarn, Patel, Sanjaykumar, Reuter, Kevin G., Hermans, Andre, Bredael, Gerard, Armenante, Piero M.

“…[Display omitted] The USP Rotating Basket Dissolution Testing Apparatus 1 is listed in the USP as one of the tools to assess dissolution of oral solid dosage…”
Get full text

Influence of basket mesh size on the hydrodynamics in the USP rotating basket dissolution testing Apparatus 1 by Sirasitthichoke, Chadakarn, Patel, Sanjaykumar, Reuter, Kevin G., Hermans, Andre, Bredael, Gerard, Armenante, Piero M.

“…[Display omitted] •Velocity profiles with baskets of different mesh sizes were obtained using PIV.•Small deviations from perfect symmetry result in asymmetries…”
Get full text

Targeted PRINT Hydrogels: The Role of Nanoparticle Size and Ligand Density on Cell Association, Biodistribution, and Tumor Accumulation by Reuter, Kevin G, Perry, Jillian L, Kim, Dongwook, Luft, J. Christopher, Liu, Rihe, DeSimone, Joseph M

“…In this Letter, we varied targeting ligand density of an EGFR binding affibody on the surface of two different hydrogel PRINT nanoparticles (80 nm × 320 and 55…”
Get full text

Evaluation of drug loading, pharmacokinetic behavior, and toxicity of a cisplatin-containing hydrogel nanoparticle by Kai, Marc P., Keeler, Amanda W., Perry, Jillian L., Reuter, Kevin G., Luft, J. Christopher, O'Neal, Sara K., Zamboni, William C., DeSimone, Joseph M.

“…Cisplatin is a cytotoxic drug used as a first-line therapy for a wide variety of cancers. However, significant renal and neurological toxicities limit its…”
Get full text

USP Apparatus 4: a Valuable In Vitro Tool to Enable Formulation Development of Long-Acting Parenteral (LAP) Nanosuspension Formulations of Poorly Water-Soluble Compounds by Forrest, William P., Reuter, Kevin G., Shah, Vivek, Kazakevich, Irina, Heslinga, Michael, Dudhat, Siddhi, Patel, Sanjaykumar, Neri, Claudia, Mao, Yun

“…Long-acting or extended release parenteral dosage forms have attracted extensive attention due to their ability to maintain therapeutic drug concentrations…”
Get full text

Incidence, Risk Factors and Impact on Long-Term Outcome of Postoperative Delirium After Transcatheter Aortic Valve Replacement by Mauri, Victor, Reuter, Kevin, Körber, Maria I, Wienemann, Hendrik, Lee, Samuel, Eghbalzadeh, Kaveh, Kuhn, Elmar, Baldus, Stephan, Kelm, Malte, Nickenig, Georg, Veulemans, Verena, Jansen, Felix, Adam, Matti, Rudolph, Tanja K

“…The aim of the present study was to analyze incidence, risk factors, and association with long-term outcome of postoperative delirium (POD) after transcatheter…”
Get full text

Salient semantics by Reuter, Kevin

“…Semantic features are components of concepts. In philosophy, there is a predominant focus on those features that are necessary (and jointly sufficient) for the…”
Get full text

Analysis of human innate immune responses to PRINT fabricated nanoparticles with cross validation using a humanized mouse model by Robbins, Gregory R., BS, PhD, Roberts, Reid A., BS, PhD, Guo, Haitao, BS, PhD, Reuter, Kevin, BS, Shen, Tammy, BS, PhD, Sempowski, Gregory D., BS, PhD, McKinnon, Karen P., BS, PhD, Su, Lishan, BS, PhD, DeSimone, Joseph M., BS, PhD, Ting, Jenny P.-Y., BS, PhD

“…Abstract Ideal nanoparticle (NP)-based drug and vaccine delivery vectors should be free of inherent cytotoxic or immunostimulatory properties. Therefore,…”
Get full text

Calibration-quality cancer nanotherapeutics by Perry, Jillian L, Kai, Marc P, Reuter, Kevin G, Bowerman, Charles, Christopher Luft, J, DeSimone, Joseph M

“…Nanoparticle properties such as size, shape, deformability, and surface chemistry all play a role in nanomedicine drug delivery in cancer. While many studies…”
Get more information

Dual character concepts by Reuter, Kevin

“…Some of philosophy's most central concepts, including art, friendship, and happiness, have been argued to be dual character concepts. Their main characteristic…”
Get full text

Unfelt pain by Reuter, Kevin, Sytsma, Justin

“…The standard view in philosophy treats pains as phenomenally conscious mental states. This view has a number of corollaries, including that it is generally…”
Get full text

What is a Conspiracy Theory? by Napolitano, M. Giulia, Reuter, Kevin

“…In much of the current academic and public discussion, conspiracy theories are portrayed as a negative phenomenon, linked to misinformation, mistrust in…”
Get full text

Empirical Studies on Truth and the Project of Re‐engineering Truth by Reuter, Kevin, Brun, Georg

“…Most philosophers have largely downplayed any relevance of multiple meanings of the folk concept of truth in the empirical domain. However, confusions about…”
Get full text

What Is the Folk Concept of Life? by Beisbart, Claus, Reuter, Kevin

“…This paper details the content and structure of the folk concept of life, and discusses its relevance for scientific research on life. In four empirical…”
Get full text

Dual Character Concepts in Social Cognition: Commitments and the Normative Dimension of Conceptual Representation by Del Pinal, Guillermo, Reuter, Kevin

“…The concepts expressed by social role terms such as artist and scientist are unique in that they seem to allow two independent criteria for categorization, one…”
Get full text

Can commitments cause counterpreferential choices? by Messerli, Michael, Reuter, Kevin

“…Commitments are crucial for our lives but there is no consensus on how commitments and preferences relate to each other. In this paper, we present three…”
Get full text

The Developmental Challenge to the Paradox of Pain by Reuter, Kevin

“…People seem to perceive and locate pains in bodily locations, but also seem to conceive of pains as mental states that can be introspected. However, pains…”
Get full text