Search Results - "Reutens, Anne"

Epidemiology of Diabetic Kidney Disease by Reutens, Anne T., MBBS, PhD, FRACP

“…Diabetes currently affects 8.3% of the world's adults and will increase in prevalence in future decades. Diabetic kidney disease is a leading cause of end…”
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Acute metabolic and cardiovascular effects of mirabegron in healthy individuals by Loh, Rebecca K. C., Formosa, Melissa F., La Gerche, Andre, Reutens, Anne T., Kingwell, Bronwyn A., Carey, Andrew L.

“…Aims To quantify acute energy expenditure, supraclavicular skin temperature and cardiovascular responses to four doses of the β3‐adrenoceptor agonist,…”
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Sulodexide Fails to Demonstrate Renoprotection in Overt Type 2 Diabetic Nephropathy by PACKHAM, David K, WOLFE, Rory, CHAN, Juliana C. N, DE ZEEUW, Dick, LEWIS, Edmund J, ATKINS, Robert C, REUTENS, Anne T, BERL, Tomas, LAMBERS HEERSPINK, Hiddo, ROHDE, Richard, IVORY, Sara, LEWIS, Julia, RAZ, Itamar, WIEGMANN, Thomas B

“…Sulodexide, a mixture of naturally occurring glycosaminoglycan polysaccharide components, has been reported to reduce albuminuria in patients with diabetes,…”
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Sulodexide for Kidney Protection in Type 2 Diabetes Patients With Microalbuminuria: A Randomized Controlled Trial by Lewis, Edmund J., MD, Lewis, Julia B., MD, Greene, Tom, PhD, Hunsicker, Lawrence G., MD, Berl, Tomas, MD, Pohl, Marc A., MD, de Zeeuw, Dick, MD, PhD, Heerspink, Hiddo Lambers, PhD, Rohde, Richard D., BS, Atkins, Robert C., MD, Reutens, Anne T., MD, Packham, David K., MD, Raz, Itamar, MD

“…Background Sulodexide, a heterogenous group of sulfated glycosaminoglycans, includes low-molecular-weight heparin (∼80% ± 8%), high-molecular-weight heparin…”
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Pyridorin in Type 2 Diabetic Nephropathy by LEWIS, Edmund J, GREENE, Tom, YAGIL, Yoram, HERSKOVITS, Tommy, ATKINS, Robert C, REUTENS, Anne T, PACKHAM, David K, LEWIS, Julia B, SPITALEWIZ, Samuel, BLUMENTHAL, Samuel, BERL, Tomas, HUNSICKER, Lawrence G, POHL, Marc A, ROHDE, Richard D, RAZ, Itamar, YERUSHALMY, Yair

“…Pyridoxamine dihydrochloride (Pyridorin, NephroGenex) inhibits formation of advanced glycation end products and scavenges reactive oxygen species and toxic…”
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The association between cystatin C and incident type 2 diabetes is related to central adiposity by Reutens, Anne T, Bonnet, Fabrice, Lantieri, Olivier, Roussel, Ronan, Balkau, Beverley

“…Cystatin C has recently been shown to be associated with incident type 2 diabetes. This study aims to validate this association and to study the impact of…”
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Pioglitazone reduces cold-induced brown fat glucose uptake despite induction of browning in cultured human adipocytes: a randomised, controlled trial in humans by Loh, Rebecca K. C., Formosa, Melissa F., Eikelis, Nina, Bertovic, David A., Anderson, Mitchell J., Barwood, Shane A., Nanayakkara, Shane, Cohen, Neale D., La Gerche, Andre, Reutens, Anne T., Yap, Kenneth S., Barber, Thomas W., Lambert, Gavin W., Cherk, Martin H., Duffy, Stephen J., Kingwell, Bronwyn A., Carey, Andrew L.

“…Aims/hypothesis Increasing brown adipose tissue (BAT) activity is a possible therapeutic strategy to increase energy expenditure and glucose and lipid…”
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A physician-initiated double-blind, randomised, placebo-controlled, phase 2 study evaluating the efficacy and safety of inhibition of NADPH oxidase with the first-in-class Nox-1/4 inhibitor, GKT137831, in adults with type 1 diabetes and persistently elevated urinary albumin excretion: Protocol and statistical considerations by Reutens, Anne T., Jandeleit-Dahm, Karin, Thomas, Merlin, Salim, Agus, De Livera, Alysha M., Bach, Leon A., Colman, Peter G., Davis, Timothy M.E., Ekinci, Elif I., Fulcher, Greg, Hamblin, Peter Shane, Kotowicz, Mark A., MacIsaac, Richard J., Morbey, Claire, Simmons, David, Soldatos, Georgia, Wittert, Gary, Wu, Ted, Cooper, Mark E., Shaw, Jonathan E.

“…Kidney disease caused by type 1 diabetes can progress to end stage renal disease and can increase mortality risk. Nicotinamide adenine dinucleotide phosphate…”
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Evaluating the efficacy and safety of GKT137831 in adults with type 1 diabetes and persistently elevated urinary albumin excretion: a statistical analysis plan by De Livera, Alysha M, Reutens, Anne, Cooper, Mark, Thomas, Merlin, Jandeleit-Dahm, Karin, Shaw, Jonathan E, Salim, Agus

“…The investigational medicinal product GKT137831 is a selective inhibitor of NOX 1 and 4 isoforms of the nicotinamide adenine dinucleotide phosphate (NADPH)…”
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A pilot study to examine the tolerability and device preference in type 1 diabetes of insulin aspart administered by InsuJet compared with subcutaneous injection by Reutens, Anne T, Balkau, Beverley, Cohen, Neale

“…Jet injectors allow needle-free insulin delivery. The study objective was to compare the tolerability and device preference of subcutaneous insulin aspart…”
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Epidemiology of diabetic nephropathy by Reutens, Anne T, Atkins, Robert C

“…Diabetic nephropathy affects approximately one third of people with type 1 or type 2 diabetes mellitus. Risk factors affecting progression of kidney disease…”
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Diabetes Individualized therapy for diabetes mellitus-just a promise? by Reutens, Anne T

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Individualized therapy for diabetes mellitus—just a promise? by Reutens, Anne T.

“…To successfully tailor glycemic therapies to each patient with type 2 diabetes mellitus, the heterogeneity of the clinical features, pathogenesis and causative…”
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Correction to: Pioglitazone reduces cold-induced brown fat glucose uptake despite induction of browning in cultured human adipocytes: a randomised, controlled trial in humans by Loh, Rebecca K. C., Formosa, Melissa F., Eikelis, Nina, Bertovic, David A., Anderson, Mitchell J., Barwood, Shane A., Nanayakkara, Shane, Cohen, Neale D., La Gerche, Andre, Reutens, Anne T., Yap, Kenneth S., Barber, Thomas W., Lambert, Gavin W., Cherk, Martin H., Duffy, Stephen J., Kingwell, Bronwyn A., Carey, Andrew L.

“…The baseline insulin data given in Table 1 for the placebo group were incorrectly reported as 51 ± 10 pmol/l instead of 48 ± 10 pmol/l. This mistake also…”
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Cystatin C estimated glomerular filtration rate and all‐cause and cardiovascular disease mortality risk in the general population: AusDiab study by Barr, Elizabeth LM, Reutens, Anne, Magliano, Dianna J, Wolfe, Rory, Lu, Zhong X, Sikaris, Ken A, Tanamas, Stephanie K, Atkins, Robert, Chadban, Steve, Shaw, Jonathan E, Polkinghorne, Kevan R

“…Aims Uncertainties about the role of cystatin C‐based estimated glomerular filtration rate (eGFR) in the prediction of cardiovascular disease (CVD) beyond…”
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The GIANT study, a cluster-randomised controlled trial of efficacy of education of doctors about type 2 diabetes mellitus management guidelines in primary care practice by Reutens, Anne T, Hutchinson, Richard, Van Binh, Ta, Cockram, Clive, Deerochanawong, Chaicharn, Ho, Low-Tone, Ji, Linong, Khalid, Bin Abdul Kadir, Kong, Alice Pik Shan, Lim-Abrahan, Mary Ann, Tan, Chee-Eng, Tjokroprawiro, Askandar, Yoon, Kun-Ho, Zimmet, Paul Z, Shaw, Jonathan E

“…Abstract Objectives Primary aim: does general practitioner (GP) education on type 2 diabetes treatment improve HbA1c? Secondary aim: cardiovascular risk…”
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Residual proteinuria and eGFR predict progression of renal impairment within 2 years in type 2 diabetic patients with nephropathy who are receiving optimal treatment with angiotensin receptor blockers by Ivory, Sara E, Packham, David K, Reutens, Anne T, Wolfe, Rory, Rohde, Richard D, Lewis, Julia, Atkins, Robert C

“…Aim Proteinuria and estimated glomerular filtration rate (eGFR) predict progression of renal impairment in type 2 diabetic nephropathy (DN) but are they still…”
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Cyclin D1 Binds the Androgen Receptor and Regulates Hormone-Dependent Signaling in a p300/CBP-Associated Factor (P/CAF)-Dependent Manner by Reutens, Anne T, Fu, Maofu, Wang, Chenguang, Albanese, Chris, McPhaul, Michael J, Sun, Zijie, Balk, Steven P, Jänne, Olli A, Palvimo, Jorma J, Pestell, Richard G

“…The androgen receptor (AR) is a ligand-regulated member of the nuclear receptor superfamily. The cyclin D1 gene product, which encodes the regulatory subunit…”
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Type 2 diabetes strengthens the association between pulse pressure and chronic kidney disease: the AusDiab study by van den Hurk, Katja, Magliano, Dianna J, Alssema, Marjan, Schlaich, Markus P, Atkins, Robert C, Reutens, Anne T, Nijpels, Giel, Dekker, Jacqueline M, Shaw, Jonathan E

“…OBJECTIVEChronic kidney disease (CKD) is a serious disorder with significant public health impact. Identification of factors associated with risk of…”
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Endophilin-1: a multifunctional protein by Reutens, Anne T., Glenn Begley, C.

“…Endophilin-1, a cytoplasmic Src homology 3 (SH3) domain-containing protein, localises in brain presynaptic nerve termini. Endophilin dimerises through its…”
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